{ "cohort": { "cohort_id": "fnf-operative-rct-candidates-2010-2026", "default_candidate_scope": "Adult femoral-neck-fracture operative-strategy comparisons; the complete registry universe remains all ages.", "description": "A reproducible demonstration cohort of randomized interventional studies registered on ClinicalTrials.gov. The operative heuristic creates candidates for documented development curation; neither layer is a final systematic-review inclusion decision.", "interpretation_contract": [ "Registry eligibility text describes stated selection rules, not the enrolled population.", "Not mentioned is not equivalent to included.", "The operative lexicon is a transparent heuristic and requires independent human adjudication.", "The adult scope applies only to the default curated candidate view, not to the complete registry universe.", "Automated domain labels are evidence-navigation aids, not clinical or systematic-review judgments." ], "local_filters": { "allocation": "RANDOMIZED", "operative_candidate_screen": false, "requires_eligibility_text": true, "start_date_on_or_after": "2010-01-01", "study_type": "INTERVENTIONAL" }, "query": { "countTotal": "true", "fields": "NCTId,BriefTitle,OfficialTitle,StudyType,DesignAllocation,StartDate,CompletionDate,LastUpdatePostDate,OverallStatus,EnrollmentCount,EnrollmentType,InterventionType,InterventionName,InterventionDescription,ArmGroupLabel,ArmGroupDescription,EligibilityCriteria,MinimumAge,MaximumAge,Sex,StdAge,Condition,Keyword,LeadSponsorName,LocationCountry,HasResults", "filter.advanced": "AREA[StudyType]INTERVENTIONAL AND AREA[DesignAllocation]RANDOMIZED AND AREA[StartDate]RANGE[01/01/2010,MAX]", "format": "json", "markupFormat": "markdown", "pageSize": "1000", "query.cond": "\"femoral neck fracture\"" }, "source": { "endpoint": "https://clinicaltrials.gov/api/v2/studies", "name": "ClinicalTrials.gov API v2", "openapi_contract": "https://clinicaltrials.gov/api/oas/v2", "terms_url": "https://clinicaltrials.gov/about-site/terms-conditions", "version_endpoint": "https://clinicaltrials.gov/api/v2/version" }, "title": "Femoral-neck fracture operative-strategy trial candidates" }, "domains": [ { "counts": { "accommodating": 0, "mentioned": 1, "mixed": 0, "restrictive": 21, "silent": 20 }, "evidence_count": 25, "id": "cognition", "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "short_label": "Cognition" }, { "counts": { "accommodating": 9, "mentioned": 5, "mixed": 1, "restrictive": 11, "silent": 16 }, "evidence_count": 33, "id": "consent_support", "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "short_label": "Consent" }, { "counts": { "accommodating": 0, "mentioned": 0, "mixed": 0, "restrictive": 2, "silent": 40 }, "evidence_count": 2, "id": "residence", "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "short_label": "Residence" }, { "counts": { "accommodating": 0, "mentioned": 0, "mixed": 0, "restrictive": 19, "silent": 23 }, "evidence_count": 20, "id": "mobility", "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "short_label": "Mobility" }, { "counts": { "accommodating": 0, "mentioned": 0, "mixed": 0, "restrictive": 6, "silent": 36 }, "evidence_count": 6, "id": "language", "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "short_label": "Language" }, { "counts": { "accommodating": 0, "mentioned": 0, "mixed": 0, "restrictive": 14, "silent": 28 }, "evidence_count": 19, "id": "health_status", "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "short_label": "Health" }, { "counts": { "accommodating": 0, "mentioned": 0, "mixed": 0, "restrictive": 7, "silent": 35 }, "evidence_count": 8, "id": "life_expectancy", "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "short_label": "Prognosis" }, { "counts": { "accommodating": 0, "mentioned": 0, "mixed": 0, "restrictive": 15, "silent": 27 }, "evidence_count": 15, "id": "upper_age_cap", "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "short_label": "Age cap" } ], "pipeline": { "adjudication_status": "Single-pass development curation; independent human confirmation and trial-family adjudication are required before research use.", "candidate_scope": "Primary randomized operative-strategy candidates for adult femoral-neck fracture care", "cohort_manifest_sha256": "64e44bee992b08983bc28356e4b163e06ad3be71c18dfcc231741581037bd802", "curation_sha256": "d3515d10944bf5aa0ac7547999edf8031764ab4ff526e34fa1102dc8662ade8b", "curation_version": "0.1.0", "evidence_contract": "Every non-structured evidence quote must exactly equal its source-text slice.", "ontology_sha256": "19829cffe31c134ba62ea16178392b12855135f06c54c778e3bfadb5470d4368", "ontology_version": "0.1.0" }, "project": { "name": "TrialMirror", "repository": "https://github.com/AshishSara/trialmirror", "tagline": "Eligibility evidence, not a generalizability score." }, "retrieval": { "api_total_count": 121, "api_version": "2.0.5", "data_timestamp": "2026-08-13T09:00:04", "endpoint": "https://clinicaltrials.gov/api/v2/studies", "query": { "countTotal": "true", "fields": "NCTId,BriefTitle,OfficialTitle,StudyType,DesignAllocation,StartDate,CompletionDate,LastUpdatePostDate,OverallStatus,EnrollmentCount,EnrollmentType,InterventionType,InterventionName,InterventionDescription,ArmGroupLabel,ArmGroupDescription,EligibilityCriteria,MinimumAge,MaximumAge,Sex,StdAge,Condition,Keyword,LeadSponsorName,LocationCountry,HasResults", "filter.advanced": "AREA[StudyType]INTERVENTIONAL AND AREA[DesignAllocation]RANDOMIZED AND AREA[StartDate]RANGE[01/01/2010,MAX]", "format": "json", "markupFormat": "markdown", "pageSize": "1000", "query.cond": "\"femoral neck fracture\"" }, "records_received": 121, "request_urls": [ "https://clinicaltrials.gov/api/v2/studies?query.cond=%22femoral+neck+fracture%22&filter.advanced=AREA%5BStudyType%5DINTERVENTIONAL+AND+AREA%5BDesignAllocation%5DRANDOMIZED+AND+AREA%5BStartDate%5DRANGE%5B01%2F01%2F2010%2CMAX%5D&pageSize=1000&countTotal=true&format=json&markupFormat=markdown&fields=NCTId%2CBriefTitle%2COfficialTitle%2CStudyType%2CDesignAllocation%2CStartDate%2CCompletionDate%2CLastUpdatePostDate%2COverallStatus%2CEnrollmentCount%2CEnrollmentType%2CInterventionType%2CInterventionName%2CInterventionDescription%2CArmGroupLabel%2CArmGroupDescription%2CEligibilityCriteria%2CMinimumAge%2CMaximumAge%2CSex%2CStdAge%2CCondition%2CKeyword%2CLeadSponsorName%2CLocationCountry%2CHasResults" ], "retrieved_at": "2026-08-14T05:55:35Z", "snapshot_sha256": "2cb6d23e8777a60dd0937bab1959079318e9ed84392e23dc1c4b94aed924db49", "version_endpoint": "https://clinicaltrials.gov/api/v2/version" }, "schema_version": "0.1.0", "summary": { "countries": 43, "curation_delta": { "heuristic_demoted_to_linked_secondary": 1, "heuristic_excluded": 8, "heuristic_retained_as_primary": 36, "primary_added_by_override": 6 }, "evidence_items": 274, "funnel": { "date_eligible": 121, "has_eligibility_text": 121, "interventional": 121, "operative_candidates": 45, "randomized": 121, "received": 121 }, "heuristic_operative_candidates": 45, "linked_secondary_records": 3, "primary_candidates": 42, "records_with_posted_results": 7, "registry_universe": 121, "structured_evidence_items": 49, "text_evidence_spans": 225 }, "trials": [ { "allocation": "RANDOMIZED", "brief_title": "Prospective Randomized Comparison of Bipolar Hemiarthroplasty and Total Hip Arthroplasty With Large Femoral Heads for the Treatment of Displaced Intracapsular Femoral Neck Fractures in the Elderly", "completion_date": "2013-12", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Israel" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 279, "evidence_id": "041dc8371b3f1a19", "matched_rule": "\\babbreviated mental test\\b", "quote": "* 4\\. Abbreviated mental test score \\> 6 .", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 237 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 638, "evidence_id": "7cfd0a263da972d7", "matched_rule": "\\bsurgical risk\\b", "quote": "* 7\\. Very high surgical risk.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 608 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 539, "evidence_id": "d1aa1222d639d503", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* 4\\. Neurological disorder that may significantly influence walking ability and/or tendency to dislocate.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 433 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "672dc6bec21a1cf9", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* 1\\. Acute femoral neck fracture.\n* 2\\. Age between 70 and 90 years old.\n* 3\\. Independent community ambulator (more than 0.5km, without the aid of another person. The use of a cane is permitted) prior to fracture.\n* 4\\. Abbreviated mental test score \\> 6 .\n\nExclusion Criteria:\n\n* 1\\. Pathological fracture (excluding osteoporosis).\n* 2\\. Rheumatoid arthritis.\n* 3\\. Symptomatic arthrosis of the involved hip.\n* 4\\. Neurological disorder that may significantly influence walking ability and/or tendency to dislocate.\n* 5\\. Chronic corticosteroid use.\n* 6\\. Concomitant other fracture.\n* 7\\. Very high surgical risk.", "eligibility_sha256": "7db4ec12d043ea10bb8c882f2caf51df59f353d293f44085bcd31c0345a2756a", "enrollment": 80, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Total hip arthroplasty", "Hemiarthroplasty" ], "last_update_posted": "2011-06-17", "lead_sponsor": "Wolfson Medical Center", "masking": null, "maximum_age": "90 Years", "minimum_age": "70 Years", "nct_id": "NCT01109862", "official_title": "Prospective Randomized Comparison of Bipolar Hemiarthroplasty and Total Hip Arthroplasty With Large Femoral Heads for the Treatment of Displaced Intracapsular Femoral Neck Fractures in the Elderly", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "a85ebe3be9a5b6692600373f88b518c8587fae0531f55c32bd6cb0974585357a", "source_url": "https://clinicaltrials.gov/study/NCT01109862", "start_date": "2010-04", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Cemented Versus Uncemented Stems in Total Hip Arthroplasty in Patients With Femoral Neck Fractures", "completion_date": "2020-02-19", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Sweden" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "mentioned", "end": 441, "evidence_id": "9f9a3981ecc2fd04", "matched_rule": "\\bdementia\\b", "quote": "* Not dementia.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 426 }, { "effect": "restrictive", "end": 854, "evidence_id": "475855843f23b3f9", "matched_rule": "\\bdementia\\b", "quote": "* Dementia.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 843 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [ { "effect": "restrictive", "end": 425, "evidence_id": "17c91b8b41abbd8a", "matched_rule": "\\bindependent dwelling(?: conditions)?\\b", "quote": "* Coming from independent dwelling conditions.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 379 } ], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "restrictive" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "775c1872ff6a1485", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 85 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients who are acutely admitted to hospital with dislocated femoral neck fractures, that in clinical praxis are in the need of hip prosthesis surgery, are recruited in the study. The fracture shall not engage the lesser nor the greater trochanters.\n* Patients who wants to participate in the study and who can consider participation for at least 1 year.\n* Coming from independent dwelling conditions.\n* Not dementia.\n* Circa 60-85 years of age.\n* Circa 50 patients in each arm/group shall be included at M\u00f6lndal's Hospital (part of Sahlgrenska University Hospital).\n\nExclusion Criteria:\n\n* Patients who have difficulties in understanding the intent of the study.\n* Rheumatic disorders (RA, Bechterew, SLE).\n* Cortison treatment.\n* Stroke with remaining weakness or neurological disorders with affection of locomotion.\n* Dementia.\n* Grave obesity with BMI \\>=30-35.\n* Delay between time of injury and time of surgery exceeding 72 hours.", "eligibility_sha256": "176b16eff5035294b9bc1369c96e888b136c93d33d0a8ee9936f3cc7e53782fc", "enrollment": 109, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE", "PROCEDURE" ], "interventions": [ "Total Hip Arthroplasty", "Cemented Lubinus SPII stem (control arm)", "Uncemented HA Coated Corail stem" ], "last_update_posted": "2020-09-24", "lead_sponsor": "Sahlgrenska University Hospital", "masking": null, "maximum_age": "85 Years", "minimum_age": "60 Years", "nct_id": "NCT01578408", "official_title": "Corail-SP Study - A Prospective Randomized Comparison Between Cemented and Uncemented Hydroxyapatite Coated Prosthesis Stems in Total Hip Arthroplasty in Patients With Femoral Neck Fractures", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ae55585fdba8e6d2a40193dd64606bf52ba8efcfc37e78da019f779cf26bc555", "source_url": "https://clinicaltrials.gov/study/NCT01578408", "start_date": "2010-05-11", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Anterolateral Versus Posterior Approach for Total Hip Arthroplasty After Displaced Femoral Neck Fracture", "completion_date": "2013-11", "conditions": [ "Femur Fracture" ], "countries": [ "United States" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 152, "evidence_id": "9440ba7b24c68efe", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "Cognitive impairment", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 132 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 276, "evidence_id": "98db54a646dcb1b7", "matched_rule": "\\bcardiorespiratory disease\\b", "quote": "* Limited functional capacity (nursing home resident, non-ambulatory, severe cardiorespiratory disease)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 173 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 302, "evidence_id": "bdf38b30a7ba3f30", "matched_rule": "\\blife expectancy\\b", "quote": "* Limited life expectancy", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 277 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 276, "evidence_id": "19082bf3185ca347", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* Limited functional capacity (nursing home resident, non-ambulatory, severe cardiorespiratory disease)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 173 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [ { "effect": "restrictive", "end": 276, "evidence_id": "0bba6700bd2f5204", "matched_rule": "\\bnursing home\\b", "quote": "* Limited functional capacity (nursing home resident, non-ambulatory, severe cardiorespiratory disease)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 173 } ], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "restrictive" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Displaced femoral neck fracture\n* Age 65 years or older\n* Acute, femoral neck fracture\n\nExclusion Criteria:\n\nCognitive impairment\n\n* Active Infection\n* Limited functional capacity (nursing home resident, non-ambulatory, severe cardiorespiratory disease)\n* Limited life expectancy\n* Pathologic fracture (tumor)\n* Acetabular fractures", "eligibility_sha256": "63892c5eeaf40d71934d81635549533d02bbb1fa582ed527d06ed930e2dc8451", "enrollment": 16, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "posterior approach", "anterolateral approach" ], "last_update_posted": "2014-11-11", "lead_sponsor": "Florida Orthopaedic Institute", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT01484405", "official_title": "Anterolateral Versus Posterior Approach for Total Hip Arthroplasty After Displaced Femoral Neck Fracture", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "TERMINATED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "acef14614dd744ffc0da3268721ef101e73f3114830d8d0891c7d6fbe4836b5b", "source_url": "https://clinicaltrials.gov/study/NCT01484405", "start_date": "2010-06", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Minimal Invasive Anterior Approach Versus Trans-gluteal Approach for Hemi-arthroplasty in Femoral Neck Fractures", "completion_date": "2016-04", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "Switzerland" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 278, "evidence_id": "b1c7dc6e1e729f72", "matched_rule": "\\binformed consent\\b", "quote": "* Informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 260 }, { "effect": "restrictive", "end": 389, "evidence_id": "7092f98db25b2cdf", "matched_rule": "\\blegal representatives\\b", "quote": "* Refusal of consent by the patient or legal representatives to participate in the study", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 301 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 98, "evidence_id": "47efd108cedb3f07", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* Age of 60 years or more, ambulatory with/without walking aids before trauma", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age of 60 years or more, ambulatory with/without walking aids before trauma\n* Femoral neck fracture eligible for hemi-arthroplasty in accordance with the algorithm for femoral neck fracture patients used at the University hospital Basel\n* Informed consent\n\nExclusion Criteria:\n\n* Refusal of consent by the patient or legal representatives to participate in the study\n* More than one fracture\n* Suspicion of a pathological fracture in the context of known or unknown malignancy\n* Previous surgery of the proximal femur on the same side\n* Follow-up not possible (Tourist etc.)", "eligibility_sha256": "c854136adec0039933ded23146e45455ea1f2a49dd88773af427c7ad3e8d154e", "enrollment": 190, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Trans-gluteal approach, CLAS", "Anterior minimal invasive approach, AMIS" ], "last_update_posted": "2017-10-25", "lead_sponsor": "University Hospital, Basel, Switzerland", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT01408693", "official_title": "Minimal Invasive Anterior Approach Versus Trans-gluteal Approach for Hemi-arthroplasty in Femoral Neck Fractures - A Prospective Randomized Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "01f7000edede35d107f55c4386bc1ffdc7745da160747e8e8735200db712b3b3", "source_url": "https://clinicaltrials.gov/study/NCT01408693", "start_date": "2011-08", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Undisplaced Femoral Neck Fractures in the Elderly: A Trial Comparing Internal Fixation to Hemiarthroplasty", "completion_date": "2020-02-06", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Norway" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 620, "evidence_id": "8293b15fc7a2f4ab", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Temporarily impaired cognitive function:", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 578 }, { "effect": "restrictive", "end": 855, "evidence_id": "c8b4304aca84fb7d", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "(That is when the patient is judged as unable to provide an informed consent by the surgeon on call and there is no previous history of impaired cognitive function as documented by previous hospital record or a family member / proxy)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 622 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 855, "evidence_id": "1a0f42ef0fc692ba", "matched_rule": "\\binformed consent\\b", "quote": "(That is when the patient is judged as unable to provide an informed consent by the surgeon on call and there is no previous history of impaired cognitive function as documented by previous hospital record or a family member / proxy)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 622 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 513, "evidence_id": "56b1fc99f9fc9d47", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA IV patients as classified by the anesthesiologist on call", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 450 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 187, "evidence_id": "16c9b17306400157", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Patient able to walk before injury (all aids allowed)", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 132 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age 70 years or older\n* Undisplaced or minimally displaced intracapsular femoral neck fracture (Garden I/II)\n* Patient able to walk before injury (all aids allowed)\n* Patient lives within the catchment area of the three involved centres\n\nExclusion Criteria:\n\n* Displaced fractures (Garden III/IV) and impacted fractures with minimal varus\n* Pathologic fracture\n* Current soft tissue or deep infection in the hip or pelvis area\n* ASA IV patients as classified by the anesthesiologist on call\n* Other contraindications to either of the two methods compared\n* Temporarily impaired cognitive function:\n\n(That is when the patient is judged as unable to provide an informed consent by the surgeon on call and there is no previous history of impaired cognitive function as documented by previous hospital record or a family member / proxy)", "eligibility_sha256": "5f930b723689e637f558445e2ffe20d94d289acef0ce6962644c5529ca1a79cb", "enrollment": 220, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Hemi - arthroplasty", "internal fixation" ], "last_update_posted": "2017-11-06", "lead_sponsor": "University Hospital, Akershus", "masking": null, "maximum_age": null, "minimum_age": "70 Years", "nct_id": "NCT01770769", "official_title": "Undisplaced Femoral Neck Fractures in Patients Aged 70 Years and Older: A Multicentre Randomised Controlled Trial Comparing Internal Fixation to Hemiarthroplasty", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "719645faeabbcd12af2ceeed6c6931a74b370f2ff0997f699fcde71e2a9a7d69", "source_url": "https://clinicaltrials.gov/study/NCT01770769", "start_date": "2012-02-06", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Complications and Functional Outcome of Displaced Femoral Neck Fractures in Patients Younger Than 70 Years", "completion_date": "2020-12-31", "conditions": [ "Femoral Neck Fractures", "Osteoporosis" ], "countries": [ "Norway" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 335, "evidence_id": "9d3e2aadfaa75138", "matched_rule": "\\bdementia\\b", "quote": "* Senility or dementia or lack of competence to give informed consent to participate", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 251 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 335, "evidence_id": "67e5662f138b6325", "matched_rule": "\\binformed consent\\b", "quote": "* Senility or dementia or lack of competence to give informed consent to participate", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 251 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 483, "evidence_id": "86fc782a3e50adc4", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* Expected life duration less than 12 months and American Society of Anesthesiologists (ASA) 4 + 5", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 385 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 140, "evidence_id": "6d8949d037e423f4", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Able to walk before injury", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 112 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "e14075f711e4bc4b", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 70 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients with displaced femoral neck fractures Garden 3 or 4\n* Age between 55 - 70 years\n* Able to walk before injury\n\nExclusion Criteria:\n\n* Refusal to participate.\n* Pathological fractures for other reasons than osteoporosis.\n* Senility or dementia or lack of competence to give informed consent to participate\n* Fracture on the opposite side at the same time\n* Expected life duration less than 12 months and American Society of Anesthesiologists (ASA) 4 + 5\n* Amputated leg\n* Serious neurological disease that renders THA unsuitable\n* Substance narcotic abuse\n* Previous inclusion in the present study", "eligibility_sha256": "e9efc6054e3c36e8e016ef9c0ef21726efedbfd64978c479f50942dc7ed34e60", "enrollment": 118, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Total hip replacement arthroplasty", "Closed reduction and internal fixation" ], "last_update_posted": "2021-01-20", "lead_sponsor": "University Hospital, Akershus", "masking": null, "maximum_age": "70 Years", "minimum_age": "55 Years", "nct_id": "NCT02085707", "official_title": "Complications and Functional Outcome of Displaced Femoral Neck Fractures Treated With Internal Fixation vs Total Hip Arthroplasty in Patients Younger Than 70 Years. A Randomized Controlled Double Blind Multi Center Trial.", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "a0f2d1d81dfea8584966548faaef7416b9a034cc5c698ad97f48d3f4b1100034", "source_url": "https://clinicaltrials.gov/study/NCT02085707", "start_date": "2013-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Anterolateral Watson Jones Approach Versus Transgluteal Approach for Uncemented Hemi- Arthroplasty in Displaced Femoral Neck Fracture", "completion_date": "2022-03-11", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "Norway" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 126, "evidence_id": "e13479908f5d4654", "matched_rule": "\\bdementia\\b", "quote": "Dementia, Infection Not Suitable for Hemiarthroplasty", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 73 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "aca61842aa92495d", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria: Patients 70- 85 Years of Age -\n\nExclusion Criteria:\n\nDementia, Infection Not Suitable for Hemiarthroplasty\n\n\\-", "eligibility_sha256": "273dd4f506cbf07fddf1d64725dc32580dd686750c678dd23686448f687bc6eb", "enrollment": 150, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "hemiarthroplasty" ], "last_update_posted": "2022-11-10", "lead_sponsor": "Sorlandet Hospital HF", "masking": null, "maximum_age": "90 Years", "minimum_age": "70 Years", "nct_id": "NCT02028468", "official_title": null, "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "1f607a1399c219f89fb37f65ddfacc9509fa5cb43e83fc138005d46b9ed054f8", "source_url": "https://clinicaltrials.gov/study/NCT02028468", "start_date": "2014-02", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Dynaloc for Treatment of Femoral Neck Fractures", "completion_date": "2015-10", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "Denmark" ], "curation_reason": "Dynaloc versus cancellous-screw operative comparison missed by the initial lexicon.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 1612, "evidence_id": "24e7658f7ddf5632", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Moderate or severe cognitively impaired patients (i.e., Six Item Screener with three or more errors).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1509 }, { "effect": "restrictive", "end": 1791, "evidence_id": "438cbaefdc247b50", "matched_rule": "\\bdementia\\b", "quote": "* Patients with Parkinson's disease (or dementia or other neurological deficit) severe enough to increase the likelihood of falling or severe enough to compromise rehabilitation.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1613 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 890, "evidence_id": "9e0b740f3b4b55a2", "matched_rule": "\\binformed consent\\b", "quote": "* Provision of informed consent by patient or proxy.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 838 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 750, "evidence_id": "3d9b4d833bf043be", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* Patient was ambulatory prior to fracture, though they may have used an aid such as a cane or a walker.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 646 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "9d415ebc65af6693", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 110 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Adult men or women (see age specifications below) with subcapital femoral neck fractures (stable or unstable) confirmed with anteroposterior and lateral hip radiographs, computed tomography, or magnetic resonance imaging (MRI).\n* Patients between 50 and 69 years of age with any Garden type femoral neck fracture\n* Patients older than 70 years of age with femoral neck fractures Garden type I and II\n* Patients older than 70 years of age with a femoral neck fracture Garden types III and IV and contraindication to hemiarthroplasty.\n* Operative treatment within 4 days (i.e., 72 hours) of presenting to the emergency room.\n* Patient was ambulatory prior to fracture, though they may have used an aid such as a cane or a walker.\n* Anticipated medical optimalization of the patient for operative fixation of the hip.\n* Provision of informed consent by patient or proxy.\n* Low energy fracture (defined as a fall from standing height).\n* No other major trauma.\n\nExclusion Criteria:\n\n* Associated major injuries of the lower extremity (i.e., ipsilateral or contralateral fractures of the foot, ankle, tibia, fibula, knee, or femur; dislocations of the ankle, knee, or hip; or femoral head defects or fracture).\n* Retained hardware around the affected hip.\n* Abnormal opposite hip making end-point evaluation impossible\n* Infection around the hip (i.e., soft tissue or bone).\n* Patients with disorders of bone metabolism other than osteoporosis (i.e., Paget's disease, renal osteodystrophy).\n* Moderate or severe cognitively impaired patients (i.e., Six Item Screener with three or more errors).\n* Patients with Parkinson's disease (or dementia or other neurological deficit) severe enough to increase the likelihood of falling or severe enough to compromise rehabilitation.\n* Likely problems, in the judgment of the investigators, with maintaining follow-up. We will, for example, exclude patients with no fixed address, those who report a plan to move out of town in the next year, or intellectually challenged patients without adequate family support.", "eligibility_sha256": "03436aa1661b5704a06a7b0b64ee0a9bf376b233c048522fdc6f891803884e09", "enrollment": 150, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Dynaloc", "Cancellous screws" ], "last_update_posted": "2015-10-20", "lead_sponsor": "Aarhus University Hospital", "masking": null, "maximum_age": "110 Years", "minimum_age": "50 Years", "nct_id": "NCT02030431", "official_title": "Dynaloc vs. Multiple Cancellous Screws for Treatment of Femoral Neck Fractures", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "TERMINATED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "544b9e8f464393291fd6d8e96b1fb222f6296e6948bfc0d62596083920482303", "source_url": "https://clinicaltrials.gov/study/NCT02030431", "start_date": "2014-03", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Pinloc Versus Hansson Pins in the Treatment of Femoral Neck Fractures.", "completion_date": "2019-12", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Sweden" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Femoral neck fractures where the preferred treatment is internal fixation.\n\nExclusion Criteria:\n\n* Unwilling to participate.", "eligibility_sha256": "04befa5df04b0d53bff3b5b2dc55184935e2388cb8765568bf24b728b65dfd13", "enrollment": 537, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Pinloc", "Hansson Pins (LIH)" ], "last_update_posted": "2019-04-17", "lead_sponsor": "Torsten Johansson", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT02776631", "official_title": "Pinloc Versus Hansson Pins in the Treatment of Femoral Neck Fractures: A Prospective Randomized Study of 500 Patients", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "d70d8dd639ff4af47edf0b4e0439e120fe7b17a233962441a7a604adc45a1618", "source_url": "https://clinicaltrials.gov/study/NCT02776631", "start_date": "2014-05", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2)", "completion_date": "2019-03-18", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Australia", "Canada", "United States" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 295, "evidence_id": "8bcf1f6e64592813", "matched_rule": "\\binformed consent\\b", "quote": "5. Provision of informed consent by patient or substitute decision maker.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 222 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 1493, "evidence_id": "1b44e83efefed38e", "matched_rule": "\\bexpected to survive\\b", "quote": "14. Patient is not expected to survive injuries.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1445 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "09e15e9183253dc7", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 60 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria\n\n1. Adult men or women ages 18 to 60 years.\n2. Fracture of the femoral neck.\n3. Fracture amenable to both surgical treatments (SHS and cancellous screws).\n4. Operative treatment within 7 days of injury.\n5. Provision of informed consent by patient or substitute decision maker.\n\nExclusion Criteria\n\n1. Patients with previously diagnosed osteoporosis.\n2. Fracture-dislocation of the femoral neck and hip joint.\n3. Planned antegrade nailing of an ipsilateral femoral shaft fracture (if present).\n4. Current infection around the hip (i.e. soft tissue or bone).\n5. Stress fracture of the femoral neck.\n6. Pathologic fractures secondary to neoplasm or other bone lesion.\n7. Patients with known or likely undiagnosed disorders of bone metabolism such as Paget's disease, osteomalacia, osteopetrosis, osteogenesis imperfect, etc.\n8. Patients with hyperhomocysteinemia.\n9. Patient has an allergy to vitamin D or another contraindication to being prescribed vitamin D.\n10. Patient is currently taking an over counter drug and/or food supplement that contains vitamin D and is unable or unwilling to discontinue its use for this study.\n11. Likely problems, in the judgment of the attending surgeon, with maintaining follow up (e.g. patients with no fixed address, plans to move out of town). This may include patients with severe mental disorders and drug addictions without adequate support.\n12. Pregnancy.\n13. Patient is incarcerated.\n14. Patient is not expected to survive injuries.\n15. The attending surgeon believes the patient should be excluded because they are involved in a conflicting clinical trial.", "eligibility_sha256": "2397de4cfc7c7a0df97fa7c42401055f4830fa624474812bbd7739401c54bec6", "enrollment": 91, "enrollment_type": "ACTUAL", "has_results": true, "healthy_volunteers": null, "intervention_types": [ "DRUG", "PROCEDURE" ], "interventions": [ "Sliding Hip Screw", "Cancellous Screws", "Vitamin D", "Vitamin D Placebo" ], "last_update_posted": "2020-11-30", "lead_sponsor": "McMaster University", "masking": null, "maximum_age": "60 Years", "minimum_age": "18 Years", "nct_id": "NCT01908751", "official_title": "Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): A Multi-Centre 2x2 Factorial Randomized Trial Comparing Sliding Hip Screws Versus Cancellous Screws AND Vitamin D Versus Placebo on Patient Important Outcomes and Quality of Life in the Treatment of Young Adult (18-60) Femoral Neck Fractures", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "TERMINATED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "19b025c3ef5d2184022abae90dbcf1888ad449762bc98668582cf9cf52006112", "source_url": "https://clinicaltrials.gov/study/NCT01908751", "start_date": "2014-09", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Supercapsular Percutaneously Assisted Total Hip Approach for the Elderly With Femoral Neck Fractures", "completion_date": "2017-12", "conditions": [ "Femoral Neck Fractures" ], "countries": [], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 264, "evidence_id": "93d3a28c20070ee8", "matched_rule": "\\binformed consent\\b", "quote": "* Refusal to sign the informed consent.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 225 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Femoral head fractures as diagnosed by X-ran and CT;\n* Garden III, IV;\n* An age of \\> 75 years;\n* Both genders.\n\nExclusion Criteria:\n\n* Fractures with spinal cord injury;\n* Fractures with nerve injury;\n* Refusal to sign the informed consent.", "eligibility_sha256": "ee2efba04a981c472485f7dce0447c34af94b2dd8a373c21a900ea852eece5ba", "enrollment": 40, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Experimental group", "Control group" ], "last_update_posted": "2017-05-01", "lead_sponsor": "Shanghai Pudong Hospital", "masking": null, "maximum_age": null, "minimum_age": "75 Years", "nct_id": "NCT03134664", "official_title": "Supercapsular Percutaneously Assisted Total Hip Approach for the Elderly With Femoral Neck Fractures: a Prospective, Open-label, Randomized, Controlled Clinical Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "48337806f2b47b2ab120455d829fb3b15f52d643074490f6745f0280de7666c8", "source_url": "https://clinicaltrials.gov/study/NCT03134664", "start_date": "2015-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Project JAY HAP Registration Study", "completion_date": "2017-10-16", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "China" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 2058, "evidence_id": "12dc000af55205aa", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Subject has an emotional or neurological condition that would affect their ability or willingness to participate in the study (e.g. cognitive disorder, mental illness, mental retardation).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1868 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 510, "evidence_id": "fbca473ed2300318", "matched_rule": "\\binformed consent\\b", "quote": "* Subject who is able to give voluntary, written informed consent to participate in the study and from whom consent has been obtained by signing and dating an EC-approved consent form.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 326 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 770, "evidence_id": "fcbe0723233de933", "matched_rule": "\\blife expectancy\\b", "quote": "* Life expectancy of subject is over 2 years.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 725 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 325, "evidence_id": "4221262459abc096", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Subject is able to move independently before the fracture, with or without the use of walking aids .", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 223 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "7a62cd406bcfef4c", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Male or female subjects, aged between 65 and 90 years inclusive of Chinese ethnicity.\n* Subject presents with femoral neck fracture (Garden Type II, III, or IV) requiring hemiarthroplasty of the hip.\n* Subject is able to move independently before the fracture, with or without the use of walking aids .\n* Subject who is able to give voluntary, written informed consent to participate in the study and from whom consent has been obtained by signing and dating an EC-approved consent form.\n* Subject who is able to understand this clinical study, co-operates with the investigational procedures and is willing to return to the hospital for all the required post-operative follow-ups for up to 12 months.\n* Life expectancy of subject is over 2 years.\n\nExclusion Criteria:\n\n* Bilateral hip disease with the anticipated need for bilateral hip implant during study participation (i.e., within the next 12 months).\n* Subject experienced prior joint replacement surgery on any major joint (hip, knee) in lower limb within the last 12 months.\n* Subject has known or suspected metal sensitivity.\n* Subject is known to have insufficient bone stock resulting from conditions such as cancer, significant osteoporosis or metabolic bone disorders, which cannot provide adequate support and/or fixation to the prosthesis.\n* Subject is severely obese (BMI\\>35).\n* Subject is not suitable for hemiarthroplasty (i.e., inflammatory arthritis, pathological fractures, etc.)\n* Subject had an active infection or sepsis (treated or untreated)\n* Subject has conditions that may compromise implant stability or postoperative recovery (i.e., Paget's or Charcot's disease, vascular insufficiency, muscular atrophy, uncontrolled diabetes, moderate to severe renal insufficiency, hip abduction muscle strength less than grade IV or complete loss, or neuromuscular disease).\n* Subject has an emotional or neurological condition that would affect their ability or willingness to participate in the study (e.g. cognitive disorder, mental illness, mental retardation).\n* Subject is immunosuppressed, has an autoimmune disorder, or an immunosuppressive disorder. For examples, subject is on immunosuppressive therapy (corticosteroid hormones in large amounts, cytotoxic drugs, antilymphocytic serum or irradiation in large doses) or has acquired immunodeficiency syndrome (AIDS).\n* Subject is known to be at risk for lost to follow-up, or failure to return for scheduled visits.\n* Subject was enrolled in another investigational drug, biologic, or device study in the last 12 months.\n* Known alcohol and/or drug abuse", "eligibility_sha256": "4a79682134c753d5c7c57e1e672d77d73440d698849aec9a5da68d4f3b43793a", "enrollment": 134, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "SS Bipolar Head + SL-TWIN Stem", "Bipolar Head + SL-PLUS Stem" ], "last_update_posted": "2018-03-02", "lead_sponsor": "Smith & Nephew Orthopaedics (Beijing) Limited", "masking": null, "maximum_age": "90 Years", "minimum_age": "65 Years", "nct_id": "NCT02347397", "official_title": "A Prospective, Randomized, Multicenter Clinical Study in Elderly Chinese Subjects to Compare the Safety and Efficacy of the SS Bipolar Head and SL-TWIN Stem With Bipolar Head and SL-PLUS Stem in Hemiarthroplasty of the Hip", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "9479ce0e8ba78e3578f681260cc42b2b8a4fa403a769bd8b0f5e8be363661cfb", "source_url": "https://clinicaltrials.gov/study/NCT02347397", "start_date": "2015-04-29", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Feasibility of Implantation of Cemented Femoral Stem for Osteoporotic Femoral Neck Fracture in Elderly Patients", "completion_date": "2018-12", "conditions": [ "Femoral Neck Fracture" ], "countries": [], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 894, "evidence_id": "aeb2cbb19ac226b9", "matched_rule": "\\binformed consent\\b", "quote": "* Provision of informed consent about participation and trial procedure", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 823 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 1343, "evidence_id": "42e0c76ef0b9a963", "matched_rule": "\\b(?:able to |can |cannot )?tolerate (?:surgery|the operation)\\b", "quote": "* Inability to tolerate surgery", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1312 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "5af46d032a601fd7", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients with avascular necrosis of the femoral head diagnosed according to the previous criteria: Bone nonunion as indicated by a clear fracture line on X-ray images 12 months after femoral neck fracture; cystic degeneration, sclerosis, and uneven density on X-ray images and CT scans\n* Patients with osteoporosis diagnosed according to a previous report: Bone density T value \\< -2.5 or bone mass decrease by 25%\n* Patients with femoral neck fracture diagnosed according to the previous criteria (Chen and Wang, 2013): Presence of a fracture line on anterior- posterior X-ray images of the hip joint, and CT and MRI examination in combination with clinical symptoms and physical sign are necessary if no fracture line appears\n* Age 60-80 years\n* Healthy and able to tolerate anesthesia and surgery\n* Provision of informed consent about participation and trial procedure\n\nExclusion Criteria:\n\n* Alcohol abuse or long-term use of hormone drugs\n* Infection of tissue around the hip joint\n* Bone metabolism disorders other than osteoporosis, such as renal osteodystrophy and osteomalacia\n* Heart, lung, brain, or other systemic diseases\n* Advanced malignant tumor\n* Recent cerebral hemorrhage, myocardial infarction, or failure of important organs\n* Injured limb with deep venous thrombosis\n* Inability to tolerate surgery", "eligibility_sha256": "53cab5a656a769ea980f85bd0892b42092c483a024e7517eb348cf18ecb10b14", "enrollment": 100, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE", "PROCEDURE" ], "interventions": [ "cemented femoral stem", "cannulated compression screws" ], "last_update_posted": "2016-09-15", "lead_sponsor": "Qinghai University", "masking": null, "maximum_age": "80 Years", "minimum_age": "60 Years", "nct_id": "NCT02901938", "official_title": "Feasibility of Implantation of Cemented Femoral Stem in the Treatment of Osteoporotic Femoral Neck Fracture in Elderly Patients: a Randomized Controlled Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "a4985f561b08d303c003fa591c84b89789811ecc85c6b79360eab109a3301d06", "source_url": "https://clinicaltrials.gov/study/NCT02901938", "start_date": "2016-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Displaced Femoral Neck Fracture in Elderly Patient. Should Cement be Used for Hip Hemiarthroplasty ?", "completion_date": "2020-03-11", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "France" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 121, "evidence_id": "151ed982799d9601", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA score \\< or = III", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 98 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 184, "evidence_id": "5bc5e6fce94a87b4", "matched_rule": "\\bParker(?: mobility)? score\\b", "quote": "* Parker score \\<4", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 166 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* displaced femoral neck fractures (Garden III and IV)\n* 70 year old or more\n* ASA score \\< or = III\n* Lee score \\< or = 2\n\nExclusion Criteria:\n\n* Parker score \\<4\n* pathological femoral neck fracture ( paget disease or tumor)", "eligibility_sha256": "2d55307cfb89591fcf8a8e940e3e4318fa65ba054889262621f997a7ae62f4e7", "enrollment": 170, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "hemiarthroplasty for displaced femoral neck fractures" ], "last_update_posted": "2023-04-19", "lead_sponsor": "Centre Hospitalier Universitaire de Nice", "masking": null, "maximum_age": null, "minimum_age": "70 Years", "nct_id": "NCT01787929", "official_title": "Cemented Versus Uncemented Hemiarthroplasty for Displaced Femoral Neck Fracture in Elderly Patient : a Randomized Prospective Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "2594af2cfdb15c7bb3db930566cd97167ce11f7595bdd76990ab34b0c030b2f1", "source_url": "https://clinicaltrials.gov/study/NCT01787929", "start_date": "2016-02-07", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Undisplaced Femoral Neck Fractures 2 Hansson Pins or 3 Pins Interlocked in Plate (Pinloc) Using RSA", "completion_date": "2021-05", "conditions": [ "Hip Fractures", "Femoral Neck Fractures" ], "countries": [ "Norway" ], "curation_reason": "Pinloc versus Hansson-pins operative comparison missed by the initial lexicon.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 145, "evidence_id": "a839f4cde81a7154", "matched_rule": "\\bable to consent\\b", "quote": "* able to consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 128 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 195, "evidence_id": "0bb44da68644d0aa", "matched_rule": "\\bfit for surgery\\b", "quote": "* fit for surgery with pins with or without plate", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 146 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 407, "evidence_id": "e1cd72ffb4cce284", "matched_rule": "\\blife expectancy\\b", "quote": "* concomitant disease that will shorten life expectancy (i.e. cancer, COPD)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 332 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 127, "evidence_id": "e9d267aa84bc330f", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* able to walk independently, aids such as crutches or walker allowed", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 58 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* undisplaced femoral neck fractures\n* able to walk independently, aids such as crutches or walker allowed\n* able to consent\n* fit for surgery with pins with or without plate\n\nExclusion Criteria:\n\n* not willing or able to attain follow up\n* previous fracture or surgery with retained metal work in the same hip\n* concomitant disease that will shorten life expectancy (i.e. cancer, COPD)", "eligibility_sha256": "bba3e5bfd6afc77b89e19924e1380b50a7da917c08b581a8ccd429743b2547c6", "enrollment": 26, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Pinloc", "2 Hansson pins" ], "last_update_posted": "2021-05-11", "lead_sponsor": "Oslo University Hospital", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT02699619", "official_title": "Undisplaced Femoral Neck Fractures Treated With 2 Hansson Pins Without Plate or 3 Hansson Pins Interlocked in a Plate (Pinloc) - A Randomized Controlled Trial Using Radiostereometry", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ffd24c8c23af770e112a80375206c119b113d1f74bc2e718db0557462dcabaf1", "source_url": "https://clinicaltrials.gov/study/NCT02699619", "start_date": "2016-03", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Clinical and Functional Outcomes of Lateral vs Posterior Hemiarthroplasty", "completion_date": "2019-03-30", "conditions": [ "Femoral Neck Fractures", "Hip Fractures", "Hemiarthroplasty" ], "countries": [ "Turkey (T\u00fcrkiye)" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 203, "evidence_id": "d371b7f874f7e628", "matched_rule": "\\binformed consent\\b", "quote": "* Ability to provide informed consent by the patient or a legal representative", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 125 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age 60 years or older\n* Displaced intracapsular femoral neck fracture\n* Treated with hemiarthroplasty\n* Ability to provide informed consent by the patient or a legal representative\n\nExclusion Criteria:\n\n* Pathological femoral neck fractures\n* Previous surgery on the affected hip\n* Polytrauma patients\n* Periprosthetic fractures", "eligibility_sha256": "efb949fdff3651ab23248ef30da7769439a2c0a5c187ac9f7b42cf8016099d17", "enrollment": 225, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Posterior approach hemiarthroplasty", "Lateral approach hemiarthroplasty" ], "last_update_posted": "2026-01-15", "lead_sponsor": "Umraniye Education and Research Hospital", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT07345182", "official_title": "Lower Dislocation But Higher Fracture Risk: Posterior vs. Lateral Approaches in Hemiarthroplasty for Femoral Neck Fractures", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "67ba1b856016bf607d0314e8de1194dc5a3dd55efbafd07840447fb5db983fad", "source_url": "https://clinicaltrials.gov/study/NCT07345182", "start_date": "2016-03-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Direct Anterior vs. Anterolateral Approach for Hip Arthroplasty After Femoral Neck Fracture in the Senior Population", "completion_date": "2022-06-02", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "United States" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 154, "evidence_id": "62d62304a882f33c", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* preinjury ambulation with or without a gait aid", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 105 }, { "effect": "restrictive", "end": 311, "evidence_id": "395b179950c889d2", "matched_rule": "\\bwheelchair\\b", "quote": "* wheelchair bound", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 293 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* isolated displaced femoral neck fracture (AO type 31-B2 and 31 B3)\n* age\u226565 years\n* preinjury ambulation with or without a gait aid\n* surgical intervention \u2264 48 hours after fracture.\n\nExclusion Criteria:\n\n* age \\<65 years\n* patients with other fractures or dislocations\n* wheelchair bound\n* \\>48 hours between fracture and surgery, presence or history of infection, active metastatic disease, previous ipsilateral hip prosthesis\n* active major psychiatric illness\n* active drug or alcohol abuse\n* BMI \\>40, and actively failing contralateral hip prosthesis.", "eligibility_sha256": "96c5b5896e22d001563f9957efb5b0e18f1d453818b7ccbf8a57d8be96a85a28", "enrollment": 69, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Hip Hemiarthroplasty" ], "last_update_posted": "2023-01-06", "lead_sponsor": "Mayo Clinic", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT02959320", "official_title": "A Randomized Clinical Trial of Direct Anterior vs. Anterolateral Approach for Hip Arthroplasty After Femoral Neck Fracture in the Senior Population", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "940aaaa040064ac512218ecefd0f9eb349f6a9b955f3df6108e60e12e62f3c41", "source_url": "https://clinicaltrials.gov/study/NCT02959320", "start_date": "2016-11", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Fixation for the Treatment of Femoral Neck Fractures", "completion_date": "2018-12-30", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "China" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 253, "evidence_id": "0f321a513202b083", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* the absence of severe cognitive dysfunction,", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 207 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* closed femoral neck fracture\n* no fractures at other sites\n* surgical treatment with cannulated compression screws or PFNA\n* follow-up time greater than 1 years.\n\nExclusion Criteria:\n\n* the absence of severe cognitive dysfunction,\n* the presence of a pathological femoral neck fracture\n* previous femoral neck fracture, treated with other internal fixations and surgical treatment with open reduction.", "eligibility_sha256": "2351fe473921ac46a47b166061291c3aa1edcc2f580caab209fdd916df66e470", "enrollment": 150, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "fixation" ], "last_update_posted": "2018-06-13", "lead_sponsor": "Hebei Medical University Third Hospital", "masking": null, "maximum_age": null, "minimum_age": null, "nct_id": "NCT03550079", "official_title": "the Fixation Method for the Treatment of Femoral Neck Fractures", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4d41f8cafe91281d7df06a6ef509c8d8c232746017edbb47149d53f84f56952d", "source_url": "https://clinicaltrials.gov/study/NCT03550079", "start_date": "2017-10-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Surgical Approach of Hemiarthroplasty After Femoral Neck Fracture: Posterolateral or Direct Lateral", "completion_date": "2022-07-07", "conditions": [ "Hip Fractures", "Surgical Approach", "Hemiarthroplasty", "Posterolateral", "Direct Lateral" ], "countries": [ "Netherlands" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "mentioned", "end": 256, "evidence_id": "f0f189e5dbfee0f0", "matched_rule": "\\bmental impairment\\b", "quote": "* Informed consent or by proxy in patients with mental impairment", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 191 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "mentioned" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 256, "evidence_id": "86f0ca87c49dfa6e", "matched_rule": "\\binformed consent\\b", "quote": "* Informed consent or by proxy in patients with mental impairment", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 191 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [ { "effect": "restrictive", "end": 190, "evidence_id": "22f5dc099d5575f5", "matched_rule": "\\b(?:Danish|Dutch|English|French|German|Italian|Norwegian|Spanish|Swedish)(?:\\s+or\\s+[A-Za-z]+)?\\s+(?:fluency|literacy|language)\\b", "quote": "* Dutch or English fluency and literacy", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 151 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "restrictive" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* \u2265 18 years at time of trauma\n* Acute hip fracture\n* Hemiarthroplasty as recommended treatment according the national guidelines\n* Dutch or English fluency and literacy\n* Informed consent or by proxy in patients with mental impairment\n\nExclusion Criteria:\n\n* Multi-trauma-patient (ISS \\> 15)\n* Secondary surgery after failed internal fixation\n* Patients with a known metastatic disease and a confirmed pathological fracture of the hip\n* Fracture \\> 7 days at time of surgery\n* High risk of non-compliance/adherence to study procedures (e.g. no Dutch residency during follow-up period, or other factors that impair follow-up data collection)", "eligibility_sha256": "0be98ced4cc127a3737ff63adf18ff4517798a642498f5afe24afcde7db7fe6f", "enrollment": 555, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Surgical approach" ], "last_update_posted": "2022-12-21", "lead_sponsor": "JointResearch", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT04438226", "official_title": "Surgical Approach of Hemiarthroplasty After Femoral Neck Fracture: Posterolateral or Direct Lateral", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "39a4b996b98b2ae93cc47a864c45550bc57e8fa03bb87677cfa781023da31a61", "source_url": "https://clinicaltrials.gov/study/NCT04438226", "start_date": "2017-12-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Functional Outcome After Arthroplasty", "completion_date": "2020-09-30", "conditions": [ "Fracture Neck of Femur" ], "countries": [ "Egypt" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "7e3fd689285f1c27", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* active patients\n* displaced fracture neck of femur\n* age from 60 to 80\n\nExclusion Criteria:\n\n* ipsilateral previous hip surgery\n* grade 3 hip osteoarthritis according to tonnis classifiction\n* dysplastic acetabulum", "eligibility_sha256": "70e3b5b1f753fd6243ebb7cd29ce99dab0c48736c4941b7c7e4cfba24697ca9f", "enrollment": 33, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "arthroplasty" ], "last_update_posted": "2020-12-23", "lead_sponsor": "Ain Shams University", "masking": null, "maximum_age": "80 Years", "minimum_age": "60 Years", "nct_id": "NCT04680572", "official_title": "Functional Outcome After Dual Mobility Cups Total Hip Replacement Versus Bipolar Hemiarthroplasty in Fracture Neck of Femur in Active Elderly Patients", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "d6090d3569c48f1b9c840dc4fdd094b053a8dbdcce714eefd5a552d6a79497ac", "source_url": "https://clinicaltrials.gov/study/NCT04680572", "start_date": "2018-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Direct Anterior Approach for Femoral Neck Fractures", "completion_date": "2023-12-15", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Norway" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 752, "evidence_id": "fa5003913bc437d8", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* In case of severe cognitive impairment where the patients are not able to give their informed consent", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 649 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 752, "evidence_id": "481c413a22c60643", "matched_rule": "\\binformed consent\\b", "quote": "* In case of severe cognitive impairment where the patients are not able to give their informed consent", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 649 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 648, "evidence_id": "1a9f00e486870481", "matched_rule": "\\blife expectancy\\b", "quote": "* Patients with an underlying illness that doesn't have life expectancy beyond six months", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 559 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 558, "evidence_id": "a59472194ea24fa4", "matched_rule": "\\bnon[- ]?walkers?\\b", "quote": "* Bedridden patients/non-walkers", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 526 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Dislocated femoral neck fracture\n\nExclusion Criteria:\n\n* Infection around the hip (soft tissue or bone)\n* Pathologic fracture\n* Excessive alcohol or substance abuse that most likely will give reduced compliance\n* Patients with any fractures of the long bones in the lower extremity, fracture of the spine, and/or intra-thoracic or intra-abdominal injury (i.e., multiple trauma). Because the outcomes and clinical course of patients with multiple trauma may be quite different from a non-trauma patient.\n* Bedridden patients/non-walkers\n* Patients with an underlying illness that doesn't have life expectancy beyond six months\n* In case of severe cognitive impairment where the patients are not able to give their informed consent", "eligibility_sha256": "d26b328d86d4aea26b053923ba9ab0d7d83d7a53261a4fc23a485bc6e20005ae", "enrollment": 130, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Direct anterior approach", "Direct Lateral Approach" ], "last_update_posted": "2024-11-01", "lead_sponsor": "Helse M\u00f8re og Romsdal HF", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT03695497", "official_title": "A Randomized Controlled Trial Comparing Direct Anterior Approach to Direct Lateral Approach in Patients Receiving a Total Hip Arthroplasty for Femoral Neck Fracture - a 1 Year Follow-up Study", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "36e53f84e0bf120592d95c1d9e95d7dc8b0dd58820cec056da30fbb3bcf6560b", "source_url": "https://clinicaltrials.gov/study/NCT03695497", "start_date": "2018-10-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Hips Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients (HipSTHeR)", "completion_date": "2026-09-01", "conditions": [ "Femoral Neck Fractures", "Undisplaced Fracture" ], "countries": [ "Sweden" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 134, "evidence_id": "0b372f204cfdce0f", "matched_rule": "\\binformed consent\\b", "quote": "* informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 116 }, { "effect": "restrictive", "end": 216, "evidence_id": "b828a079cbf53c4f", "matched_rule": "\\binformed consent\\b", "quote": "* no informed consent", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 195 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Undisplaced (Garden I-II) femoral neck fracture (within 72h)\n* treated at participating unit\n* informed consent\n* amenable for both treatment options\n\nExclusion Criteria:\n\n* no informed consent\n* pathological or stress fracture\n* peri-implant fracture", "eligibility_sha256": "32096f4e6f551a1e62277ef2edab20da14efbca50aeeffe0a850cfbe3b032777", "enrollment": 1440, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Arthroplasty", "Internal Fixation" ], "last_update_posted": "2024-12-03", "lead_sponsor": "Uppsala University", "masking": null, "maximum_age": null, "minimum_age": "75 Years", "nct_id": "NCT03966716", "official_title": "HipSTHeR - a Registerbased Randomized Controlled Trial - Hip Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients.", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "de59ede30e3ff85c33b09c7d47e1579825486c43e90cb44be24fa32faa0dafaa", "source_url": "https://clinicaltrials.gov/study/NCT03966716", "start_date": "2019-09-16", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Dual Mobility Cups in Hip Fracture Patients", "completion_date": "2025-09-24", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Sweden", "United Kingdom" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 561, "evidence_id": "26bbe7484ee1c1b3", "matched_rule": "\\bdementia\\b", "quote": "* Dementia (as diagnosed by the screening physician)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 509 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 47, "evidence_id": "0e2d3e7d7502e02e", "matched_rule": "\\binformed consent\\b", "quote": "* Written informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Written informed consent\n* Diagnosis: displaced femoral neck fracture type AO 31-B2 or B3/Garden type 3 or 4\n* Eligible for THA according to local guidelines and routines\n\nExclusion Criteria:\n\n* Previous inclusion of contralateral hip\n* Delayed fracture surgery (date of injury \\>7 days prior to date of randomization)\n* Pathological or stress fracture of the femoral neck, or fracture adjacent to a previous ipsilateral hip implant\n* Inability or unwillingness to give written consent\n* Dementia (as diagnosed by the screening physician)\n* Unavailability of both interventions for a study subject (e.g., implants being out of stock, or lack of the individual surgeon's expertise to perform either procedure)", "eligibility_sha256": "885923cc08c1b0df45739f06822266369364b6227a3a3073bcabb70de295661f", "enrollment": 1600, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Dual mobility cup", "Standard cup" ], "last_update_posted": "2025-10-03", "lead_sponsor": "Uppsala University", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT03909815", "official_title": "Do Dual Mobility Cups Prevent Dislocation After Total Hip Arthroplasty Performed Due to Femoral Neck Fracture? A Registry-based, Pragmatic, Randomized Controlled Trial Comparing Dual Mobility With Standard Cups", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "860ecfe10106bdf4233b19c11a451608014590faf88e44bbaffca98ec620b953", "source_url": "https://clinicaltrials.gov/study/NCT03909815", "start_date": "2020-01-17", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Arthroplasty Versus Internal Fixation for Undisplaced Femoral Neck Fracture", "completion_date": "2025-01-26", "conditions": [ "Undisplaced Fracture", "Femoral Neck Fractures", "Internal Fixation; Complications", "Arthroplasty Complications" ], "countries": [ "Denmark" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 232, "evidence_id": "1f251534bc457fc3", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Cognitive intact in order to achieve informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 177 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 232, "evidence_id": "5c05c50a559ab941", "matched_rule": "\\binformed consent\\b", "quote": "* Cognitive intact in order to achieve informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 177 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [ { "effect": "restrictive", "end": 321, "evidence_id": "5c5a767c3a558df6", "matched_rule": "\\b(?:does not|unable to|cannot) speak\\b", "quote": "* The patient does not speak Danish", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 286 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "restrictive" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 176, "evidence_id": "e21bd2bc8a5c29d5", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* NMS (13) = 5 and above, indicating an ability to walk", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 121 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age \u2265 65 years old\n* Undisplaced femoral neck fracture\n* Posterior tilt (18) less than 20 degrees\n* NMS (13) = 5 and above, indicating an ability to walk\n* Cognitive intact in order to achieve informed consent\n\nExclusion Criteria:\n\n* The fracture is pathological\n* The patient does not speak Danish", "eligibility_sha256": "bf67075f9126b265cebb81a031db1c937e2f69a5d99a110d52e3789fac9e207b", "enrollment": 330, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Arthroplasty", "Internal fixation" ], "last_update_posted": "2025-03-25", "lead_sponsor": "University of Southern Denmark", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT04075461", "official_title": "Is arthroplaSty bEtter Than interNal Fixation in the undiSplaced Femoral nEck Fracture? A National Pragmatical Randomized Controlled Trial - the SENSE Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "102ece10a6744d7bc743673c931838ff0233d15b467fb598b1c58ffe3b6ab4ae", "source_url": "https://clinicaltrials.gov/study/NCT04075461", "start_date": "2020-02-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Direct Anterior Approach Versus Mini Posterior Approach Versous Lateral Approach for Displaced Femoral Neck Fractures", "completion_date": "2022-03-30", "conditions": [ "Hip Fractures", "Femoral Neck Fractures" ], "countries": [], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 640, "evidence_id": "1b33118ec7817e2d", "matched_rule": "\\bmentally incapable\\b", "quote": "* The exclusion criteria include open or pathological fractures, re-fractures, infection, concomitant injuries of the ipsi- or contralateral leg or upper limb, skin diseases in the area of proposed incisions, patients that are mentally incapable of understanding the consequences of the study and reduced compliance.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 324 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 301, "evidence_id": "62ef1c2822950dce", "matched_rule": "\\binformed consent\\b", "quote": "* Consecutive patients undergoing hip fracture surgery for displaced femoral neck fractures (Garden 3 and 4 fractures) and treated by cemented hemiarthroplasty will be included in the study. Patients must have the ability to give informed consent or a legal guardian is available.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Consecutive patients undergoing hip fracture surgery for displaced femoral neck fractures (Garden 3 and 4 fractures) and treated by cemented hemiarthroplasty will be included in the study. Patients must have the ability to give informed consent or a legal guardian is available.\n\nExclusion Criteria:\n\n* The exclusion criteria include open or pathological fractures, re-fractures, infection, concomitant injuries of the ipsi- or contralateral leg or upper limb, skin diseases in the area of proposed incisions, patients that are mentally incapable of understanding the consequences of the study and reduced compliance.", "eligibility_sha256": "2e584953109c7a9770092a248f3d74a17c34a9bbd901ff8baf16d3dde7c49fa0", "enrollment": 90, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Direct Anterior Approach Hemiarthroplasty", "Mini Posterior Approach", "Lateral approach" ], "last_update_posted": "2020-11-06", "lead_sponsor": "National and Kapodistrian University of Athens", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT04618549", "official_title": "Direct Anterior Approach (in Regular OR Table) Versus Mini Posterior Approach Versus Lateral Approach for the Treatment of Displaced Femoral Neck Fractures: A Prospective Randomized Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "c50621ece7f080c0cd400584769f2c2b22e7f8c3326c4d7df2bc13f305c9fb61", "source_url": "https://clinicaltrials.gov/study/NCT04618549", "start_date": "2020-11-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Does Capsulotomy in Closed Reduction of Femoral Neck Fractures Decrease Incidence of Avascular Necrosis?", "completion_date": "2023-02-01", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Egypt" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "539df62884badd1d", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 55 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Skeletally mature patients with fracture neck femur who will undergo urgent surgery within 48 hours.\n* Male and female patients of any garden classification of femoral neck fractures\n* within age group from 18 - 55 years\n\nExclusion Criteria:\n\n* Patients of age below 18 years or above 55 years.\n* those with metabolic bone disease, pathological fractures, stress fracture or delayed presentation more than 48 hours were excluded.", "eligibility_sha256": "8aec6cb9ca7e33376e7cb6be01018cb59e17c93d1a526e16671f1b0d703590e0", "enrollment": 40, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Capsulotomy and fixation", "Fixation only" ], "last_update_posted": "2024-05-31", "lead_sponsor": "Kasr El Aini Hospital", "masking": null, "maximum_age": "55 Years", "minimum_age": "18 Years", "nct_id": "NCT06436352", "official_title": "Does Capsulotomy in Closed Reduction of Femoral Neck Fractures Decrease Incidence of Avascular Necrosis?", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5fe777e019e18b24523bf736c9879f04b42705945330acc3b336077b5d838de3", "source_url": "https://clinicaltrials.gov/study/NCT06436352", "start_date": "2021-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Three Cancellous Screws Versus Four Cancellous Screws for Femoral Neck Fixation", "completion_date": "2026-12-31", "conditions": [ "Femoral Neck Fractures", "Internal Fixation" ], "countries": [ "China" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 504, "evidence_id": "ea353b9c7bc336d2", "matched_rule": "\\binformed consent\\b", "quote": "* Subjects (with the help of relatives) voluntarily provide written informed consent to participate in the clinical study and authorize the transfer of their information to the sponsor.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 319 }, { "effect": "restrictive", "end": 832, "evidence_id": "9cb972d09859fc01", "matched_rule": "\\bconsent to participate\\b", "quote": "* Subject does not provide voluntary consent to participate in the study.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 759 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 3192, "evidence_id": "fd254eb58fc3411f", "matched_rule": "\\bgait\\b", "quote": "* Subjects have significant neurological or musculoskeletal disorders or may have adverse effects on gait or weight-bearing (e.g., muscular dystrophy, multiple sclerosis, cerebral infarction, hemiplegia, Charcot arthropathy, avascular necrosis of the femoral head).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 2927 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age \u226518 years\n* Patients with unilateral femoral neck fractures that will be treated with internal fixation\n* According to AO fracture classification, subjects with the fracture type (31-B)\n* Subjects (with the help of relatives) can understand the informed documents and patient questionnaires.\n* Subjects (with the help of relatives) voluntarily provide written informed consent to participate in the clinical study and authorize the transfer of their information to the sponsor.\n* The investigator believes that the subject can understand the clinical study, is willing and able to complete all research procedures and follow-up visits and can cooperate with the research procedures.\n* In-label use of the MCS.\n\nExclusion Criteria:\n\n* Subject does not provide voluntary consent to participate in the study.\n* The researcher believes that the subjects have conditions that affect the participation and follow-up of this study. (for example, the patient lives in a remote area or has difficulty in going back to the hospital for follow-up or does not cooperate with the medical guidance and suggestions of the surgeon.)\n* The subjects were pregnant or lactating women.\n* The researchers believe that the subjects have psychological disorders, which may affect the treatment outcome.\n* Garden classification III and IV of femoral neck fracture patients older than 65 years\n* Concurrent hip osteoarthritis.\n* Fractures where the operative treatment will occur more than three weeks after the primary injury\n* Patients combined with femoral head fractures(31-C), femoral shaft fractures(32-A/B/C) or femoral trochanteric area fracture (31-A1/A2/A3).\n* Pathological fracture (e.g., primary or metastatic tumor)\n* Serious soft tissue injury, judged by the investigator, will impact the union of the fracture, combined vascular injury, and combined osteofascial compartment syndrome\n* Multiple systemic injuries judged by researchers not suitable for enrollment.\n* Revision surgeries (for example, due to malunion, nonunion or infection)\n* Concurrent medical conditions judged by researchers not suitable for enrollment, such as: metabolic bone disease, post-polio syndrome, poor bone quality, prior history of poor fracture healing, etc\n* Patients with anaesthetic and surgical contraindications\n* Patients known to be allergic to implant components\n* Patients who are currently using chemotherapeutics or accepting radiotherapy, use systematically corticosteroid hormone or growth factor, or long-term use sedative hypnotics (continuous use over 3 months) or non-steroidal anti-inflammatory drugs (continuous use over 3 months)\n* Intemperance judged by researchers not suitable for enrollment (e.g., excessive daily drinking or smoking, drug abuse);\n* Subjects participated in other clinical studies in the past 3 months, which may affect the outcome and follow-up according to the judgment of researchers.\n* Subjects have significant neurological or musculoskeletal disorders or may have adverse effects on gait or weight-bearing (e.g., muscular dystrophy, multiple sclerosis, cerebral infarction, hemiplegia, Charcot arthropathy, avascular necrosis of the femoral head).", "eligibility_sha256": "8aa3b5c62faf3e7cfc35a03ad9b591e57b60015e6645c5c8ecbcadfb19317ebe", "enrollment": 290, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "three cancellous screws", "four cancellous screws" ], "last_update_posted": "2021-05-03", "lead_sponsor": "Peking University Third Hospital", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT04869332", "official_title": "A Prospective Randomised Controlled Clinical Trial: Three Cancellous Screws Versus Four Cancellous Screws for Fixation of Femoral Neck Fractures", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "d0e9205878b57c35a771aa19fb030c81bc542032565d410b8eb9521527a15feb", "source_url": "https://clinicaltrials.gov/study/NCT04869332", "start_date": "2021-04-08", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Surgical Approach in Hemiarthroplasty. A Randomized Clinical Trial Comparing Posterior and Anterior Approach", "completion_date": "2026-09-10", "conditions": [ "Femoral Neck Fractures", "Bone Mineral Density", "Muscle Damage", "Surgical Approach" ], "countries": [ "Norway" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 389, "evidence_id": "d2d3d70a5be19f7f", "matched_rule": "\\bdementia\\b", "quote": "* Dementia", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 379 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 283, "evidence_id": "3ec46e40d56649f4", "matched_rule": "\\binformed consent\\b", "quote": "* Provision of informed consent by patient or proxy", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 232 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 143, "evidence_id": "26d19f5b642a7a67", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Ability to walk with or without a walking aid prior to falling", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 79 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "bb257b991a223774", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients between 70 and 90 years of age\n* Displaced FNF\n* Ability to walk with or without a walking aid prior to falling\n* Patients having Sorlandet Hospital as primary service provider for orthopaedic trauma\n* Provision of informed consent by patient or proxy\n* Low energy fracture (fall from standing height, no other major trauma)\n\nExclusion Criteria:\n\n* Dementia\n* Fractures in pathologic bone\n* Patients not suited for HA (i.e., inflammatory arthritis, severe osteoarthritis)\n* Associated major injuries of the lower extremity ( i.e., ipsilateral or contralateral fractures of the foot, ankle, tibia, fibula or femur)\n* Retained hardware around the affected hip that will interfere with arthroplasty\n* Sepsis or local infection", "eligibility_sha256": "4792c416bb39d4ddfd7e8eaea65b88b2a85d55f749e2760c349548fd16c1aee5", "enrollment": 210, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Posterior SPAIRE approach, anterior approach" ], "last_update_posted": "2026-05-08", "lead_sponsor": "Sorlandet Hospital HF", "masking": null, "maximum_age": "90 Years", "minimum_age": "70 Years", "nct_id": "NCT04900506", "official_title": "Cemented Hemiarthroplasty in Femoral Neck Fractures; Are Clinical Results Affected by Surgical Approach. A Randomized Clinical Trial Comparing Posterior and Anterior Approach", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "63332673482029f7285e2b3f13ecf39bff402dc53a059d18acd276b159a8eae5", "source_url": "https://clinicaltrials.gov/study/NCT04900506", "start_date": "2022-01-21", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparison of Direct Anterior Approach vs. Lateral Hemiarthroplasty for Femoral Neck Fracture Repair", "completion_date": "2025-02", "conditions": [ "Hip Fractures" ], "countries": [ "Canada" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 169, "evidence_id": "f1af29281936dcd5", "matched_rule": "\\binformed consent\\b", "quote": "* Patients capable of reading, writing and signing an informed consent form", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 94 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [ { "effect": "restrictive", "end": 169, "evidence_id": "9ce4798719db2560", "matched_rule": "\\bcapable of reading,? writing(?: and signing)?\\b", "quote": "* Patients capable of reading, writing and signing an informed consent form", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 94 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "restrictive" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Any patient undergoing a hemiarthroplasty for a femoral neck fracture;\n* Patients capable of reading, writing and signing an informed consent form\n\nExclusion Criteria:\n\n* Patients under the age of 18", "eligibility_sha256": "c8b87140e58ccbc0be40c109aabd8d09c4d0eb43f76fd45b0183683a0ae2c402", "enrollment": 120, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "surgical approach" ], "last_update_posted": "2023-11-13", "lead_sponsor": "Ottawa Hospital Research Institute", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT05173155", "official_title": "Comparison of Direct Anterior Approach vs. Lateral Hemiarthroplasty for Femoral Neck Fracture Repair: A Short-term Outcomes Study", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "096540917ea6259da62d852f5f96415d6f1b7495c3a37ba0800e2a8624d68be6", "source_url": "https://clinicaltrials.gov/study/NCT05173155", "start_date": "2022-05-30", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Total Hip Arthroplasty Versus Bipolar Hemiarthroplasty for Treatment of Intracapsular Displaced Fracture Neck Femur in Elderly Active Patients", "completion_date": "2026-01-15", "conditions": [ "Displaced Fracture Neck Femur", "Total Hip Arthroplasty (THA)", "Bipolar Hemiarthroplasty", "Elderly Active Patients" ], "countries": [ "Egypt" ], "curation_reason": "Total hip arthroplasty versus bipolar hemiarthroplasty; title uses the identity variant 'fracture neck femur'.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 342, "evidence_id": "4e22b3590d46c4c9", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* bedridden, immobile, or cognitively impaired patients", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 287 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 342, "evidence_id": "46188b517524f8d0", "matched_rule": "\\bbedridden\\b", "quote": "* bedridden, immobile, or cognitively impaired patients", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 287 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* were aged \u2265 65 years\n* with a displaced intracapsular fracture of the femoral neck (Garden type III, IV).\n\nExclusion Criteria:\n\n* extracapsular fracture of the femoral neck\n* Pathological fractures, or open fractures\n* Active infections at or near the hip joints.\n* bedridden, immobile, or cognitively impaired patients\n* patients with associated pelvic or acetabular fractures", "eligibility_sha256": "34ac26eb42e45884c4f7cdfe8599a052e29cdc80d38270dcea4d911692d4698d", "enrollment": 40, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Total Hip Arthroplasty", "Bipolar Hemiarthroplasty" ], "last_update_posted": "2026-02-17", "lead_sponsor": "Al-Azhar University", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT07409909", "official_title": "Total Hip Arthroplasty Versus Bipolar Hemiarthroplasty for Treatment of Intracapsular Displaced Fracture Neck Femur in Elderly Active Patients; Single-center Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "9809dbdc6679c81a55b5322d708b628923c51d3fa3f751b8a3eaad95bb8214a6", "source_url": "https://clinicaltrials.gov/study/NCT07409909", "start_date": "2023-01-02", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparative Study on Surgical Approaches for Elderly Femoral Neck Fractures", "completion_date": "2025-05-31", "conditions": [ "Function", "Pain" ], "countries": [ "China" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 330, "evidence_id": "fc304f5f738170b8", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "5. Able to walk independently and have intact cognitive function before the injury.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 247 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 190, "evidence_id": "fee3610a98a0e4cf", "matched_rule": "\\b(?:able to |can |cannot )?tolerate (?:surgery|the operation)\\b", "quote": "3. Patients who can tolerate surgery and agree to undergo surgery;", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 124 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 330, "evidence_id": "5855d279c4b3a32f", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "5. Able to walk independently and have intact cognitive function before the injury.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 247 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Age \u2265 80 years old;\n2. Diagnosed with unilateral femoral neck fracture through imaging examination;\n3. Patients who can tolerate surgery and agree to undergo surgery;\n4. Undergoing hemiarthroplasty (HA) for the first time;\n5. Able to walk independently and have intact cognitive function before the injury.\n\nExclusion Criteria:\n\n1. Bilateral femoral neck fractures;\n2. Patients with pathological fractures;\n3. Hip dysplasia, rheumatoid osteoarthritis, or other hip disorders;\n4. Patients with systemic or localized infections or inflammatory reactions at the surgical site;\n5. Patients with other lower limb fractures or severe injuries to other parts of the body; Patients with a history of previous hip surgery.", "eligibility_sha256": "61e5699272b0afc811d29f107c7ded78e8523bd57196294c73700fd6df6dbecf", "enrollment": 102, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Direct anterior approach hemiarthroplasty", "Posterior lateral approach hemiarthroplasty" ], "last_update_posted": "2025-06-11", "lead_sponsor": "Fujian Provincial Hospital", "masking": null, "maximum_age": null, "minimum_age": "80 Years", "nct_id": "NCT06760949", "official_title": "A Single Center Prospective Controlled Study of Direct Anterior Approach and Posterior Lateral Approach in the Treatment of Femoral Neck Fractures in Elderly Patients", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "3bd35f64ed23b6b0b82dc5d5bf4928db75acfc0f8a97d97a37a3f14a07dd8858", "source_url": "https://clinicaltrials.gov/study/NCT06760949", "start_date": "2023-02-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Minimally Displaced Femoral Neck Fracture Pilot Study", "completion_date": "2026-12", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Canada", "Spain", "United States" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 528, "evidence_id": "b8becc5268339a37", "matched_rule": "\\binformed consent\\b", "quote": "* Informed consent obtained from patient or proxy.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 478 }, { "effect": "restrictive", "end": 1331, "evidence_id": "00e7922042b99436", "matched_rule": "\\binformed consent\\b", "quote": "* Unable to obtain informed consent due to language barriers.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1270 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mixed" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 1186, "evidence_id": "85f8edaf3cea2b55", "matched_rule": "\\btoo ill\\b", "quote": "* Patient is too ill, in the judgement of the attending surgeon, for internal fixation.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1099 }, { "effect": "restrictive", "end": 1269, "evidence_id": "6dd62c50a294174c", "matched_rule": "\\btoo ill\\b", "quote": "* Patient is too ill, in the judgement of the attending surgeon, for arthroplasty.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1187 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [ { "effect": "restrictive", "end": 1331, "evidence_id": "bcbe59477cd8eff6", "matched_rule": "\\blanguage barriers?\\b", "quote": "* Unable to obtain informed consent due to language barriers.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1270 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "restrictive" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 798, "evidence_id": "aa6c9eca85017fca", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* Unable to ambulate 10 feet pre-injury with any assistance.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 738 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients 60 years of age or older.\n* Complete fracture of the femoral neck (AO/OTA 31B) confirmed with anteroposterior and lateral hip radiographs, computed tomography, or magnetic resonance imaging (MRI).\n* Minimally displaced fracture that could be, in the judgment of the attending surgeon, optimally managed with either arthroplasty or in situ internal fixation without reduction.\n* Low energy injury mechanism defined as a fall from standing height.\n* Informed consent obtained from patient or proxy.\n* Surgeons with expertise in total hip arthroplasty, hemiarthroplasty, and internal fixation are available to perform surgery. Note: Surgeons do not need to be experts in all techniques.\n\nExclusion Criteria:\n\n* Unable to ambulate 10 feet pre-injury with any assistance.\n* Associated lower extremity injury that prevents post-operative weightbearing.\n* Retained hardware around the hip that precludes either study treatment.\n* Infection around the hip (soft tissue or bone).\n* Pathologic fracture with a lytic lesion in the femoral neck that precludes internal fixation.\n* Patient is too ill, in the judgement of the attending surgeon, for internal fixation.\n* Patient is too ill, in the judgement of the attending surgeon, for arthroplasty.\n* Unable to obtain informed consent due to language barriers.\n* Problems, in the judgment of study personnel, with maintaining follow-up with the patient.\n* Currently enrolled in a study that does not permit co-enrollment.\n* Prior enrollment in the trial.\n* Other reason to exclude the patient, as approved by the Methods Centre.", "eligibility_sha256": "188e7dcbd0dac38dcd94d651cee0232eaa4c80a0b00e99c817e053db27b19c92", "enrollment": 40, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Arthroplasty", "Internal Fixation" ], "last_update_posted": "2026-02-13", "lead_sponsor": "University of Maryland, Baltimore", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT05947058", "official_title": "Multicenter Randomized Controlled Trial Comparing Hip Arthroplasty to Internal Fixation for Minimally Displaced Femoral Neck Fractures: A Pilot Study", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "55afebebda2f0dd42e7fdab2ab7c6496f9907893885c3e33f090d816f6a35384", "source_url": "https://clinicaltrials.gov/study/NCT05947058", "start_date": "2023-11-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Femoral Neck Locking Plate Vs Multiple Cannulated Cancellous Screws in Treatment of Femoral Neck Fractures in Young Adults: Randomized Controlled Clinical Trial Study", "completion_date": "2025-01-01", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Egypt" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 148, "evidence_id": "b0687668be44b5ae", "matched_rule": "\\b(?:i|in)dependent walker\\b", "quote": "* idependent walker before trauma without any aids", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 98 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "a9509fb2033351d1", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 55 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* patients (20-55) years\n* having unilateral traumatic femoral neck fracture\n* idependent walker before trauma without any aids\n\nExclusion Criteria:\n\n* open fracture\n* pathological fracture\n* preexisting deformity\n* other pelvic or ipsilateral femoral injuries\n* renal impairment or were on high dose steroids", "eligibility_sha256": "bf186642d1e67c497d0c34978c733447bbeddb7b7c58b5ec9548d4d5e55f0fb8", "enrollment": 20, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "femoral neck locking plate", "multiple cannulated cancellous screws" ], "last_update_posted": "2023-12-19", "lead_sponsor": "Eslam Mohamed AHmed", "masking": null, "maximum_age": "55 Years", "minimum_age": "20 Years", "nct_id": "NCT06162637", "official_title": "Femoral Neck Locking Plate Vs Multiple Cannulated Cancellous Screws in Treatment of Femoral Neck Fractures in Young Adults: Randomized Controlled Clinical Trial Study", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "71b0ccf91d42c3328237b460acba3a0a9521e2db764a1dbcb0bfafb55dfcbad0", "source_url": "https://clinicaltrials.gov/study/NCT06162637", "start_date": "2024-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Open Reduction in Femoral Neck Fractures", "completion_date": "2027-03-30", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Egypt" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "d7024f6a265039ef", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 60 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* patients of both genders between the ages of 16 to 60 years old and had trauma caused femoral neck fracture.\n* patients of both genders with Garden's type three and four femoral neck fractures\n\nExclusion Criteria:\n\n* patients of both genders below the age of 16 and above 60 years old.\n* patients with pathological femoral neck fractures.\n* patients with autoimmune diseases like rheumatoid arthritis.\n* patients with neglected femoral neck fractures(more than 1 week).", "eligibility_sha256": "047e043db3959db683191659cec2161027ce8c699877b9e318fae0ba5c3bfbd8", "enrollment": 3, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Open reduction of femoral neck fractures and internal fixation by dynamic hip screws", "Open reduction of femoral neck fractures using watson jones or smith peterson approachand internal fixation by cannulated screws and medial buttress plate" ], "last_update_posted": "2025-03-12", "lead_sponsor": "Samer youssef mansour meglaa", "masking": null, "maximum_age": "60 Years", "minimum_age": "16 Years", "nct_id": "NCT06872970", "official_title": "Outcomes of Open Reduction and Internal Fixation of Femoral Neck Fractures Using Dynamic Hip Screw vs Cannulated Screws and Medial Buttress Plate", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "dea7b5638dd9618d48ae259be881fc14bee10d14425ff2d4f09a93e6647782e7", "source_url": "https://clinicaltrials.gov/study/NCT06872970", "start_date": "2024-04-12", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "The Hip Fracture Surgical Approach Trial", "completion_date": "2028-03-30", "conditions": [ "Hip Fracture", "Femoral Neck Fracture" ], "countries": [ "Norway" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 261, "evidence_id": "b52d52cac82e9a93", "matched_rule": "\\bexpected (?:injury )?survival\\b", "quote": "* Patients assessed to be in a terminal state with an expected survival of less than 1 week", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 170 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Femoral neck fracture\n* Clinical indication for hemiarthroplasty\n* Age over 50 years\n\nExclusion Criteria:\n\n* Previous hip implants in the same hip\n* Patients assessed to be in a terminal state with an expected survival of less than 1 week\n* Other factors that makes follow-up impossible", "eligibility_sha256": "7f342712197c7e6969fb1b577df99b212c93cb96351bd04fb2963adcf4a626ea", "enrollment": 476, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Direct lateral approach", "SPAIRE" ], "last_update_posted": "2026-03-30", "lead_sponsor": "Diakonhjemmet Hospital", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT06146205", "official_title": "The Hip Fracture Surgical Approach Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4f707a13859a5e2dbac5dae77b17b94c09712d79fb937d45213a4a1a4b31e321", "source_url": "https://clinicaltrials.gov/study/NCT06146205", "start_date": "2024-04-30", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Orthopedic Intelligent Navigation System in the Treatment of Fresh Femoral Neck Fractures", "completion_date": "2026-10-31", "conditions": [ "Fracture of Neck of Femur" ], "countries": [ "China" ], "curation_reason": "Navigation-assisted versus conventional screw placement missed by the initial lexicon.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 1318, "evidence_id": "584407b1b945a9d9", "matched_rule": "\\bmentally incapable\\b", "quote": "8. The patient is mentally incapable or unable to understand the requirements of participating in the study, and it is difficult to cooperate;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1176 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 343, "evidence_id": "80e874a3fc6d72e5", "matched_rule": "\\blegal representative\\b", "quote": "4. The subject or his legal representative is informed of the nature of the study and agrees to participate in the study.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 222 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 221, "evidence_id": "cf190b1c3204d63d", "matched_rule": "\\b(?:able to |can |cannot )?tolerate (?:surgery|the operation)\\b", "quote": "3. Patients with indications for internal fixation of femoral neck fracture and able to tolerate surgery;", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 116 }, { "effect": "restrictive", "end": 753, "evidence_id": "369bbd6ef6b9020b", "matched_rule": "\\b(?:able to |can |cannot )?tolerate (?:surgery|the operation)\\b", "quote": "3. Patients determined by researchers to be physically weak or unable to tolerate surgery due to other systemic diseases;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 632 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Age \u226518 years old, gender is not limited;\n2. Patients diagnosed with femoral neck fracture;\n3. Patients with indications for internal fixation of femoral neck fracture and able to tolerate surgery;\n4. The subject or his legal representative is informed of the nature of the study and agrees to participate in the study.\n\nExclusion Criteria:\n\n1. Participants who had participated in clinical studies of other drugs, biologics or medical devices before enrollment and did not reach the primary study endpoint time limit;\n2. The patient is known to have a history of allergy to one or more implanted materials;\n3. Patients determined by researchers to be physically weak or unable to tolerate surgery due to other systemic diseases;\n4. Active infection of the hip joint or other parts of the body is determined by the investigator;\n5. Diagnosed as metabolic bone disease, radiation bone disease, etc.;\n6. Severe hip contracture deformity or severe muscle loss fused to the functional position for a long time without pain;\n7. have inflammatory arthritis, such as rheumatoid arthritis, systemic lupus erythematosus arthritis, ankylosing spondylitis, etc.;\n8. The patient is mentally incapable or unable to understand the requirements of participating in the study, and it is difficult to cooperate;\n9. Other conditions deemed unsuitable for inclusion by the investigator.", "eligibility_sha256": "b982d7c09e482d3f382c96119c805daaad19bb3655253a2e7ce94b4af4999485", "enrollment": 300, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Three cannulated compression screws by navigation system", "Traditional three cannulated compression screws" ], "last_update_posted": "2024-12-03", "lead_sponsor": "Chinese PLA General Hospital", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT06713018", "official_title": "Prospective, Multicenter, Randomized Controlled Clinical Study of Orthopedic Intelligent Navigation System in the Treatment of Fresh Femoral Neck Fractures", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "NOT_YET_RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "04100052918f469e1b8203fb6edbd4712f595661615ba6a110ef287d1200d56f", "source_url": "https://clinicaltrials.gov/study/NCT06713018", "start_date": "2024-12-10", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures", "completion_date": "2026-10-31", "conditions": [ "Fracture of Neck of Femur" ], "countries": [ "China" ], "curation_reason": "Compression screws versus DCS/medial-support plate missed by the initial lexicon.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 1465, "evidence_id": "8e903b5c3a7ea6f9", "matched_rule": "\\bmental capacity\\b", "quote": "8. Patients who lack the mental capacity or understanding to meet the requirements of participating in the study, or are difficult to cooperate with;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1316 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 482, "evidence_id": "84938d52a8df4b99", "matched_rule": "\\blegal representatives\\b", "quote": "4. Participants or their legal representatives are informed about the nature of this study and agree to participate.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 366 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 850, "evidence_id": "21ed7920112d5004", "matched_rule": "\\bfrail(?:ty)?\\b", "quote": "3. Judged by the investigator as physically frail or unable to tolerate surgery due to other systemic diseases;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 739 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Age \\>= 18 years, gender not specified;\n2. Patients with femoral neck fractures who have not undergone surgery for more than 3 weeks, or patients with persistent non-union following internal fixation of femoral neck fractures;\n3. Have indications for internal fixation surgery for femoral neck fractures and are able to tolerate the surgery;\n4. Participants or their legal representatives are informed about the nature of this study and agree to participate.\n\nExclusion Criteria:\n\n1. Participants who have not reached the primary endpoint of other drug, biological agent, or medical device clinical trials prior to enrollment;\n2. Known history of hypersensitivity to one or more implanted materials by the patient;\n3. Judged by the investigator as physically frail or unable to tolerate surgery due to other systemic diseases;\n4. Active infectious foci in the hip joint or other parts of the body, as judged by the investigator;\n5. Diagnosed with metabolic bone disease, radiation-induced bone disease, etc.;\n6. Severe hip contracture deformity or severe muscle weakness that has been immobilized in functional position for a long time and painless;\n7. Suffering from inflammatory arthritis, such as rheumatoid arthritis, systemic lupus erythematosus arthritis, ankylosing spondylitis, etc.;\n8. Patients who lack the mental capacity or understanding to meet the requirements of participating in the study, or are difficult to cooperate with;\n9. Other situations where the investigator deems the participant unsuitable for inclusion.", "eligibility_sha256": "d3442a7fd18eb1858acfc6f02d5a4927c5e3f9e5537e83a50869476584b4bda5", "enrollment": 400, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "cannulated compression screws + iliac bone graft", "DCS + medial support plate + iliac bone graft" ], "last_update_posted": "2024-12-04", "lead_sponsor": "Chinese PLA General Hospital", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT06713031", "official_title": "Prospective, Multicenter, Randomized Controlled Clinical Study of Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "NOT_YET_RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "fde9b8d797bf88c405f19e8acedc8d1e3123a5acd7af0525c1f6346efe7a73e7", "source_url": "https://clinicaltrials.gov/study/NCT06713031", "start_date": "2024-12-10", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Clinical Study of a Novel Sliding Compression Locking Plate in the Treatment of Fresh Femoral Neck Fractures", "completion_date": "2026-10-31", "conditions": [ "Fracture of Femoral Neck" ], "countries": [ "China" ], "curation_reason": "Locking plate versus compression-screw comparison missed by the initial lexicon.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 1320, "evidence_id": "e1132fbf39292819", "matched_rule": "\\bmentally incapable\\b", "quote": "8. The patient is mentally incapable or unable to understand the requirements of participating in the study, and it is difficult to cooperate;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1178 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 345, "evidence_id": "ac706e6cc42fea98", "matched_rule": "\\blegal representative\\b", "quote": "4. The subject or his legal representative is informed of the nature of the study and agrees to participate in the study.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 224 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 223, "evidence_id": "41dafe3ba92cf859", "matched_rule": "\\b(?:able to |can |cannot )?tolerate (?:surgery|the operation)\\b", "quote": "3. Patients with indications for internal fixation of femoral neck fracture and able to tolerate surgery;", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 118 }, { "effect": "restrictive", "end": 755, "evidence_id": "573e579e71678070", "matched_rule": "\\b(?:able to |can |cannot )?tolerate (?:surgery|the operation)\\b", "quote": "3. Patients determined by researchers to be physically weak or unable to tolerate surgery due to other systemic diseases;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 634 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Age \\>=18 years old, gender is not limited;\n2. Patients diagnosed with femoral neck fracture;\n3. Patients with indications for internal fixation of femoral neck fracture and able to tolerate surgery;\n4. The subject or his legal representative is informed of the nature of the study and agrees to participate in the study.\n\nExclusion Criteria:\n\n1. Participants who had participated in clinical studies of other drugs, biologics or medical devices before enrollment and did not reach the primary study endpoint time limit;\n2. The patient is known to have a history of allergy to one or more implanted materials;\n3. Patients determined by researchers to be physically weak or unable to tolerate surgery due to other systemic diseases;\n4. Active infection of the hip joint or other parts of the body is determined by the investigator;\n5. Diagnosed as metabolic bone disease, radiation bone disease, etc.;\n6. Severe hip contracture deformity or severe muscle loss fused to the functional position for a long time without pain;\n7. have inflammatory arthritis, such as rheumatoid arthritis, systemic lupus erythematosus arthritis, ankylosing spondylitis, etc.;\n8. The patient is mentally incapable or unable to understand the requirements of participating in the study, and it is difficult to cooperate;\n9. Other conditions deemed unsuitable for inclusion by the investigator.", "eligibility_sha256": "d13f771b7c6e322f6ab794ef334f2d597ca183203087021280c5b41b6a98aad6", "enrollment": 1150, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Sliding compression locking plate", "Three cannulated compression screws" ], "last_update_posted": "2026-04-02", "lead_sponsor": "Chinese PLA General Hospital", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT06713291", "official_title": "Prospective, Multicenter, Randomized Controlled Clinical Study of a Novel Sliding Compression Locking Plate in the Treatment of Fresh Femoral Neck Fractures", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "426d1a0cb1e90b960688a0ea217f40cc1cb5e9eff2e8334c9b1d391e5c5e8ac2", "source_url": "https://clinicaltrials.gov/study/NCT06713291", "start_date": "2024-12-10", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Open vs Closed Reduction in Femoral Neck Fractures Using Anterolateral vs Direct Lateral Approach", "completion_date": "2027-10-10", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Egypt" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "564678bd6607b777", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 60 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Inclusion criteria:\n* patients of both genders between the ages of 16 to 60 years old and had trauma caused femoral neck fracture.\n* patients of both genders with Garden's type three and four femoral neck fractures\n\nExclusion Criteria:\n\n* patients of both genders below the age of 16 and above 60 years old.\n* patients with pathological femoral neck fractures.\n* patients with autoimmune diseases like rheumatoid arthritis.\n* patients with neglected femoral neck fractures(more than 1 week).", "eligibility_sha256": "524c0f4b9fb620c54741466818bc405f5a1593355d6ee3e0e424df04310fdfc3", "enrollment": 3, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE", "PROCEDURE" ], "interventions": [ "Closed reduction of femoral neck fractures", "Open reduction of femoral neck fractures" ], "last_update_posted": "2025-12-23", "lead_sponsor": "Samer youssef mansour meglaa", "masking": null, "maximum_age": "60 Years", "minimum_age": "16 Years", "nct_id": "NCT07299370", "official_title": "Outcomes of Open vs Closed Reduction in Femoral Neck Fractures Using Dynamic Hip Screw", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "df4eaf3417fd000d96fc1f4195979e48d5ef77b5b88659454530fb1a3b5b6c28", "source_url": "https://clinicaltrials.gov/study/NCT07299370", "start_date": "2025-02-02", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Evaluation of Fracture Migration After Internal Fixation of Femoral Neck Fractures in Younger Adults: A Clinical RCT Using RSA", "completion_date": "2028-12", "conditions": [ "Femoral Neck Fractures", "Internal Fixation; Complications", "Hip Fractures" ], "countries": [ "Denmark" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 349, "evidence_id": "d6a517bcdb51a43a", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Cognitive impairment that hinders informed consent", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 297 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 349, "evidence_id": "53087f2971f50257", "matched_rule": "\\binformed consent\\b", "quote": "* Cognitive impairment that hinders informed consent", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 297 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 296, "evidence_id": "e4c6d71aa6b03ba0", "matched_rule": "\\bfrail(?:ty)?\\b", "quote": "* Clinical Frailty Scale \u22655, indicating mild to severe frailty prior to the fracture", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 212 }, { "effect": "restrictive", "end": 564, "evidence_id": "6ea6d595fe21d47b", "matched_rule": "\\bcomorbid(?:ity|ities)\\b", "quote": "* Comorbidities making the participant ineligible for internal fixation such as:", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 484 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [ { "effect": "restrictive", "end": 105, "evidence_id": "94f46baadb64d984", "matched_rule": "\\bspeak and read (?:Danish|Dutch|English|French|German|Italian|Norwegian|Spanish|Swedish)\\b", "quote": "* Ability to speak and read Danish", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 71 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "restrictive" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "80081da08946d4c7", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 65 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Femoral neck fracture (DS720)\n* Age 18-64 years\n* Ability to speak and read Danish\n* Willingness to participate\n\nExclusion Criteria:\n\n* Pathological, basicervical or transcervical fracture\n* Clinical Frailty Scale \u22655, indicating mild to severe frailty prior to the fracture\n* Cognitive impairment that hinders informed consent\n* Previous fracture in the ipsilateral femur\n* Patients who are unwilling or incapable of following post-operative care instructions.\n* Comorbidities making the participant ineligible for internal fixation such as:\n\n * Material sensitivity, documented or suspected\n * Active or suspected latent infection, sepsis or marked local inflammation in or around the surgical area\n * Compromised vascularity, inadequate skin or neurovascular status\n * Compromised bone stock that cannot provide adequate support and/or fixation of the device due to disease, infection or prior implantation\n * Other physical, mental, medical or surgical conditions that would preclude the potential benefit of surgery.", "eligibility_sha256": "6a4061c20a6baa2a53d9d52a86fdbe85a38160c2dee07cf1b320a11b05f1b9a8", "enrollment": 75, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Dynaloc implant", "Cannulated cancellous screws", "Sliding hip screw" ], "last_update_posted": "2026-01-27", "lead_sponsor": "Odense University Hospital", "masking": null, "maximum_age": "65 Years", "minimum_age": "18 Years", "nct_id": "NCT06521671", "official_title": "Evaluation of Femoral Neck Fracture Migration After Internal Fixation With an Angle Stable Implant Compared With Gold Standard Cannulated Cancellous Screws in Young Adults: Study Protocol for a Clinical RCT Using Radiostereometric Analysis", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4707a737e878c4e8d96d2b4558bbc52fa85956f498c1fc74df08209141f9db42", "source_url": "https://clinicaltrials.gov/study/NCT06521671", "start_date": "2025-06-16", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Artificial Intelligence-Assisted vs Surgeon-Planned Trajectories in Freehand Femoral Neck Screw Fixation", "completion_date": "2027-06-15", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "China" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 821, "evidence_id": "997b1f7e86367331", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Severe physical illnesses, cognitive problems (such as memory loss), or mental health conditions that may impair the ability to comply with medical instructions or attending scheduled follow-up appointments.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 612 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 333, "evidence_id": "8424cf0085f61dfd", "matched_rule": "\\binformed consent\\b", "quote": "* Capable of understanding the study procedures and providing informed consent;", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 254 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age \u2265 18 years;\n* Radiologically confirmed diagnosis of femoral neck fracture (displaced or non-displaced);\n* Scheduled to undergo internal fixation with cannulated screws as the initial treatment strategy during the study period;\n* Capable of understanding the study procedures and providing informed consent;\n* Willing and able to adhere to the prescribed postoperative follow-up schedule and rehabilitation instructions.\n\nExclusion Criteria:\n\n* Evidence of avascular necrosis of the femoral head on the affected side prior to surgery;\n* Inability to tolerate the surgical intervention;\n* Severe physical illnesses, cognitive problems (such as memory loss), or mental health conditions that may impair the ability to comply with medical instructions or attending scheduled follow-up appointments.", "eligibility_sha256": "3d99b6ed204258e0b0eddb3650e7a45f1307c390f849b59ab48dcdc42e75b292", "enrollment": 334, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "AI-Assisted Screw Path Planning", "Surgeon-Directed Screw Path Planning" ], "last_update_posted": "2025-11-17", "lead_sponsor": "Union Hospital, Tongji Medical College, Huazhong University of Science and Technology", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT06937138", "official_title": "Comparison of AI-Assisted vs Surgeon-Planned Trajectories in Freehand Femoral Neck Screw Fixation: A Multicenter Randomized Controlled Trial", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "13be658a0411ee15bc8c767a39af52a3cd59fb33469a3d83b2eb1eb8750790e6", "source_url": "https://clinicaltrials.gov/study/NCT06937138", "start_date": "2025-11-14", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)", "completion_date": "2030-01-31", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Canada", "Norway", "Spain", "United States" ], "curation_reason": "Passed every component of the transparent operative-candidate screen.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 966, "evidence_id": "1a9c7bf07bf0f48b", "matched_rule": "\\binformed consent\\b", "quote": "* Unable to obtain informed consent due to language barriers.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 905 }, { "effect": "restrictive", "end": 1065, "evidence_id": "2aa372c2ae76d5e4", "matched_rule": "\\binformed consent\\b", "quote": "* Unable to obtain informed consent because the legally authorized representative was unavailable.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 967 }, { "effect": "restrictive", "end": 1430, "evidence_id": "a900dae0cd33a8c8", "matched_rule": "\\binformed consent\\b", "quote": "* Patient or legally authorized representative did not provide informed consent (declined participation).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1325 }, { "effect": "restrictive", "end": 1555, "evidence_id": "1cc0ff474b24fec2", "matched_rule": "\\blegally authorized representative\\b", "quote": "* Eligible patient or legally authorized representative was not approached within the screening window (missed participant).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1431 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 2080, "evidence_id": "7c1c7c5541019f18", "matched_rule": "\\btoo ill\\b", "quote": "* Patient is too ill, in the judgment of the attending surgeon, for internal fixation.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1994 }, { "effect": "restrictive", "end": 2162, "evidence_id": "9d293b5b9531f218", "matched_rule": "\\btoo ill\\b", "quote": "* Patient is too ill, in the judgment of the attending surgeon, for arthroplasty.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 2081 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [ { "effect": "restrictive", "end": 966, "evidence_id": "804699d9237d446c", "matched_rule": "\\blanguage barriers?\\b", "quote": "* Unable to obtain informed consent due to language barriers.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 905 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "restrictive" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 821, "evidence_id": "9367447e2dd71136", "matched_rule": "\\bexpected (?:injury )?survival\\b", "quote": "* Expected injury survival of less than 12 months.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 771 }, { "effect": "restrictive", "end": 887, "evidence_id": "8b8a935b929b3f5a", "matched_rule": "\\bexpected (?:injury )?survival\\b", "quote": "* Terminal illness with expected survival of less than 12 months.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 822 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 1721, "evidence_id": "8c1e00a489d4e63b", "matched_rule": "\\bweight[- ]bearing\\b", "quote": "* Associated lower extremity injury that prevents post-operative weight-bearing.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1641 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* 60 years of age or older undergoing surgery due to a minimally displaced femoral neck fracture\n* The patient has a health condition affecting physical mobility.\n* Complete fracture of the femoral neck (AO/OTA 31B) confirmed with anteroposterior and lateral hip radiographs, computed tomography, or magnetic resonance imaging.\n* Minimally displaced fracture that could be, in the judgment of the attending surgeon, managed with either arthroplasty or in situ internal fixation without reduction.\n* Low energy injury mechanism.\n* Surgeons with expertise in internal fixation and total hip arthroplasty or hemiarthroplasty are available to perform surgery.\n\nExclusion Criteria:\n\n* The patient is not clinically suitable for either compared treatment.\n* Expected injury survival of less than 12 months.\n* Terminal illness with expected survival of less than 12 months.\n* Incarceration.\n* Unable to obtain informed consent due to language barriers.\n* Unable to obtain informed consent because the legally authorized representative was unavailable.\n* Problems, in the judgment of the study personnel, with maintaining follow-up with the patient.\n* Currently enrolled in a study or intervention domain that does not permit co-enrollment.\n* Prior enrollment in the specific platform trial intervention domain.\n* Patient or legally authorized representative did not provide informed consent (declined participation).\n* Eligible patient or legally authorized representative was not approached within the screening window (missed participant).\n* Other reasons to exclude the patient, as approved by the data coordinating center.\n* Associated lower extremity injury that prevents post-operative weight-bearing.\n* Retained hardware around the hip that precludes either study treatment.\n* Infection around the hip (soft tissue or bone).\n* Pathologic fracture with a lytic lesion in the femoral neck that precludes internal fixation.\n* Injury did not occur within 21 days of screening.\n* Patient is too ill, in the judgment of the attending surgeon, for internal fixation.\n* Patient is too ill, in the judgment of the attending surgeon, for arthroplasty.", "eligibility_sha256": "05a932ea398f11f5dcfbb45591cb11e9be662e2d32978d32e2ab9cf3cbcb6e5f", "enrollment": 600, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Hip arthroplasty", "Internal fixation" ], "last_update_posted": "2026-08-10", "lead_sponsor": "University of Southern California", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT07244211", "official_title": "Musculoskeletal Adaptive Platform Trial (MAPT): Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "RECRUITING", "primary_candidate": true, "primary_purpose": null, "record_role": "primary_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "e9492a5d247738ff15f8603c8adfb26c6d654b766d56d520294182c766ecb9fd", "source_url": "https://clinicaltrials.gov/study/NCT07244211", "start_date": "2026-01-23", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Goal Directed Haemodynamic Treatment for Patients With Proximal Femoral Fracture", "completion_date": "2014-10", "conditions": [ "Femoral Fracture" ], "countries": [ "Sweden" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 206, "evidence_id": "2af7b9e7205e0f78", "matched_rule": "\\binformed consent\\b", "quote": "* Patient who have a witnessed or written informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 148 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 630, "evidence_id": "f310e8a7951983d2", "matched_rule": "\\blife expectancy\\b", "quote": "* Life expectancy less than 6 months and/or pathological fractures", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 564 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients (men and women) age \u2265 70 years\n* Patients\u00b4 scheduled for operation of proximal femoral fracture during office hours\n* Patient who have a witnessed or written informed consent\n\nExclusion Criteria:\n\nAny of the following is regarded as a criterion for exclusion from the study:\n\n* Concomitant medication with Lithium\n* Known allergy (or hypersensitivity) to Lithium, or components of the medical device\n* Weight \u2264 40 kg\n* Other conditions or symptoms preventing the subject from entering the study, according to investigators judgment\n* Life expectancy less than 6 months and/or pathological fractures\n* Not possible to insert arterial line.", "eligibility_sha256": "ef2b87f9231e7ba1ca0f27ca128aae02665c0c2accedac634299cb40653aee6f", "enrollment": 150, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "Goal directed haemodynamic treatment", "Routine fluid treatment" ], "last_update_posted": "2020-09-18", "lead_sponsor": "Karolinska Institutet", "masking": null, "maximum_age": null, "minimum_age": "70 Years", "nct_id": "NCT01141894", "official_title": "Evaluation of Costs and Consequences of Alternative Strategies of Intraoperative Fluid and Pharmacological Optimization. A Randomized Clinical Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "TERMINATED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "7389dde5a67b3d514e8c5b66189319b06bcd73c1fa5ac56f1786932657f84b39", "source_url": "https://clinicaltrials.gov/study/NCT01141894", "start_date": "2010-03", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "The Effect of Periarticular Multi-Drug Regimen on Pain After Partial Hip Replacement", "completion_date": "2012-04", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "South Korea" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* femoral neck fracture\n* partial hip replacement\n\nExclusion Criteria:\n\n* r/o infection\n* reoperation\n* mental change", "eligibility_sha256": "6f06abaf9af8b069ee9d69f6854b4e321ec64a4ff34f4173ce97b38e7e274336", "enrollment": 258, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "periarticular injection of multidrug regimen", "none of medication preoperatively and intraoperatively" ], "last_update_posted": "2011-06-27", "lead_sponsor": "Chung-Ang University Hospital", "masking": null, "maximum_age": null, "minimum_age": null, "nct_id": "NCT01112436", "official_title": "The Effect of Periarticular Injection of Multi-drug Regimen on Pain in Patient Receiving Partial Hip Replacement:Randomized Prospective Study.", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "b475aaa05b1d87f5ed28a59e96bd2eb8efa62b5b9691a2f035b35ed60c759ea2", "source_url": "https://clinicaltrials.gov/study/NCT01112436", "start_date": "2010-05", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Postoperative Pain Control After Hip Hemiarthroplasty: Intrathecal Morphine vs Periarticular Infiltration of Bupivacaine", "completion_date": "2011-04", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "Thailand" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 103, "evidence_id": "51e30a45e9fdb785", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA classification 1-3", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 79 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "f555ae29fde2b048", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* age between 18-90 years\n* Co-operative, able to use PCA\n* ASA classification 1-3\n* no contraindication for Spinal Anesthesia\n* patient acceptance for spinal anesthesia\n* body weight \\> 30 kg.\n* BMI between 20-35\n* no history of drug allergy, e.g. Local Anesthetics, Paracetamol, etc.\n\nExclusion Criteria:\n\n* age \\> 90 years\n* previous Hemiarthroplasty (the same site)\n* pathological fracture such as severe infection, bone cancer", "eligibility_sha256": "f55742fbe68159986f67ce4cef54654605f02693e54a61e2e0598b991fb58b3d", "enrollment": 10, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG", "OTHER" ], "interventions": [ "morphine", "control", "Bupivacaine" ], "last_update_posted": "2016-10-04", "lead_sponsor": "Mahidol University", "masking": null, "maximum_age": "90 Years", "minimum_age": "18 Years", "nct_id": "NCT01219062", "official_title": "Comparative of Postoperative Pain Control at 24 and 48 Hours Between Intrathecal 0.1 mg. of Morphine or Local Infiltration of 20 ml. of 0.25% Bupivacaine in Patients Post Hip Hemiarthroplasty Under Spinal Anesthesis", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "TERMINATED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5ef0a374bdf6ecbc6d3d78f1da539bc80f777ddca1fbaac92861feb64a9c2979", "source_url": "https://clinicaltrials.gov/study/NCT01219062", "start_date": "2010-09", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw", "completion_date": "2012-09", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Thailand" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 114, "evidence_id": "8d6d7066d382d815", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA class 1-3", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 99 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "cbe77de6ed9dd49b", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* 18-90 years old\n* good consciousness, well co-operated, can use PCA machine\n* ASA class 1-3\n* no contraindication of spinal anesthesia\n* accept for spinal anesthesia\n* body weight \\> 30 kg\n* BMI 20-35 kg/m2\n* no history of research-drug allergy\n\nExclusion Criteria:\n\n* previous history of hip surgery (the same side)\n* pathological fractured such as severe infection, bone cancer", "eligibility_sha256": "c7f91700dcb8f51da9139153f913255d6b6d7c1e8d3f2a137f77e9ea40cdb1a7", "enrollment": 80, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Bupivacaine, morphine" ], "last_update_posted": "2011-08-04", "lead_sponsor": "Mahidol University", "masking": null, "maximum_age": "90 Years", "minimum_age": "18 Years", "nct_id": "NCT01219088", "official_title": "Post Operative Pain Control Among Intrathecal 0.1 mg Morphine, Femoral Nerve Block, or Periarticular Infiltration of 20 mL of 0.25% Bupivacaine in Patients Post Intramedullary Hip Screw", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "feab1f28f86baeb7e1e27928ae5e43c5dc42a141aaff1a835959397bc7ffbab6", "source_url": "https://clinicaltrials.gov/study/NCT01219088", "start_date": "2010-09", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "TRAUMEEL for Pain After Fracture of Neck of Femur", "completion_date": null, "conditions": [ "Pain", "Fracture of Neck of Femur" ], "countries": [ "Israel" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 175, "evidence_id": "a7a744ddfb7aebaf", "matched_rule": "\\binformed consent\\b", "quote": "* Signature upon informed consent form", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 137 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients of either sex undergoing surgical correction of unilateral fracture of neck of hip.\n* Age over 18 years.\n* Signature upon informed consent form\n\nExclusion Criteria:\n\n* Participation in another clinical trial within 4 weeks prior to enrollment.\n* Refused to give verbal consent to the telephone interviews\n* Impossibility to be reached during the 14-17 days post operative\n* Inability to comply with the study protocol for any other reason\n* Previous major surgical procedure on ipsilateral hip.\n* Current use of analgesics for any other reason.\n* A history of chronic pain syndrome.\n* Abused legal or illicit drug use.\n* Hypersensitivity to botanicals of the Compositae family\n* Known sensitivity to paracetamol, codeine or tramadol.", "eligibility_sha256": "08583c558a048c019769c5848dff4fd0b2e6d09a291571dd5e4b2d113d1c551d", "enrollment": 224, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Traumeel S", "Placebo remedy" ], "last_update_posted": "2010-10-29", "lead_sponsor": "Shaare Zedek Medical Center", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT00307905", "official_title": "A Randomised, Double - Blind, Placebo Controlled Clinical Trial to Assess the Efficacy of the Homeopathic Medication TRAUMEEL S in Controlling Post-operative Pain After Fracture of Neck of Femur", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "WITHDRAWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "d198bdb352009be34bd8986d0a345c9caea38624ade55c2198783b4ce933609b", "source_url": "https://clinicaltrials.gov/study/NCT00307905", "start_date": "2011-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "AVANTAGE\u00ae RELOAD Double Mobility Acetabular Cup -Clinical Study", "completion_date": "2027-04-27", "conditions": [ "Primary Osteoarthritis", "Post-Traumatic Arthritis", "Inflammatory Joint Disease", "Femoral Neck Fracture", "Femoral Head Necrosis", "Sequelae From Previous Hip Surgery", "Osteotomies", "Congenital Hip Dysplasia" ], "countries": [ "France", "Slovenia" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 1144, "evidence_id": "8d50cf83cc0d3435", "matched_rule": "\\bdementia\\b", "quote": "* Dementia and inability to understand and follow instructions", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1082 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Selection of subjects for this evaluation should be in accordance with the indications of the AVANTAGE\u00ae RELOAD with E1\u2122 or ArCom\u2122 liner specifically\n\n * Primary osteoarthritis\n * Post-Traumatic arthritis\n * Inflammatory joint disease (e.g. Rheumatoid arthritis)\n * Femoral neck fracture\n * Femoral head necrosis\n * Sequelae from previous hip surgery, osteotomies, etc.\n * Congenital hip dysplasia\n\nAdditional inclusion criteria include:\n\n* Male or female\n* 18 years of age or older\n* Subjects willing to return for follow-up evaluations\n* Subjects who read, understand study information and give written consent (specific local regulatory requirements)\n\nExclusion Criteria:\n\n* Exclusion criteria should be in accordance with Contraindications for the AVANTAGE\u00ae\n\nRELOAD:\n\nAbsolute contraindications include:\n\n* Infection\n* Sepsis\n* Severe muscular, neurological or vascular deficiencies of the extremity involved\n* Bone destruction or poor bone quality\n\nAdditional contraindications include:\n\n* Subjects unable to co-operate with and complete the study\n* Dementia and inability to understand and follow instructions\n* Neurological conditions affecting movement\n* Patient over 18 under law supervision", "eligibility_sha256": "1c61c453e771503a060df359dbc980cbc502a1749ce58575feb7d78750abdf6c", "enrollment": 500, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "Avantage Reload cup" ], "last_update_posted": "2024-11-14", "lead_sponsor": "Zimmer Biomet", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT03357445", "official_title": "Prospective, Multi Centre Evaluation of AVANTAGE\u00ae RELOAD Double Mobility Acetabular Cup - Clinical and Radiographic Outcomes", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "a4e2360e7bd127b1bfddf32025cb6be1beca35a74cc214d674558ca2b0ae6177", "source_url": "https://clinicaltrials.gov/study/NCT03357445", "start_date": "2011-10-14", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Intramedullary Nail Versus Sliding Hip Screw Inter-Trochanteric Evaluation", "completion_date": "2017-03", "conditions": [ "Femoral Neck Fractures", "Intertrochanteric Fracture" ], "countries": [ "Australia", "Canada", "China", "Colombia", "Denmark", "Germany", "Japan", "Netherlands", "Norway", "South Africa", "United Kingdom", "United States" ], "curation_reason": "Intertrochanteric-fracture trial with a noisy femoral-neck condition tag.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 1799, "evidence_id": "4900538ac960d7ac", "matched_rule": "\\bdementia\\b", "quote": "11. Patients with a previous history of frank dementia that would interfere with assessment of the primary outcome (i.e., EQ-5D at 1 year).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1660 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 805, "evidence_id": "3a902dd3cd7b629b", "matched_rule": "\\binformed consent\\b", "quote": "8. Provision of informed consent by patient or proxy.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 752 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 487, "evidence_id": "7a78282acb6aacd7", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "5. Patient was ambulatory prior to fracture, though they may have used an aid such as a cane or a walker.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 382 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Adult men or women aged 18 years and older (with no upper age limit).\n2. An intertrochanteric fracture (stable or unstable), AO Type 31-A1 or 31-A2, confirmed with anteroposterior and lateral hip radiographs, computed tomography, or magnetic resonance imaging (MRI).\n3. Low energy fracture (defined as a fall from standing height).\n4. No other major trauma.\n5. Patient was ambulatory prior to fracture, though they may have used an aid such as a cane or a walker.\n6. Anticipated medical optimization of the patient for operative fixation of the proximal femur.\n7. Operative treatment within 7 days after the trauma.(Operative treatment should take place as soon as possible as permitted by each institution's standard of care.)\n8. Provision of informed consent by patient or proxy.\n\nExclusion Criteria:\n\n1. Associated major injuries of the lower extremity (i.e., ipsilateral and/or contralateral fractures of the foot, ankle, tibia, fibula, or knee; dislocations of the ankle, knee, or hip).\n2. Retained hardware around the affected proximal femur.\n3. Infection around the proximal femur (i.e., soft tissue or bone).\n4. Patients with disorders of bone metabolism other than osteoporosis (i.e., Paget's disease, renal osteodystrophy, or osteomalacia).\n5. Patients with Parkinson's disease severe enough to increase the likelihood of falling or severe enough to compromise rehabilitation.\n6. Patients with a subtrochanteric fracture.\n7. Patients with a pathologic fracture.\n8. Patients with a reverse oblique fracture pattern, fracture AO Type 31-A3.\n9. Obesity in the judgment of the attending surgeon.\n10. Off-label use of the implant.\n11. Patients with a previous history of frank dementia that would interfere with assessment of the primary outcome (i.e., EQ-5D at 1 year).\n12. Likely problems, in the judgment of the Site Investigators, with maintaining follow-up. We will, for example, exclude patients with no fixed address, those who report a plan to move out of town in the next year, or intellectually challenged patients without adequate family support.\n13. Patient is enrolled in another ongoing drug or surgical intervention trial.\n14. If the attending surgeon believes that there is another reason to exclude this patient from INSITE. This reason will be documented on the case report forms (CRFs).", "eligibility_sha256": "5efc829c89ad60aedd026f0e56b452150386a8cdbac67bf34797e95de77ec053", "enrollment": 880, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Gamma3 Intramedullary Nails (Stryker)", "Sliding Hip Screws" ], "last_update_posted": "2019-03-07", "lead_sponsor": "Stryker Trauma and Extremities", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT01380444", "official_title": "A Multi-Center Randomized Controlled Trial of Intramedullary Nails Versus Sliding Hip Screws in the Management of Intertrochanteric Fractures of the Hip", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4a023f36cdaeb5d4d7abdb34578716c2b36a793272a13022ed45a990a4af6e10", "source_url": "https://clinicaltrials.gov/study/NCT01380444", "start_date": "2011-12", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparing Weight Bearing After Intramedullary Fixation Devices for the Proximal Femur Fracture", "completion_date": "2012-09", "conditions": [ "Closed Comminuted Oblique Intertrochanteric Fracture of Neck of Right Femur", "Closed Comminuted Oblique Intertrochanteric Fracture of Neck of Left Femur" ], "countries": [ "Israel" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 237, "evidence_id": "8cdc6f9efac6c158", "matched_rule": "\\bdementia\\b", "quote": "* dementia", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 227 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 120, "evidence_id": "9403282aad645eba", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* ambulatory patient, without support prior to the fall", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 65 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* pertrochanteric fracture ao 2.2 and above\n* ambulatory patient, without support prior to the fall\n* minor trauma mechanism\n* without other injuries\n* operated 3 days from the injury\n\nExclusion Criteria:\n\n* dementia\n* s/p hip or knee arthroplasty\n* known osteoarthritis", "eligibility_sha256": "e75ec35b3194f8e35818e421fa9cd368c48c9188e3cfad34a91ec25a49c85936", "enrollment": 100, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "PFNA proximal femur nail device (Synthes)", "INTERTAN proximal femur nail device (Smith&Nephew)" ], "last_update_posted": "2012-01-13", "lead_sponsor": "Rabin Medical Center", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT01509859", "official_title": "Prospective Randomized Trial Comparing the Weight Bearing After Fixation of Proximal Femur Fractures With Two Different Proximal Intramedullary Devices", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "19e18778178a304b4d56e9cf3f3e1bcad8ab02858e9aba12a8b8346508da581d", "source_url": "https://clinicaltrials.gov/study/NCT01509859", "start_date": "2011-12", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Second Study of the Effect of Teriparatide on Hip Fracture Healing", "completion_date": "2013-11", "conditions": [ "Femur Neck Fracture" ], "countries": [ "Belgium", "Croatia", "France", "Germany", "Greece", "Hungary", "India", "Netherlands", "Poland", "Romania", "South Korea", "Switzerland", "Turkey (T\u00fcrkiye)", "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 653, "evidence_id": "99e2fb5983b29ba2", "matched_rule": "\\binformed consent\\b", "quote": "* Have given written informed consent (participant or proxy) after being informed of the risks, medications, and study procedures", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 524 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 303, "evidence_id": "6686cc0b6c5c38db", "matched_rule": "\\blife expectancy\\b", "quote": "* Other than femoral neck fracture, be free of incapacitating conditions and have a life expectancy of at least 2 years", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 184 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "mentioned", "end": 183, "evidence_id": "2217b95ad9f2eaee", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* Community dwelling men and postmenopausal women who were ambulatory before sustaining a low-trauma, unilateral femoral neck fracture (displaced or nondisplaced)", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "mentioned" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Community dwelling men and postmenopausal women who were ambulatory before sustaining a low-trauma, unilateral femoral neck fracture (displaced or nondisplaced)\n* Other than femoral neck fracture, be free of incapacitating conditions and have a life expectancy of at least 2 years\n* Have received or are eligible for treatment with internal fixation (sliding hip screw or multiple cancellous screws) for the femoral neck fracture (the surgical procedure itself is not performed as part of this study)\n* Have given written informed consent (participant or proxy) after being informed of the risks, medications, and study procedures\n\nExclusion Criteria:\n\n* Increased baseline risk of osteosarcoma\n* History of unresolved skeletal diseases affecting bone metabolism other than primary osteoporosis\n* Abnormally elevated serum calcium at screening\n* Abnormally elevated serum intact parathyroid hormone (PTH) (1-84) at screening\n* Severe vitamin D deficiency at screening\n* Active liver disease or jaundice\n* Significantly impaired renal function\n* Abnormal thyroid function not corrected by therapy\n* History of malignant neoplasm in the 5 years prior to screening\n* History of bone marrow or solid organ transplantation\n* History of symptomatic nephrolithiasis or urolithiasis in the 1 year prior to screening\n* Previous treatment with the following bone active drugs is allowed but must be discontinued at screening: oral bisphosphonates, selective estrogen receptor modulators (SERMs), calcitonin, estrogen (oral, transdermal, or injectable), progestin, estrogen analog, estrogen agonist, estrogen antagonist or tibolone, and active vitamin D3 analogs. Androgen or other anabolic steroid use must be discontinued, except for use of physiologic replacement testosterone\n* Previous treatment with the following bone active drugs is exclusionary, if the stated treatment durations have been met: strontium ranelate for any duration, intravenous bisphosphonates in the 12 months preceding screening, and/or denosumab in the 6 months preceding screening\n* Prior treatment with PTH, teriparatide, or other PTH analogs, or prior participation in any other clinical trial studying PTH, teriparatide, or other PTH analogs\n* Local or systemic treatment with bone morphogenic proteins or any other growth factor\n* Previous fracture(s) or bone surgery in the currently fractured hip\n* Soft-tissue infection at the operation site\n* Treatment with bone grafting or osteotomies\n* Treatment with augmentation using any type of degradable cement, hydroxyapatite-coated implants, or with noninvasive interventions\n* Associated major injuries of a lower extremity including fractures of the foot, ankle, tibia, fibula, knee, femur, femoral head, or pelvis; dislocations of the ankle, knee, or hip", "eligibility_sha256": "2d40af5f4aa2996ecb5947607e6fb7ae209351ec4b8f488a70020e198f8ae885", "enrollment": 39, "enrollment_type": "ACTUAL", "has_results": true, "healthy_volunteers": null, "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG" ], "interventions": [ "Teriparatide", "Placebo", "Calcium supplementation", "Vitamin D supplementation" ], "last_update_posted": "2015-04-16", "lead_sponsor": "Eli Lilly and Company", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT01473602", "official_title": "Second Study of the Effect of Teriparatide on Femoral Neck Fracture Healing", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "62c81d59f52380655bcd717a98bdf0165f59a84943f6ae7fc5de05bfed8f8058", "source_url": "https://clinicaltrials.gov/study/NCT01473602", "start_date": "2012-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Prophylaxis of Deep Vein Thrombosis Following Total Hip Arthroplasty", "completion_date": "2013-01", "conditions": [ "Osteoarthritis, Hip", "Femur Head Necrosis", "Femoral Neck Fractures" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Male or female without childbearing potential aged \u226520 years who were scheduled for elective primary THA\n\nExclusion Criteria:\n\n* recent history of active bleeding or VTE\n* known genetic disorder associated with bleeding tendency or any condition related with an increased risk of bleeding\n* persistent blood pressure of \u2265160mmHg systolic and/or \u2265100 mmHg diastolic at baseline\n* myocardial infarction or cerebrovascular accident within three months of the scheduled surgery\n* major surgery in the prior three months\n* renal insufficiency with a creatinine clearance \\<60mL/min , hepatic failure combined with coagulopathy, or thrombocytopenia (platelets \\< 100,000/mm\u00b3), or planned indwelling epidural catheter for \\> 6 hours after the end of surgery", "eligibility_sha256": "62fb2a6389ff47bf00ee3783fb842704982ba05436fd60f9fc47faf52b9045db", "enrollment": 639, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG", "OTHER" ], "interventions": [ "Rivaroxaban", "Enoxaparin", "Normal saline" ], "last_update_posted": "2015-03-05", "lead_sponsor": "Samsung Medical Center", "masking": null, "maximum_age": null, "minimum_age": "20 Years", "nct_id": "NCT02379663", "official_title": "Efficacy and Safety for Prophylaxis of Deep Vein Thrombosis Following Total Hip Arthroplasty", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "0c7ce0279a3ad8339dd786f17aa33410a41b70aaf8c9c4089fcea3b41974f9c3", "source_url": "https://clinicaltrials.gov/study/NCT02379663", "start_date": "2012-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Effect of Teriparatide on Hip Fracture Healing", "completion_date": "2013-12", "conditions": [ "Femur Neck Fracture" ], "countries": [ "Australia", "Canada", "Denmark", "Estonia", "Finland", "Hong Kong", "India", "Israel", "Japan", "Latvia", "Lithuania", "New Zealand", "Norway", "Puerto Rico", "South Korea", "Spain", "Sweden", "Taiwan", "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 653, "evidence_id": "e39e442a8eafd45a", "matched_rule": "\\binformed consent\\b", "quote": "* Have given written informed consent (participant or proxy) after being informed of the risks, medications, and study procedures", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 524 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 303, "evidence_id": "6f522a6ce5f1cce0", "matched_rule": "\\blife expectancy\\b", "quote": "* Other than femoral neck fracture, be free of incapacitating conditions and have a life expectancy of at least 2 years", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 184 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "mentioned", "end": 183, "evidence_id": "0cc80153cf215af4", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* Community dwelling men and postmenopausal women who were ambulatory before sustaining a low-trauma, unilateral femoral neck fracture (displaced or nondisplaced)", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "mentioned" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Community dwelling men and postmenopausal women who were ambulatory before sustaining a low-trauma, unilateral femoral neck fracture (displaced or nondisplaced)\n* Other than femoral neck fracture, be free of incapacitating conditions and have a life expectancy of at least 2 years\n* Have received or are eligible for treatment with internal fixation (sliding hip screw or multiple cancellous screws) for the femoral neck fracture (the surgical procedure itself is not performed as part of this study)\n* Have given written informed consent (participant or proxy) after being informed of the risks, medications, and study procedures\n\nExclusion Criteria:\n\n* Increased baseline risk of osteosarcoma\n* History of unresolved skeletal diseases affecting bone metabolism other than primary osteoporosis\n* Abnormally elevated serum calcium at screening\n* Abnormally elevated serum intact parathyroid hormone (PTH) (1-84) at screening\n* Severe vitamin D deficiency at screening\n* Active liver disease or jaundice\n* Significantly impaired renal function\n* Abnormal thyroid function not corrected by therapy\n* History of malignant neoplasm in the 5 years prior to screening\n* History of bone marrow or solid organ transplantation\n* History of symptomatic nephrolithiasis or urolithiasis in the 1 year prior to screening\n* Previous treatment with the following bone active drugs is allowed but must be discontinued at screening: oral bisphosphonates, selective estrogen receptor modulators (SERMs), calcitonin, estrogen (oral, transdermal, or injectable), progestin, estrogen analog, estrogen agonist, estrogen antagonist or tibolone, and active vitamin D3 analogs. Androgen or other anabolic steroid use must be discontinued, except for use of physiologic replacement testosterone\n* Previous treatment with the following bone active drugs is exclusionary, if the stated treatment durations have been met: strontium ranelate for any duration, intravenous bisphosphonates in the 12 months preceding screening, and/or denosumab in the 6 months preceding screening\n* Prior treatment with PTH, teriparatide, or other PTH analogs, or prior participation in any other clinical trial studying PTH, teriparatide, or other PTH analogs\n* Local or systemic treatment with bone morphogenic proteins or any other growth factor\n* Previous fracture(s) or bone surgery in the currently fractured hip\n* Soft-tissue infection at the operation site\n* Treatment with bone grafting or osteotomies\n* Treatment with augmentation using any type of degradable cement, hydroxyapatite-coated implants, or with noninvasive interventions\n* Associated major injuries of a lower extremity including fractures of the foot, ankle, tibia, fibula, knee, femur, femoral head or pelvis; dislocations of the ankle, knee or hip", "eligibility_sha256": "5f299c11d7db278d7da719065cd44e17c5b6ec66fda57ca7604218218a9b5b38", "enrollment": 122, "enrollment_type": "ACTUAL", "has_results": true, "healthy_volunteers": null, "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG" ], "interventions": [ "Teriparatide", "Placebo", "Calcium supplementation", "Vitamin D supplementation" ], "last_update_posted": "2015-04-16", "lead_sponsor": "Eli Lilly and Company", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT01473589", "official_title": "Effect of Teriparatide on Femoral Neck Fracture Healing", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ed12b271a3d4369827ac3d60bf7221f3577b8bcf8be252d043dea225e6c59737", "source_url": "https://clinicaltrials.gov/study/NCT01473589", "start_date": "2012-02", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Multimodal Approach to Improve the Outcome of Patients With a Proximal Femoral Fracture", "completion_date": "2016-10-15", "conditions": [ "Proximal Femoral Fracture" ], "countries": [ "Germany" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 150, "evidence_id": "823aa7f548927d13", "matched_rule": "\\binformed consent\\b", "quote": "* written informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 124 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* proximal femoral fracture (femoral neck fracture/ pertrochanteric femoral fracture)\n* Age \u2265 60 years\n* written informed consent\n\nExclusion Criteria:\n\n* pathological fracture\n* multiple trauma\n* fracture during a hospital stay due to a different disease", "eligibility_sha256": "173cc060452f322a6d18a08527442d5211ec9f9f0bec6cfadf0ccf7ceb4e4678", "enrollment": 132, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "PulsioFlex\u00ae Monitoring" ], "last_update_posted": "2018-08-08", "lead_sponsor": "Technical University of Munich", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT01673776", "official_title": "Can a Multimodal Approach Improve the Outcome of Patients With a Proximal Femoral Fracture?", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "56a273dd735bedef17201b36dfcbe0e6710c6b62947f75ca19e9600e2526ffec", "source_url": "https://clinicaltrials.gov/study/NCT01673776", "start_date": "2012-03", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Internal Fixation of Hip Fractures Using Intraoperative Simultaneous Two Axis View", "completion_date": "2013-03", "conditions": [ "Fracture Neck of Femur" ], "countries": [ "Israel" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* patients with intertrochanteric femoral fracture who are going to be operated by closed reduction and internal fixation with an intramedullary nail.", "eligibility_sha256": "bba63ded6cd60733e010f9ce07530f0666d0fe892fd5a7806c70b6c43acd2fbf", "enrollment": 60, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "RADIATION" ], "interventions": [ "Imaging with two X-ray image intensifiers" ], "last_update_posted": "2012-09-05", "lead_sponsor": "Meir Medical Center", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT01524718", "official_title": null, "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5320e6293160d8c94ba78afac69e931e8c8ab9831aa0ebff5b4ea8507160503c", "source_url": "https://clinicaltrials.gov/study/NCT01524718", "start_date": "2012-09", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?", "completion_date": "2015-10", "conditions": [ "Hip Fracture" ], "countries": [ "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion criteria\n\n* AO/OTA (Orthopedic Trauma Association) fracture classification 31B\n* Surgically treated with either hemiarthroplasty or total hip arthroplasty\n* Acute fracture treated within 72 hours of injury\n* Low energy isolated injury\n* Age greater than 18 years old\n\nExclusion Criteria\n\n* Transfusion received during admission, prior to surgery\n* Creatinine clearance less than 30 mL/min\n* History of unprovoked Venous Thromboembolism (VTE) and/or recurrent VTE\n* Known history of Factor V Leiden, protein C/S deficiency, prothrombin gene mutation, anti-thrombin deficiency, anti-phospholipid antibody syndrome, lupus anticoagulant\n* Pregnancy or breastfeeding (pregnancy tests will be performed on all patients of child-bearing potential)\n* History of cerebrovascular accident (CVA), Myocardial infarction (MI), or VTE within the previous 30 days\n* Coronary stent placement within the previous 6 months\n* Disseminated intravascular coagulation\n* Subarachnoid hemorrhage", "eligibility_sha256": "38f2aff3e21e488c44400767a483226163c1ce5cd7cc3e870bb2915ca8ed8187", "enrollment": 138, "enrollment_type": "ACTUAL", "has_results": true, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "tranexamic acid", "placebo" ], "last_update_posted": "2018-11-14", "lead_sponsor": "Mayo Clinic", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT01714336", "official_title": "Is Tranexamic Acid Effective in Limiting Transfusion After Hip Replacement for Femoral Neck Fracture: A Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "1e8bda21e5be3a8e24928db8fc1a5d3f57aa55f820a8e0a8c3d989edff4dbfd5", "source_url": "https://clinicaltrials.gov/study/NCT01714336", "start_date": "2012-09", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Postoperative Analgesia for Fractured Neck of Femur With Periarticular Infiltration of Local Anaesthetic", "completion_date": "2013-06", "conditions": [ "Fractured Neck of Femur", "Postoperative Pain" ], "countries": [ "Ireland" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 213, "evidence_id": "65b4f734c5b4b985", "matched_rule": "\\bmini[- ]mental\\b", "quote": "* Mini mental scores less than 25", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 180 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 138, "evidence_id": "c68183d1963adc44", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA grade 1-3", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 123 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* patients scheduled for surgical fixation of fractured neck of femur\n* consent to spinal anaesthesia\n* ASA grade 1-3\n\nExclusion Criteria:\n\n* Patients refusal\n* Mini mental scores less than 25\n* Allergy to bupivacaine, morphine, paracetamol and diclofenac\n* Skin lessons/ infections at the site of injection\n* Uncorrected renal dysfunction\n* Coagulation disorders", "eligibility_sha256": "118c566cc6ae5f27cb1aae4df01d4ed9fd081162dce1939b44fed7405772db1c", "enrollment": 37, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Levobupivacaine infiltration group" ], "last_update_posted": "2014-02-07", "lead_sponsor": "Cork University Hospital", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT02057601", "official_title": "Postoperative Analgesia Following Surgery for Fractured Neck of Femur: a Comparison of Periarticular Infiltration of Local Anaesthetic With Systemic Postoperative Analgesics", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "712c38c72e15abd747bab386587e47b133290afd097a25f3725fb52ec175f2d2", "source_url": "https://clinicaltrials.gov/study/NCT02057601", "start_date": "2013-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Topical Application of Tranexamic Acid and Postoperative Blood Loss in Femoral Neck Fractures", "completion_date": "2017-11-03", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "Canada" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "aea2dc69b72a363c", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 95 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* hip fracture patients\n* aged 65 and older.\n\nExclusion Criteria:\n\n* bilateral femoral neck fracture patient and/or one that is not suited to a hemiarthroplasty repair.", "eligibility_sha256": "209eabe2d97d0490fc7436436bcfdb4798b9e467915ae5b13248a430153e743f", "enrollment": 15, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG", "OTHER" ], "interventions": [ "Tranexamic Acid", "placebo" ], "last_update_posted": "2018-11-30", "lead_sponsor": "Dr. Jeff Yach", "masking": null, "maximum_age": "95 Years", "minimum_age": "65 Years", "nct_id": "NCT01727843", "official_title": "Phase III Examining the Topical Application of Tranexamic Acid and Postoperative Blood Loss in Femoral Neck Fractures: a Randomized Control Trial.", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "TERMINATED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "a048b0f8a9ac2a8c0c4a25931fb8d9db3fde475ba0114a45b87dd1b390ff31a4", "source_url": "https://clinicaltrials.gov/study/NCT01727843", "start_date": "2013-04", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Rivastigmine Patch Effect on the Post-operative Delirium in Patients at Risk of Dementia.", "completion_date": "2015-04", "conditions": [ "Delirium" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 372, "evidence_id": "ecf43e44cfc0a340", "matched_rule": "\\bdementia\\b", "quote": "* Their Korean version MMSE(minimental status examination) are over 25, or global dementia scale (GDS) are under 3 or over 5.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 247 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 153, "evidence_id": "298c25b825dbdaa2", "matched_rule": "\\binformed consent\\b", "quote": "* Patients agree to the informed consent.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 112 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Consecutively enrolled the patients who is going to operation after femur neck fracture.\n* Patients agree to the informed consent.\n\nExclusion Criteria:\n\n* depressive mood and their geriatric depression scale is over 6 / 15.\n* Their Korean version MMSE(minimental status examination) are over 25, or global dementia scale (GDS) are under 3 or over 5.\n* any delirious state at pre-operation period by DSM IV and CAM (Confusion Assessment Method)", "eligibility_sha256": "0231fffcebecf40864d86a269e38ddfe78d2c231763085618375a09380c375db", "enrollment": 62, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Rivastigmine patch" ], "last_update_posted": "2015-04-10", "lead_sponsor": "Chung-Ang University Hospital", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT02413554", "official_title": "Rivastigmine Patch Effect on the Post-operative Delirium Limited to Femur Neck Fracture Operation in Patients at Risk of Dementia.", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "f1c4119dfbb925907111c1a748adb0030fcb5aa4caaa8682890a852e616b56f0", "source_url": "https://clinicaltrials.gov/study/NCT02413554", "start_date": "2013-04", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Short-term Functional Recovery Between Early- and Late Bisphosphonate Treatment Following Hemiarthroplasty", "completion_date": "2017-10", "conditions": [ "Osteoporotic Fractures", "Femoral Neck Fracture" ], "countries": [ "Thailand" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 1234, "evidence_id": "e9c64539fe86116c", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* The pre-injury functional status of the patients is non-ambulatory", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1166 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patient diagnosed with femoral neck fracture and was treated with bipolar hemiarthroplasty\n* Age more than 50 years old and bone mineral density (BMD) was in osteoporotic (T-score less than -2.5) or osteopenic (T-score between -1.0 and -2.5) ranges\n\nExclusion Criteria:\n\n* Patients who were treated with bipolar hemiarthroplasty for more than 2 weeks\n* Patients with postoperative complications which affect the postoperative rehabilitation program e.g. intraoperative cracking or fracture, postoperative cardiac complication\n* Have contraindications for bisphosphonates use e.g. renal insufficiency (glomerular filtration rate (GFR) \\< 30 ml/min), allergy to bisphosphonates, severe esophagitis, gastroesophageal reflux disease etc.\n* Patients with conditions/disorders which have an affect on bone mineral density or bone metabolism e.g. renal insufficiency, rheumatoid arthritis, Paget's disease, renal osteodystrophy, hyperparathyroidism, glucocorticoids use etc.\n* History of bisphosphonates use within 12 months\n* Open fracture, multiple fracture or multiple trauma patients\n* Pathological fracture\n* Bilateral lower extremity fractures\n* The pre-injury functional status of the patients is non-ambulatory", "eligibility_sha256": "f0d361453dce1eb8bb6c42f4c0c63e934406e6e70876483e9fb2208c065b7d6e", "enrollment": 86, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Risedronate" ], "last_update_posted": "2016-09-14", "lead_sponsor": "Mahidol University", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT02148848", "official_title": "A Comparative Study of Short-term Functional Recovery Between Early- and Late Bisphosphonate Treatment Following Hemiarthroplasty in Patients With Osteoporotic Femoral Neck Fractures", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "f62efb1fb106317f9d84827abc00cd5f0a8ec30560595d15b67b7668dd161b6a", "source_url": "https://clinicaltrials.gov/study/NCT02148848", "start_date": "2013-06", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty", "completion_date": "2014-06", "conditions": [ "Femoral Neck Fractures", "Postoperative Complications", "Inflammatory Response", "Postoperative Delirium", "Postoperative Cognitive Dysfunction" ], "countries": [ "China" ], "curation_reason": "Randomized contrast is dexmedetomidine versus saline; hemiarthroplasty is shared background care.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "mentioned", "end": 216, "evidence_id": "8a0b388ff9d15e30", "matched_rule": "\\bMoCA\\b", "quote": "* MoCA being more than 23", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 191 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "mentioned" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 190, "evidence_id": "08d3a198bf0df863", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* American Society of Anesthesiologists (ASA) physical status II-IV", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 123 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion criteria\n\n* Age \\> 75years old\n* Patients with femoral neck fractures\n* Undergoing hip hemi-arthroplasty surgery\n* American Society of Anesthesiologists (ASA) physical status II-IV\n* MoCA being more than 23\n\nExclusion Criteria\n\n* Patient refusal to participate in the study\n* Patient refusal or failure of regional block\n* allergic to local anesthetics or general anesthetics\n* history of opioid dependence\n* contraindications to nerve blocks (coagulation defects, infection at puncture site, preexisting neurological deficits in the lower extremities)\n* current severe psychiatric disease or alcoholism or drug dependence\n* severe visual or auditory disorder", "eligibility_sha256": "1680cdc6188312dd5497ec00831c97eb71867bb84bec437ea23ba532d996a749", "enrollment": 80, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG", "PROCEDURE" ], "interventions": [ "hip arthroplasty", "Total Intravenous Anesthesia and Peripheral nerve blocks" ], "last_update_posted": "2013-09-10", "lead_sponsor": "Chinese PLA General Hospital", "masking": null, "maximum_age": null, "minimum_age": "75 Years", "nct_id": "NCT01934049", "official_title": "The Effect of Dexmedetomidine on Postoperative Recovery in Elderly Patients With Femoral Neck Fracture Undergoing Hip Hemi-arthroplasty", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "1f641e230f1df15cd708825dee876d1ba982892b26583b42134ad773b7d5bd58", "source_url": "https://clinicaltrials.gov/study/NCT01934049", "start_date": "2013-09", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Periprosthetic Bone Remodeling in Femoral Neck Fracture Patients; a 5-year Follow up Study", "completion_date": "2020-03-25", "conditions": [ "Bone Mineral Density", "Femoral Neck Fractures" ], "countries": [ "Norway" ], "curation_reason": "Likely five-year follow-up of the NCT02028468 approach trial based on sponsor, start timing, arms, and follow-up framing; requires trial-family confirmation.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 128, "evidence_id": "49bf0a9b8e833878", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Intact cognitive function", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 101 }, { "effect": "restrictive", "end": 227, "evidence_id": "7910630ab6e283a5", "matched_rule": "\\bdementia\\b", "quote": "* Dementia", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 217 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 194, "evidence_id": "8be73d2951431625", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Ability to walk with or without a walking aid prior to falling.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 129 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "bfa0a7b71933e11e", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients between 70 and 90 years of age with displaced femoral neck fractures\n* Intact cognitive function\n* Ability to walk with or without a walking aid prior to falling.\n\nExclusion Criteria:\n\n* Dementia\n* Fractures in pathologic bone\n* Patients not belonging to the hospital community\n* Patients with sepsis or local infection\n* Fracture not eligible to be treated with a hemiarthroplasty", "eligibility_sha256": "175c7a4bd791a46ce4311a1440a37359924cd65430abab97b583321939342918", "enrollment": 51, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "Dual-energy X-ray absorbtiometry to evaluate periprosthetic bone mineral density around an uncemented stem implanted using either lateral or anterolateral approach to the hip joint" ], "last_update_posted": "2020-03-26", "lead_sponsor": "Sorlandet Hospital HF", "masking": null, "maximum_age": "90 Years", "minimum_age": "70 Years", "nct_id": "NCT03753100", "official_title": "Periprosthetic Bone Remodeling in Femoral Neck Fracture Patients: a 5-year Follow up Study Addressing the Influence of Surgical Approach on Periprosthetic Bone Mineral Density.", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "linked_secondary", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "8b67f6abf288abd02c00ed2b5b782210676717f8ecaf1ccfe3d61ab7d3b320df", "source_url": "https://clinicaltrials.gov/study/NCT03753100", "start_date": "2014-02", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Uncemented Hemiarthroplasty, Radiological Features Comparing Lateral Versus Anterolateral Approach", "completion_date": "2018-07-31", "conditions": [ "Femoral Neck Fractures", "Hemiarthroplasty", "Heterotopic Ossification" ], "countries": [ "Norway" ], "curation_reason": "Secondary radiographic follow-up of an earlier randomized comparison, not an independent primary trial.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 128, "evidence_id": "01fc2517daefbcdf", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Intact cognitive function", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 101 }, { "effect": "restrictive", "end": 227, "evidence_id": "da273115b3cf4517", "matched_rule": "\\bdementia\\b", "quote": "* Dementia", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 217 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 194, "evidence_id": "e3951c8a4bb94982", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Ability to walk with or without a walking aid prior to falling.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 129 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "a449697b77519982", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients between 70 and 90 years of age with displaced femoral neck fractures\n* Intact cognitive function\n* Ability to walk with or without a walking aid prior to falling.\n\nExclusion Criteria:\n\n* Dementia\n* Fractures in pathologic bone\n* Patients not belonging to the hospital community\n* Patients with sepsis or local infection\n* Fracture not eligible to be treated with a hemiarthroplasty", "eligibility_sha256": "175c7a4bd791a46ce4311a1440a37359924cd65430abab97b583321939342918", "enrollment": 150, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Hemiarthroplasty" ], "last_update_posted": "2021-01-25", "lead_sponsor": "Sorlandet Hospital HF", "masking": null, "maximum_age": "90 Years", "minimum_age": "70 Years", "nct_id": "NCT03974698", "official_title": "Uncemented Hemiarthroplasty, Radiological Features Comparing Lateral Versus Anterolateral Approach: A Follow-up of a Randomized Controlled Trial.", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "linked_secondary", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "43b3994a1e03e6609e3acd6d6b765c355e84f902f70772ab3bc3b596026ec2e1", "source_url": "https://clinicaltrials.gov/study/NCT03974698", "start_date": "2014-02-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture", "completion_date": "2016-08", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "Switzerland" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "9696f86e47280330", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 99 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n\\- patients with femoral neck fracture in the emergency department\n\nExclusion Criteria:\n\n* presence of demencia\n* body weight less than 40kg\n* presence of a cancer or patients receiving chemotherapy\n* allergy to local anaesthetics", "eligibility_sha256": "e9da6e8c97de3008d9b4c274ba08057a31f9176bc87819e54164faf14d8e2470", "enrollment": 30, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Fascia iliaca block", "Sham injection" ], "last_update_posted": "2016-09-27", "lead_sponsor": "Centre Hospitalier Universitaire Vaudois", "masking": null, "maximum_age": "99 Years", "minimum_age": "18 Years", "nct_id": "NCT02433548", "official_title": "Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "47b3a9ee37ce3e0625fb04f4c59d0e3ba1c88e85ab49e7209f00553b96bfac7d", "source_url": "https://clinicaltrials.gov/study/NCT02433548", "start_date": "2014-10", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Fascia Iliaca Compartment Block for Proximal-end Femur Fractures", "completion_date": "2015-08", "conditions": [ "Proximal Femur Fractures" ], "countries": [ "Egypt" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "0d8799693da71a46", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* American Society of Anesthesiologist physical status I to III\n* Patients scheduled for fixation for proximal end femur fracture\n\nExclusion Criteria:\n\n* Patients refusal\n* Morbid obese patients (BMI\\>40)\n* Bleeding diathesis\n* Previous femoral bypass surgery\n* Inguinal hernia\n* Inflammation/infection over injection site\n* Peripheral neuropathy\n* Allergy to local anesthetics agents used.\n* Severely altered consciousness level\n* Psychiatric disorders\n* Polytrauma", "eligibility_sha256": "65f1765b016ca0a892f94fcd4feae70a17ac66122bbff7cea7f6d4aca1891cbb", "enrollment": 60, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE", "DRUG" ], "interventions": [ "Placebo", "Bupivacaine", "Ultrasound guided fascia iliaca compartment block", "Intrathecal medications (bupivacaine (15 mg) in conjunction with fentanyl 20 micrograms)" ], "last_update_posted": "2016-03-08", "lead_sponsor": "Mansoura University", "masking": null, "maximum_age": "80 Years", "minimum_age": "20 Years", "nct_id": "NCT02696915", "official_title": "Fascia Iliaca Compartment Block in Proximal End Femur Fractures, Does it Make a Difference?", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "196444f5a32894ec68ba6509124dc2cb260ffd2fbca5e774b7fbeadb30bed93f", "source_url": "https://clinicaltrials.gov/study/NCT02696915", "start_date": "2015-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Femur Transtrochanteric Fractures Treated With Dynamic Hip Screw and Calcium Sulfate Scaffold.", "completion_date": "2019-05-10", "conditions": [ "Proximal Femur Fracture" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "9cce1354df35f89b", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients between 65 and 80 years old\n* Patients classified as 31A1.3 and all 31A2 by the Orthopaedic Trauma Association classification system.\n\nExclusion Criteria:\n\n* Patients with stable hip fractures\n* Participants who do not accept the randomization process\n* patients who do not complete follow-up during the study", "eligibility_sha256": "2e8ebc6eb7128fa0267f6cd32ab25abed5697bf21e313c8304465790c00730f6", "enrollment": 36, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Study group with absorbable graft of tricalcium \u00df phosphate / calcium sulfate hemihydrate paste" ], "last_update_posted": "2021-10-25", "lead_sponsor": "Hospital Regional Tlalnepantla", "masking": null, "maximum_age": "80 Years", "minimum_age": "65 Years", "nct_id": "NCT05091359", "official_title": "Unstable Proximal Femur Transtrochanteric Fractures Treated With Dynamic Hip Screw and \u00df -Tricalcium Phosphate/ Hemihydrated Calcium Sulfate Graft Scaffold", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5f21327e9cfe03771b29f7ebc4392ddbe8884586784431bf08a45e734e4b7812", "source_url": "https://clinicaltrials.gov/study/NCT05091359", "start_date": "2015-04-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Project JAY THA Registration Study", "completion_date": "2016-11-01", "conditions": [ "Osteoarthritis", "Rheumatoid Arthritis", "Post-traumatic Arthritis", "Avascular Necrosis", "Developmental Dysplasia of the Hip", "Femoral Neck Fracture" ], "countries": [ "China" ], "curation_reason": "General total-hip device trial with mixed indications rather than a fracture-specific randomized cohort.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 2030, "evidence_id": "0b1c9889b851ebd4", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Subject has an emotional or neurological condition that would affect their ability or willingness to participate in the study (e.g. cognitive disorder, mental illness, mental retardation).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1840 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 516, "evidence_id": "aa02f59eaf924910", "matched_rule": "\\binformed consent\\b", "quote": "* Subject who is able to give voluntary, written informed consent to participate in the study and from whom consent has been obtained by signing and dating an EC-approved consent form.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 332 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 776, "evidence_id": "18097ede4bf3381d", "matched_rule": "\\blife expectancy\\b", "quote": "* Life expectancy of subject is over 2 years.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 731 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "a9260f29685ba25b", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 75 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Male or female subjects, aged between 50 and 75 years inclusive of Chinese ethnicity.\n* Subject presents with osteoarthritis, rheumatoid arthritis, post-traumatic arthritis, avascular necrosis of hip joint, developmental dysplasia of the hip, or femoral neck fracture requiring primary total hip replacement.\n* Subject who is able to give voluntary, written informed consent to participate in the study and from whom consent has been obtained by signing and dating an EC-approved consent form.\n* Subject who is able to understand this clinical study, co-operates with the investigational procedures and is willing to return to the hospital for all the required post-operative follow-ups for up to 12 months.\n* Life expectancy of subject is over 2 years.\n\nExclusion Criteria:\n\n* Bilateral hip disease with the anticipated need for bilateral hip implant during study participation (i.e., within the next 12 months).\n* Subject experienced prior joint replacement surgery on any major joint (hip, knee) in lower limb within the last 12 months.\n* Subject with developmental dysplasia of the hip of CROWE grade 3 or 4.\n* Subject has known or suspected metal sensitivity.\n* Subject is known to have insufficient bone stock resulting from conditions such as cancer, significant osteoporosis or metabolic bone disorders, which cannot provide adequate support and/or fixation to the prosthesis.\n* Subject is severely obese (BMI\\>35).\n* Subject had an active infection or sepsis (treated or untreated).\n* Subject has conditions that may compromise implant stability or postoperative recovery (i.e., Paget's or Charcot's disease, vascular insufficiency, muscular atrophy, uncontrolled diabetes, moderate to severe renal insufficiency, hip abduction muscle strength less than grade IV or complete loss, or neuromuscular disease).\n* Subject has an emotional or neurological condition that would affect their ability or willingness to participate in the study (e.g. cognitive disorder, mental illness, mental retardation).\n* Subject is immunosuppressed, has an autoimmune disorder, or an immunosuppressive disorder. For examples, subject is on immunosuppressive therapy (corticosteroid hormones in large amounts, cytotoxic drugs, antilymphocytic serum or irradiation in large doses) or has acquired immunodeficiency syndrome (AIDS).\n* Subject is known to be at risk for lost to follow-up, or failure to return for scheduled visits.\n* Subject was enrolled in another investigational drug, biologic, or device study in the last 12 months.\n* Subject is a woman who is pregnant or lactating\uff0cor intends to become pregnant during the course of the study.\n* Known alcohol and/or drug abuse", "eligibility_sha256": "212dd5d8ac7562fe14025ebd00bd4ed42d54c551dad302da16bda9349343be58", "enrollment": 100, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Delta PLUS Femoral Head + SL-TWIN Stem", "BIOLOX forte ball head + SL-PLUS Stem" ], "last_update_posted": "2017-11-14", "lead_sponsor": "Smith & Nephew Orthopaedics (Beijing) Limited", "masking": null, "maximum_age": "75 Years", "minimum_age": "50 Years", "nct_id": "NCT02347384", "official_title": "A Prospective, Randomized, Multicenter Clinical Study in Chinese Subjects to Compare the Safety and Efficacy of the Delta PLUS Femoral Head and SL-TWIN Stem With BIOLOX Forte Ball Head and SL-PLUS Stem in Total Hip Arthroplasty", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "0bec55a5ad9a5c03f2523229386480db66be6f3ea127598d333202a3794203d2", "source_url": "https://clinicaltrials.gov/study/NCT02347384", "start_date": "2015-04-20", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Porous Tantalum Rods Improve the Hip Joint Function of Patients With Avascular Necrosis of the Femoral Head", "completion_date": "2017-05", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "China" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 535, "evidence_id": "709ed06363ca7b1a", "matched_rule": "\\binformed consent\\b", "quote": "* Provision of signed informed consent to participate in the trial", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 469 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "9c0e51158004b322", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients with fracture nonunion as indicated by a clear fracture line 12 months after femoral neck fracture; avascular necrosis of the femoral head as shown by cystic degeneration, sclerosis, and uneven density on X-ray images and CT scans\n* Patients with avascular necrosis of the femoral head after femoral neck fracture surgery who underwent internal fixation between 1 January 2016 and 31 May 2017\n* Age 18-80 years\n* Any sex and nationality\n* Provision of signed informed consent to participate in the trial\n\nExclusion Criteria:\n\n* Poor general health\n* Chronic disease or history of surgery\n* Alcohol abuse or long-term use of hormone drugs\n* Unable or declines to cooperate with treatment and examination because of language and/or mental disorders\n* Unable or declines to cooperate with rehabilitation treatment because of mental and/or psychological disorders", "eligibility_sha256": "55f0239721aff9bf376da2ba60005bd8c396a1d3d5133e928620f2ffd8ae1a2b", "enrollment": 100, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE", "PROCEDURE" ], "interventions": [ "porous tantalum rod", "core decompression" ], "last_update_posted": "2016-08-24", "lead_sponsor": "Qinghai University", "masking": null, "maximum_age": "80 Years", "minimum_age": "18 Years", "nct_id": "NCT02877472", "official_title": "Porous Tantalum Rods Improve the Hip Joint Function of Patients With Avascular Necrosis of the Femoral Head After Femoral Neck Fracture Surgery: a Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "9136fa3dc9c4ef2bbba35dd917080e4f281bf97af79e97a53dcd9e7ed486ac3b", "source_url": "https://clinicaltrials.gov/study/NCT02877472", "start_date": "2015-05", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After Hip Hemiarthroplasty", "completion_date": "2018-05-13", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Norway" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* scheduled for hemiarthroplasty at St. Olavs Hospital\n* competent and willing to give consent\n* able to be mobilized in the PACU and in the trauma ward unit.\n\nExclusion Criteria:\n\n* contraindications for spinal anesthesia, Dexamethasone, Dolcontin or Acetaminophene\n* receiving general anesthesia\n* patients operated on with an approach different to standard direct lateral surgery\n* receiving osteosyntheses\n* receiving femoral block less than 4 hours before surgery", "eligibility_sha256": "56158990cde9a1cc8edeac4224a76f3f0a9bb1429a34d80598ed1978cb815ddf", "enrollment": 123, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Ropivacaine", "Epinephrine", "Saline" ], "last_update_posted": "2020-09-11", "lead_sponsor": "St. Olavs Hospital", "masking": null, "maximum_age": null, "minimum_age": null, "nct_id": "NCT02585011", "official_title": "Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After Hip Hemiarthroplasty", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "8725d6e14f617afdd7e5e7bafcf11b8d9723a44fb692a98491d5b77624abc114", "source_url": "https://clinicaltrials.gov/study/NCT02585011", "start_date": "2015-12", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Supernormal Oxygen Delivery for Elderly Surgical Patients", "completion_date": "2017-03", "conditions": [ "Femoral Fractures" ], "countries": [ "China" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 187, "evidence_id": "8f9030cf3f5634e7", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "2. American Society of Anaesthesiologists (ASA) physical status of III or VI", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 111 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Adult patients scheduled for proximal femur fracture (PFF) surgery at this institution\n2. American Society of Anaesthesiologists (ASA) physical status of III or VI\n3. Two or more risk factors according to risk index of Lee\n\nExclusion Criteria:\n\n1. Patient age \\< 70 yrs\n2. Ongoing myocardial infarct or ischemia\n3. Chronic haemodialysis\n4. Inability to cooperate in the study\n5. Patient refusal", "eligibility_sha256": "5df49495b03539fdab28ddffba4735ed14496e2873ddec955a504440b03737d8", "enrollment": 70, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "SV maximization", "supernormal DO2" ], "last_update_posted": "2017-02-16", "lead_sponsor": "Guangzhou First People's Hospital", "masking": null, "maximum_age": null, "minimum_age": "70 Years", "nct_id": "NCT02629250", "official_title": "A Randomized Controlled Study of Supernormal Oxygen Delivery Goal-directed Therapy for Elderly Patients Undergoing Proximal Femoral Surgery.", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "e08596889feaa5789cc7a259d69465ab0d2f9cfe31625ed6d5cde59c45f03799", "source_url": "https://clinicaltrials.gov/study/NCT02629250", "start_date": "2015-12", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Allogeneic Mesenchymal Stromal Cells in Elderly Patients With Hip Fracture", "completion_date": "2018-12", "conditions": [ "Femoral Neck Fracture" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 387, "evidence_id": "6ae0cbd469ed415f", "matched_rule": "\\bdementia\\b", "quote": "4. Dementia of any type.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 363 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 221, "evidence_id": "5164885c0fbf29d5", "matched_rule": "\\binformed consent\\b", "quote": "4. Written informed consent of the patient or family members.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 160 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "dfcf5567db2c7522", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 85 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Patient between70 and 85 years old\n2. Proximal femur fracture type 31A3 31a2 classification AO/ASIF.\n3. Deambulation prior to fracture.\n4. Written informed consent of the patient or family members.\n\nExclusion Criteria:\n\n1. Presence of implants at proximal femur level.\n2. Presence of local or systemic septic process.\n3. Septic arthritis.\n4. Dementia of any type.\n5. Hematological and biochemical analysis with significant alterations that contraindicate surgery.\n6. Patients with positive serology for HIV 1 and 2, Hepatitis B, Hepatitis C and syphilis.\n7. Neoplastic disease detected in the last five years or without complete remission.\n8. Immunosuppressive status.\n9. Patients who received corticosteroids in the 3 months prior to study initiation.\n10. Simultaneous participation in another clinical trial or treatment with another investigational product within 3 months prior to inclusion in the study.\n11. Other conditions or circumstances that may compromise the patient's participation in the study according to medical criteria.\n12. Patient refusal to be followed by a period that may exceed the clinical trial itself.", "eligibility_sha256": "c92384c3a7b58449d5cdce2599de1c5af2990fff097a2ca733ccc138db0df46c", "enrollment": 0, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG", "PROCEDURE" ], "interventions": [ "XCEL-MT-OSTEO-BETA", "Surgical treatment" ], "last_update_posted": "2017-03-17", "lead_sponsor": "Banc de Sang i Teixits", "masking": null, "maximum_age": "85 Years", "minimum_age": "70 Years", "nct_id": "NCT02630836", "official_title": "A Pilot Clinical Trial of ex Vivo Expanded Allogenic Adult Stem Cells Combined With Allogenic Human Bone Tissue (XCEL-MT-OSTEO-BETA) in Proximal Femur Fractures in Elderly Patients", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "WITHDRAWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "a2c88cf34930ebc53c1de754c24cc764ebd9e04a9c4910c2e19af4b2411be479", "source_url": "https://clinicaltrials.gov/study/NCT02630836", "start_date": "2015-12", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty", "completion_date": "2019-06-30", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients undergoing hip hemiarthroplasty surgery for a displaced femoral neck fracture\n\nExclusion Criteria:\n\n* History of hemophilia, history of deep vein thrombosis, history of pulmonary embolism, history of thrombophilia, history of chronic renal failure\n* Patients with coronary ischemia (active or within the past calendar year), patients who have suffered a myocardial infarction, undergone percutaneous coronary intervention, undergone coronary artery bypass grafting, or undergone any revascularization procedure within the past calendar year\n* Patients with active subarachnoid hemorrhage, acquired defective color vision, patients who sustained a pathologic fracture (fracture through a neoplastic lesion), or patients who are pregnant\n* Patients with a known allergy to tranexamic acid\n* Patients taking Warfarin, Dabigatran, Rivaroxaban, Apixaban, and Fresh Frozen Plasma", "eligibility_sha256": "8e21dceb687bf1426bfe283ca7c9e725ef0a2f2d12a38fd54f593e069d3a439c", "enrollment": 36, "enrollment_type": "ACTUAL", "has_results": true, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Tranexamic Acid", "Placebo (saline)" ], "last_update_posted": "2021-07-22", "lead_sponsor": "UConn Health", "masking": null, "maximum_age": null, "minimum_age": "55 Years", "nct_id": "NCT02664909", "official_title": "Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "8e60a6af425ef5f940afb555d6c21c88f9f13b799f2ac5755c9c10699e65b305", "source_url": "https://clinicaltrials.gov/study/NCT02664909", "start_date": "2016-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Trial of Focused Cardiac Ultrasound for Fractured Neck of Femur Surgery", "completion_date": "2018-01-26", "conditions": [ "Hip Fractures" ], "countries": [ "Australia" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients presenting with isolated, primary, non-metastatic fractured neck of femur, where surgery is expected within 48 hours after hospital admission will be recruited.\n\nExclusion Criteria:\n\n* Patients with prior hip surgery on the affected side, or where the cause is likely to be due to metastatic cancer, or where survival is unlikely in the 24 hours from admission will not be included.", "eligibility_sha256": "a408b83bfbe302ee1089967c5a63ae397e8d18211dd47b1fe957ae31b480b2df", "enrollment": 100, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "Focused cardiac ultrasound" ], "last_update_posted": "2018-05-02", "lead_sponsor": "University of Melbourne", "masking": null, "maximum_age": null, "minimum_age": null, "nct_id": "NCT02629484", "official_title": "A Pilot Study to Assess Feasibility, Compliance, Safety and Group Separation for a Multicentre Randomised Trial of Preoperative Focused Cardiac Ultrasound for Fractured Neck of Femur Surgery", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "d2206cf551107a02d241ed3f53c7c14dd0165692338fa670cd9d90dae4bef6bb", "source_url": "https://clinicaltrials.gov/study/NCT02629484", "start_date": "2016-02-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Study of A Special Vessel Subtype in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture", "completion_date": "2018-02", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "China" ], "curation_reason": "Bone-specimen vessel study; randomized groups are not operative strategies.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "f592111cf87df855", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 75 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Ages Eligible for Study: 65-75 Years\n2. Genders Eligible for Study: Woman\n3. Accepts Healthy Volunteers: NO\n4. Study Population: Female patients with hip fracture. -\n\nExclusion Criteria:\n\n1. Malignancy or benign ovarian cysts\n2. Known chronic or systemic diseases\n3. Hormone therapy in the previous 3 months\n4. Bone metabolism and drug therapy", "eligibility_sha256": "55addd854f951b2c4b55c90cea1cbedacb0fc170326d79af912028e50f7d2ed6", "enrollment": 30, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "total hip arthroplasty or proximal femoral nails" ], "last_update_posted": "2016-04-25", "lead_sponsor": "Second Affiliated Hospital of Soochow University", "masking": null, "maximum_age": "75 Years", "minimum_age": "60 Years", "nct_id": "NCT02750046", "official_title": "Collection of Bone Specimens for Testing of A Special Vessel Subtype", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "FEMALE", "source_sha256": "499e12731c9deafde95ea3ab2e7d7a99f46c2401363e2446d5597199b82fc1d6", "source_url": "https://clinicaltrials.gov/study/NCT02750046", "start_date": "2016-03", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Recovery of Physical Functioning After Hip Fracture", "completion_date": "2021-06-01", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Norway" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 645, "evidence_id": "ec382077a2d4bb0b", "matched_rule": "\\bmental status\\b", "quote": "* Patients unable to walk 10 meters with or without a walking aid prior to the fracture, have a score of less than 15 points on Minimal Mental Status Evaluation (MMS-E) in the acute phase, have a pathological fracture, life expectancies of less than three months, medical contraindications for training, or are incapable of understanding and speaking the Norwegian language.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 271 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 248, "evidence_id": "d4eddcf6c7a90f51", "matched_rule": "\\binformed consent\\b", "quote": "* Patients with an acute low-energy hip fracture (intracapsular, trochanteric or subtrochanteric) and treated surgically, \u2265 65 years of age, living in their own homes prior to the fracture, and able to give an informed consent.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [ { "effect": "restrictive", "end": 645, "evidence_id": "501e65cfad976abd", "matched_rule": "\\b(?:Danish|Dutch|English|French|German|Italian|Norwegian|Spanish|Swedish)(?:\\s+or\\s+[A-Za-z]+)?\\s+(?:fluency|literacy|language)\\b", "quote": "* Patients unable to walk 10 meters with or without a walking aid prior to the fracture, have a score of less than 15 points on Minimal Mental Status Evaluation (MMS-E) in the acute phase, have a pathological fracture, life expectancies of less than three months, medical contraindications for training, or are incapable of understanding and speaking the Norwegian language.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 271 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "restrictive" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 645, "evidence_id": "33655aaca59e4d30", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Patients unable to walk 10 meters with or without a walking aid prior to the fracture, have a score of less than 15 points on Minimal Mental Status Evaluation (MMS-E) in the acute phase, have a pathological fracture, life expectancies of less than three months, medical contraindications for training, or are incapable of understanding and speaking the Norwegian language.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 271 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients with an acute low-energy hip fracture (intracapsular, trochanteric or subtrochanteric) and treated surgically, \u2265 65 years of age, living in their own homes prior to the fracture, and able to give an informed consent.\n\nExclusion Criteria:\n\n* Patients unable to walk 10 meters with or without a walking aid prior to the fracture, have a score of less than 15 points on Minimal Mental Status Evaluation (MMS-E) in the acute phase, have a pathological fracture, life expectancies of less than three months, medical contraindications for training, or are incapable of understanding and speaking the Norwegian language.", "eligibility_sha256": "1828ea4f25a1d95d3b44e516d07edbd159bcf75e206e4c4c1e4d746e96bd8490", "enrollment": 140, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "Functional training program" ], "last_update_posted": "2021-04-19", "lead_sponsor": "Vestre Viken Hospital Trust", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT02780076", "official_title": "Recovery of Physical Functioning, Activity Level, and Quality of Life After Hip Fracture in the Fragile Elderly", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "108abad11b98abc7182844cb20e167e7f3e326f4cb6ff6f1f7071fd87d4bc691", "source_url": "https://clinicaltrials.gov/study/NCT02780076", "start_date": "2016-05-30", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Restrictive vs Liberal Transfusion Strategy on Cardiac Injury in Patients Undergoing Surgery for Fractured Neck Of Femur", "completion_date": "2019-06-01", "conditions": [ "Anemia", "Cardiac Event", "Kidney Injury", "Fractured Hip" ], "countries": [ "United Kingdom" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "mentioned", "end": 221, "evidence_id": "a44653e3670af7eb", "matched_rule": "\\bpalliative care\\b", "quote": "* Refusal of consent of patient (or consultee) Patient for palliative care.", "section": "unspecified", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 146 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "mentioned" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:Adults aged over 50 years Within 48 hours of admission to hospital with fractured Neck of Femur. Exclusion Criteria: Age \\<50\n\n* Refusal of consent of patient (or consultee) Patient for palliative care.", "eligibility_sha256": "93fe0aae3180784a1b39eb3b6bf18dbf534522eae78caad96f0d7861254af7c9", "enrollment": 200, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "BIOLOGICAL" ], "interventions": [ "Administration of Red Cell" ], "last_update_posted": "2020-03-11", "lead_sponsor": "NHS Lothian", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT03407573", "official_title": "The Impact of Restrictive Versus Liberal Transfusion Strategy on Cardiac Injury in Patients Undergoing Surgery for Fractured Neck Of Femur Study", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5a087d25d2a641c2f6d6309f23f757ff06746676ac6d0466ba73466c2b56825e", "source_url": "https://clinicaltrials.gov/study/NCT03407573", "start_date": "2017-10-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Hip Fracture Exparel Administration Trial Capsule During Hemiarthroplasty", "completion_date": "2023-08-31", "conditions": [ "Intracapsular Fracture of Femur", "Femoral Neck Fractures", "Hip Hemiarthroplasty" ], "countries": [ "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 455, "evidence_id": "fdf382e40418bdd6", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "Under sixty-five years of age, extracapsular hip fracture, suffer from any form of cognitive compromise that leaves them unable to consent, or if they are treated with any surgical modality other than hip hemiarthroplasty.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 233 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\nMen and women sixty-five years of age and older with isolated intracapsular hip fractures undergoing hemi arthroplasty through a posterior approach with the ability to consent to the study.\n\nExclusion Criteria:\n\nUnder sixty-five years of age, extracapsular hip fracture, suffer from any form of cognitive compromise that leaves them unable to consent, or if they are treated with any surgical modality other than hip hemiarthroplasty.", "eligibility_sha256": "9889a432c27613df4d7f1877fbe2a277287c190258b37fac940b66402c072fc4", "enrollment": 50, "enrollment_type": "ACTUAL", "has_results": true, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Bupivacaine liposome", "Saline" ], "last_update_posted": "2023-11-18", "lead_sponsor": "Maimonides Medical Center", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT03502018", "official_title": "Evaluation of the Efficacy of Exparel Delivered Into the Hip Capsule During Hemiarthroplasty", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4d755e8cbc6949783d345daeb901994fb7da3fd2b5bdeafa0129354c00f5931f", "source_url": "https://clinicaltrials.gov/study/NCT03502018", "start_date": "2018-03-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Quantitative Analysis of Global Proteome in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture", "completion_date": "2019-05-01", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "China" ], "curation_reason": "Proteomic bone-specimen study; arthroplasty is specimen acquisition rather than the randomized strategy.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "1e61f4f54b6187a9", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Ages Eligible for Study: 55-90 Years\n2. Genders Eligible for Study: Woman\n3. Accepts Healthy Volunteers: NO\n4. Study Population: Female patients with hip fracture.\n\nExclusion Criteria:\n\n1. Malignancy or benign ovarian cysts\n2. Known chronic or systemic diseases\n3. Hormone therapy in the previous 3 months\n4. Bone metabolism and drug therapy", "eligibility_sha256": "d31540945b0579ebc82f702ed558941e9167819b1832aaaa7a61f1ed7b786060", "enrollment": 100, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "total hip arthroplasty" ], "last_update_posted": "2018-02-12", "lead_sponsor": "Second Affiliated Hospital of Soochow University", "masking": null, "maximum_age": "90 Years", "minimum_age": "55 Years", "nct_id": "NCT03428672", "official_title": "Collection of Bone Specimens for Quantitative Analysis of Global Proteome and Iron Content Detection", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "FEMALE", "source_sha256": "d576c2ed7a134d7961fcac874adf7bf658dd5a2000ed1a348ed1faf6f4b36508", "source_url": "https://clinicaltrials.gov/study/NCT03428672", "start_date": "2018-04-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA", "completion_date": "2025-12-31", "conditions": [ "Femur Neck Fracture", "Arthroplasty Complications" ], "countries": [ "South Korea" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "mentioned", "end": 367, "evidence_id": "0e5b72e7624e20c6", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "4. Including patients with neuromuscular disorder and cognitive impairment", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 293 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "mentioned" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 226, "evidence_id": "4ebf4eb7aa17f123", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "2. Comorbidities: American Society of Anesthesiology (ASA) grade III or less, Charlson comorbidity 6 points or less", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 111 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Over 60 years of age. Femoral neck fracture or hip joint disease. Garden stage III, IV\n2. Comorbidities: American Society of Anesthesiology (ASA) grade III or less, Charlson comorbidity 6 points or less\n3. Daily activity: UCLA score 4 or higher, Koval score 4 or lower\n4. Including patients with neuromuscular disorder and cognitive impairment\n\nExclusion Criteria:\n\n1. Revision arthroplasty\n2. In case of factors other than fretting corrosion of the index arthroplasty that can cause an increase in serum metal ion level - In case of undergoing surgery using metal on other joints before this operation, vitamin B user\n3. Patients with abnormal kidney function in which Blood urea nitrogen (BUN) and Cr are out of normal values\n4. Pathologic fracture\n5. If you have metabolic bone disorder, exclude osteoporosis (ex. Paraneoplastic syndrome, renal osteodystrophy, Vit D disorder, hormonal disorder)", "eligibility_sha256": "5aeffd1e5439b3df43e283da6e6eed186f4a8b1707192ce2a74b8ff57d19d11a", "enrollment": 54, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Total hip replacement arthroplasty using modular dual mobility cup", "Total hip replacement arthroplasty using conventional acetabular cup" ], "last_update_posted": "2022-01-06", "lead_sponsor": "Korea University Guro Hospital", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT05181566", "official_title": "Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility (MDM) Cup Compared to Conventional Total Hip Arthroplasty (THA) - A Multicenter Prospective Randomized Controlled Study", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ffc470eec4d8522b39a1821a0252e41fd0240dbfc1b25962ec3426c3ad88976e", "source_url": "https://clinicaltrials.gov/study/NCT05181566", "start_date": "2019-09-05", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Probiotics Attenuate Postoperative Cognition Decline", "completion_date": "2023-12-31", "conditions": [ "Necrosis of Femoral Head", "Knee Osteoarthritis", "Fracture of Neck of Femur", "Lumbar Disc Herniation" ], "countries": [ "China" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 408, "evidence_id": "942f7ab8460734b0", "matched_rule": "\\bMMSE\\b", "quote": "2. .MMSE check of less than 24 points.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 370 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 285, "evidence_id": "a84cd23b950a5920", "matched_rule": "\\binformed consent\\b", "quote": "5. . Patient or family informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 246 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 245, "evidence_id": "ca2b8b95e6e9da5d", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "4. . ASA graded at I-II level", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 216 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "2def5cba1234d927", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. . Age is greater than or equal to 65 years old\n2. . Can communicate normally\n3. . Selective knee ankle, hip replacement or lumbar open reduction and internal fixation under general anesthesia\n4. . ASA graded at I-II level\n5. . Patient or family informed consent\n\nExclusion Criteria:\n\n1. . Have a brain disease, or have a history of brain disease\n2. .MMSE check of less than 24 points.\n3. . History of neurological and psychological disorders including AD, stroke, psychosis\n4. . Serious hearing or visual impairment\n5. . Preoperative systolic blood pressure \\>190mmhg, or diastolic blood pressure \\>100mmhg\n6. . The patient or family refuses", "eligibility_sha256": "4ad4707f475d5d0a8d581614df163121bcd8bcf2fce37a94647793d5ecdec758", "enrollment": 220, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Bifidobacterium triple live capsule", "Placebos" ], "last_update_posted": "2022-05-02", "lead_sponsor": "RenJi Hospital", "masking": null, "maximum_age": "80 Years", "minimum_age": "65 Years", "nct_id": "NCT04017403", "official_title": "Probiotics Oral Administration Attenuate Postoperative Cognition Decline in Elderly Orthopedic Patients", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5c34e459e6f1e21f4571df5fd3c8fc9b75569168f06dbedac9fb39d4c94076c8", "source_url": "https://clinicaltrials.gov/study/NCT04017403", "start_date": "2019-12-15", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Nurse Led Ultrasound Guided Femoral Nerve Block in the Emergency Department", "completion_date": "2022-12-31", "conditions": [ "Hip Fractures", "Anesthesia", "Femoral Neck Fractures" ], "countries": [ "Norway" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 266, "evidence_id": "f81620d683cedffd", "matched_rule": "\\bdementia\\b", "quote": "* Patients with dementia", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 242 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 219, "evidence_id": "39e56053668b7bbe", "matched_rule": "\\binformed consent\\b", "quote": "* Written informed consent by patient", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 182 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 181, "evidence_id": "9a07fcaf960b658a", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* American Society of Anesthesiologists classification (ASA) 1-4", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 117 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "caf691b209a860e3", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 110 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients arriving at the emergency department diagnosed with a hip fracture (X-ray confirmed)\n* American Society of Anesthesiologists classification (ASA) 1-4\n* Written informed consent by patient\n\nExclusion Criteria:\n\n* Patients with dementia\n* Known allergies to local anesthetic used in femoral nerve block.\n* The patient is anticoagulated or uses platelet inhibitors. Acetylsalicylic acid and dipyridamole is allowed. If a recent (last 2 hours) International normalized ratio (INR) is below \\<1.5 the patient can be included.\n* Pregnant\n* Age \\<18 years\n* Severe head injury which leads to significant loss of consciousness (Glascow coma score (GCS) \\<12)\n* \\>10 mg or more morphine administrated pre-hospital\n* Skin lesions/infection at block site\n* Patients admitted with other suspected or verified fractures, except small fractures in hands and foots.", "eligibility_sha256": "5e4982e27ca0c2faedb044954c5a086a012b8f4fb4b567c908f7114a7c07ec19", "enrollment": 42, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Nurse-led femoral nerve block" ], "last_update_posted": "2023-10-30", "lead_sponsor": "Espen Lindholm", "masking": null, "maximum_age": "110 Years", "minimum_age": "18 Years", "nct_id": "NCT04145752", "official_title": "Acute Pain in Hip Fracture Patients: Pain Management in the Emergency Department, a Mixed Method Study\u00a8. Nurse Led Ultrasound Guided Femoral Nerve Block in the Emergency Department", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "c5b94953e723f9e536fba3668abe5cc511fb7fce0365dec8658d9648f8403dd8", "source_url": "https://clinicaltrials.gov/study/NCT04145752", "start_date": "2020-02-11", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Efficacy of Intraoperative Periarticular Injections in Hip Fracture Hemiarthroplasty", "completion_date": "2022-02-13", "conditions": [ "Femoral Neck Fractures", "Hemiarthroplasty", "Blood Loss Requiring Transfusion" ], "countries": [ "Turkey (T\u00fcrkiye)" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "effa4d47e8a4f84a", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 95 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Clinical diagnosis of femoral neck fracture\n\nExclusion Criteria:\n\n* Anti-aggregant, anti-coagulant or anti-thrombotic therapy\n* Pathological fractures, periprosthetic fractures, or revision procedures\n* Intolerance or allergy to the medications utilized in the study\n* Refused to participation", "eligibility_sha256": "2485a236ae9343189c967dde28ec5b9b466146d9e02fe2f50013610eb9334155", "enrollment": 84, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Periarticular Injection (PAI)", "Control (Standard treatment)" ], "last_update_posted": "2024-11-25", "lead_sponsor": "Ankara City Hospital Bilkent", "masking": null, "maximum_age": "95 Years", "minimum_age": "58 Years", "nct_id": "NCT06701695", "official_title": "Efficacy of Intraoperative Periarticular Injections in Reducing Blood Loss and Transfusion Requirements in Hip Fracture Hemiarthroplasty: A Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "9a177e35406ef952b4980e62a0e1d495771d63030da0d0adc8f3f92f2872a092", "source_url": "https://clinicaltrials.gov/study/NCT06701695", "start_date": "2020-05-11", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Mini-invasive Preventive Fixation of the Contralateral Femoral Neck in Patients Operated on for a Femoral Neck Fracture", "completion_date": "2025-09-01", "conditions": [ "Femoral Neck Fractures" ], "countries": [], "curation_reason": "Contralateral preventive fixation rather than treatment of the index fracture.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 1516, "evidence_id": "ead880e7773fed8d", "matched_rule": "\\blegal representative\\b", "quote": "* patients with a legal representative (tutorship or guardianship) and insane patients will be excluded", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1413 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 1412, "evidence_id": "3c32b9ee0121b0be", "matched_rule": "\\blife expectancy\\b", "quote": "* patients with an life expectancy of less than 3 months", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1356 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 813, "evidence_id": "04ac30badbd4f458", "matched_rule": "\\bambul(?:ant|atory|ate|ation)\\b", "quote": "* non ambulatory patients", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 788 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* women and men\n* 80 years or older\n* operated on for a femoral neck fracture\n* presenting one, or more, added clinical risk factor of hip fracture\\*\n* a fragility fracture in the past five years\n* a history of fall in the past 12 months (not considering the fall that led to the present fracture)\n* a very high risk of falling: use of psychoactive medication or impaired vision or impaired neuromuscular function\n* BMI lower than 20kg/m2\n* giving her/his consent.\n* affiliated to the social security\n\nExclusion Criteria:\n\n* history of a contralateral proximal femoral fracture\n* history of a surgical operation of the contralateral proximal femur\n* ongoing infection (bone or soft-tissue) on the contralateral hip\n* contraindication of MIPF of the contralateral hip\n* non ambulatory patients\n* patients already included in the study\n* patients with contraindication to the medical devices under evaluation\n* patients not suitable for a surgical procedure (including not suitable for an anaesthetic)\n* patients with a benign or malignant bone lesion of the contralateral femur\n* patients included in another clinical research which could directly have an effect on the femoral neck bone strength\n* patients presenting with a grade 4 Kellgren-Lawrence osteoarthritis of the contralateral hip and reporting significant clinical symptoms\n* patients with an life expectancy of less than 3 months\n* patients with a legal representative (tutorship or guardianship) and insane patients will be excluded", "eligibility_sha256": "0112219b1bf0df6ce0f6796f89869913f048be64bf4ea1f774da2c6059de9b0a", "enrollment": 812, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Preventive fixation of the contralateral femoral neck (Stryker Trauma and Depuy Synthes screws)" ], "last_update_posted": "2020-05-29", "lead_sponsor": "Assistance Publique - H\u00f4pitaux de Paris", "masking": null, "maximum_age": null, "minimum_age": "80 Years", "nct_id": "NCT04408053", "official_title": "Mini-invasive Preventive Fixation of the Contralateral Femoral Neck in Patients Operated on for a Femoral Neck Fracture", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "0ca6e3ca8f6eb3878555a57e7726394163b665799f750dabe88fd845646095eb", "source_url": "https://clinicaltrials.gov/study/NCT04408053", "start_date": "2020-09-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Influence of the Spatial Distribution of Hollow Screws on the Blood Supply and Prognosis of Femoral Neck Fractures", "completion_date": "2023-08-31", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "China" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 318, "evidence_id": "742e49fa85415432", "matched_rule": "\\binformed consent\\b", "quote": "* Able to fully understand and voluntarily sign informed consent.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 253 }, { "effect": "restrictive", "end": 691, "evidence_id": "51379e6630e05629", "matched_rule": "\\binformed consent\\b", "quote": "* Those who refuse to sign informed consent;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 647 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 217, "evidence_id": "655bf4b53c3db783", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA score 1-2, can tolerate anesthesia;", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 176 }, { "effect": "restrictive", "end": 601, "evidence_id": "3df2e64e4f87db0f", "matched_rule": "\\b(?:able to |can |cannot )?tolerate (?:surgery|the operation)\\b", "quote": "* Those who have general conditions or accompanying diseases that make it difficult for people to tolerate surgery, such as: coagulation dysfunction, or heart, liver, and kidney dysfunction;", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 411 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "8dd0aa3b740e3a7a", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* A new initial intracapsular fracture of the femoral neck;\n* Garden classification I or II;\n* Accept closed reduction robot-assisted hollow nail surgery;\n* ASA score 1-2, can tolerate anesthesia;\n* Age 60-80 years old (inclusive);\n* Able to fully understand and voluntarily sign informed consent.\n\nExclusion Criteria:\n\n* Old or pathological fractures;\n* Patients with acetabular fracture;\n* Those who have general conditions or accompanying diseases that make it difficult for people to tolerate surgery, such as: coagulation dysfunction, or heart, liver, and kidney dysfunction;\n* Severe infections systemically or locally;\n* Those who refuse to sign informed consent;\n* In any case, if the researcher believes that the patient is not suitable for this treatment or there are other factors that affect the efficacy of the observation of this study.", "eligibility_sha256": "39dafd9fbfbb9acc633e93009422b587734e79c329f4d9a4cbefab876c7edae3", "enrollment": 68, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Triangular Nail Placement of Femoral Neck" ], "last_update_posted": "2021-12-28", "lead_sponsor": "RenJi Hospital", "masking": null, "maximum_age": "80 Years", "minimum_age": "60 Years", "nct_id": "NCT05171140", "official_title": "Influence of Different Spatial Distribution of Hollow Screws on Blood Supply and Prognosis of Femoral Neck Fractures in the Elderly", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ec302e7f6918507f7914d31a38b1a5412a5e80a1403f33939f0c0b7a35dfc17c", "source_url": "https://clinicaltrials.gov/study/NCT05171140", "start_date": "2020-09-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Which Analgesia is Better for Proximal Femoral Fractures?", "completion_date": "2022-03", "conditions": [ "Proximal Femur Fracture" ], "countries": [ "Egypt" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 97, "evidence_id": "42f8f9506819d250", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* American Society of Anesthesiologists (ASA) physical status I, II and III.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "58b60c33febaca01", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) physical status I, II and III.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Neuromuscular diseases\n* Hematological diseases\n* Bleeding abnormality\n* Coagulation abnormality.\n* Psychiatric diseases.\n* Local skin infection at the site of the block.\n* Local skin sepsis at the site of the block\n* Known intolerance to the study drugs.\n* Body Mass Index \\> 40 Kg/m2.\n* Multiple trauma patients.", "eligibility_sha256": "376d8e9ef5fb84e9150078678dd4fc73966906a36f50e3c7b3d5b76e38ce4381", "enrollment": 100, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Fascia iliaca block", "combined LFCN block with PENG block" ], "last_update_posted": "2020-09-23", "lead_sponsor": "Mansoura University", "masking": null, "maximum_age": "90 Years", "minimum_age": "50 Years", "nct_id": "NCT04309539", "official_title": "- Efficacy of Combined Lateral Femoral Cutaneous Nerve Block With Pericapsular Nerve Group Block Versus Fascia Iliaca Block in Proximal Femoral Fractures", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "7e59a8f80e83ff3fda830a3f81d481fa31aa2b55c39d1edea570be2731dbc358", "source_url": "https://clinicaltrials.gov/study/NCT04309539", "start_date": "2020-09-21", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "PENG Versus Femoral Nerve Block in Neck of Femur Fracture", "completion_date": "2021-12-01", "conditions": [ "Neck of Femur Fracture" ], "countries": [ "Ireland" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 285, "evidence_id": "ce6e3f7863c40bc6", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Patient refusal Coagulopathy Local infection Allergy to Local Anaesthetics Significant cognitive impairment (4AT score\\>=4) Weight \\<60kg", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 146 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 123, "evidence_id": "2e674c32be8fe109", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* All patients scheduled for operative repair of hip fracture Patient age 16 years or more ASA I - III", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* All patients scheduled for operative repair of hip fracture Patient age 16 years or more ASA I - III\n\nExclusion Criteria:\n\n* Patient refusal Coagulopathy Local infection Allergy to Local Anaesthetics Significant cognitive impairment (4AT score\\>=4) Weight \\<60kg", "eligibility_sha256": "656fe185bb17edeadc8aa663f17d2950fa7dc01d1adde536fa8b4c9d8dd72d13", "enrollment": 64, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Lidocain" ], "last_update_posted": "2021-08-12", "lead_sponsor": "University College Cork", "masking": null, "maximum_age": null, "minimum_age": "16 Years", "nct_id": "NCT05002725", "official_title": "A Comparison of Quadriceps Muscle Weakness Associated With PENG Blockade or Femoral Nerve Blockade for Patients Undergoing Neck of Femur (NOF) Fracture Surgery", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "764f1e561244b4898a0c00acd494c2ce6a28418292748d7b55922d175cb6708b", "source_url": "https://clinicaltrials.gov/study/NCT05002725", "start_date": "2021-01-28", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Functional Outcome After ORIF or Arthroplasty for Femoral Neck Fracture", "completion_date": "2027-09-01", "conditions": [ "Hip Fractures", "Femoral Neck Fractures", "Undisplaced Fracture", "Treatment Complication", "Internal Fixation; Complications", "Arthroplasty Complications" ], "countries": [ "Sweden" ], "curation_reason": "HipSTHeR substudy sharing sponsor and population with primary record NCT03966716.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 134, "evidence_id": "8193c77009713050", "matched_rule": "\\binformed consent\\b", "quote": "* Informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 116 }, { "effect": "restrictive", "end": 249, "evidence_id": "f41d4759d9ea936d", "matched_rule": "\\binformed consent\\b", "quote": "* No informed consent", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 228 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Undisplaced (Garden I-II) femoral neck fracture (within 72h)\n* Treated at participating unit\n* Informed consent\n* Amenable for both treatment options\n* Included in the Hipsther trial\n\nExclusion Criteria:\n\n* No informed consent\n* Pathological or stress fracture\n* Peri-implant fracture\n* Previous inclusion of a contralateral Garden 1 or 2 femoral neck fracture", "eligibility_sha256": "6db57bc4c13cd1f5f23e8a2781854fb907312f3c2178f3523db52fd3e7a561aa", "enrollment": 340, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Treatment" ], "last_update_posted": "2024-12-03", "lead_sponsor": "Uppsala University", "masking": null, "maximum_age": null, "minimum_age": "75 Years", "nct_id": "NCT06152198", "official_title": "Internal Fixation Versus Hip Replacement in Older Adults with an Garden I/II Femoral Neck Fracture: Physical Function and Pain in Elderly Patients - a Substudy of the Hipsther Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "linked_secondary", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "bcbd53db24f3e4ed81af135e9fedc4b3647e547875de4f6e6c6cf083b14c86be", "source_url": "https://clinicaltrials.gov/study/NCT06152198", "start_date": "2021-06-20", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "the Effects of Perioperative Goal Directed and Conventional Fluid Management on the IVC Collapsibility Index", "completion_date": "2021-10-15", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Turkey (T\u00fcrkiye)" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 67, "evidence_id": "2005779ef9c561e4", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* 1-3 ASA anesthesia risk", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 42 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "98c630e8db05dc81", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 101 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* 65 years and older\n* 1-3 ASA anesthesia risk\n* Planned to undergo proximal femoral surgery due to intertochanteric fracture\n\nExclusion Criteria:\n\n* cardiac arrhythmia,\n* chronic renal failure and those on dialysis,\n* heart failure,\n* aortic insufficiency,\n* active lower/upper respiratory tract infections,\n* inferior vena cava cannot be clearly visualized by USG, BMI\\>35, Patients in need of postoperative intensive care or ASA4, Patients with advanced obstructive or restrictive respiratory diseases, Patients under 65 years of age.", "eligibility_sha256": "11a50cefd485d085883ba4f6aa34cf7440c60204ef66d42325da8457b1b5a8e7", "enrollment": 60, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "mostcare hemodynamic monitor" ], "last_update_posted": "2021-12-13", "lead_sponsor": "Fatih Sultan Mehmet Training and Research Hospital", "masking": null, "maximum_age": "101 Years", "minimum_age": "65 Years", "nct_id": "NCT05154435", "official_title": "Comparison of the Effects of Perioperative Targeted and Traditional Fluid Management on Inferior Vena Cava Collapsibility Index and Postoperative Complications in Geriatric Patients Undergoing Proximal Femoral Surgery", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "c4d5f1474fb0ee257792e324b84d2f56e907630c010241aa0d233bf7a253e62e", "source_url": "https://clinicaltrials.gov/study/NCT05154435", "start_date": "2021-07-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Early Functional Outcomes in Unisplaced Neck of Femur Fracture Treated With Partially Threaded and Fully Threaded Cannulated Screw Fixation in Patients of Age 60 and Above", "completion_date": "2022-07-30", "conditions": [ "Neck of Femur Fracture" ], "countries": [ "Pakistan" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients of garden type I or II fractures.\n* All patients to be mobile before femoral neck fracture.\n\nExclusion Criteria:\n\n* Patients having open fracture.\n* Patients with present or past history of chronic kidney disorder.\n* Patients presenting with hemorrhage.\n* Patient with nervous stroke\n* Patients unwilling to be part of this study.", "eligibility_sha256": "eed4227bea280c1fb891d294d0682272bf83303518155fcd5672be672370bbc8", "enrollment": 82, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Fully threaded cannulated screws" ], "last_update_posted": "2022-10-20", "lead_sponsor": "Nishtar Medical University", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT05587660", "official_title": "Early Functional Outcomes in Unisplaced Neck of Femur Fracture Treated With Partially Threaded and Fully Threaded Cannulated Screw Fixation in Patients of Age 60 and Above", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "3cf220c9c0a778db7deecc0c81a49a55f7ee4c898ce8093924cb7bfe657d6e0e", "source_url": "https://clinicaltrials.gov/study/NCT05587660", "start_date": "2021-07-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time", "completion_date": "2026-11-01", "conditions": [ "Femoral Neck Fractures" ], "countries": [ "Switzerland" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 1008, "evidence_id": "5bc5b8a4badbebf5", "matched_rule": "\\bdementia\\b", "quote": "* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 867 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 286, "evidence_id": "e542228bfb65277d", "matched_rule": "\\binformed consent\\b", "quote": "* Patients able to provide informed consent and follow all the study procedures as indicated by the protocol", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 178 }, { "effect": "mentioned", "end": 332, "evidence_id": "585f8166d616f6f7", "matched_rule": "\\binformed consent\\b", "quote": "* Informed Consent as documented by signature", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 287 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 613, "evidence_id": "de1a9382a21659f6", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* Presence of other clinically significant concomitant disease states (ASA IV)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 535 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "7d34a53e4903baec", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients undergoing unilateral cemented hip endoprosthesis for femoral neck fracture\n* Patients aged 50-90 years old\n* Patients with a BMI \\>18.5 and \\<35\n* Patients able to provide informed consent and follow all the study procedures as indicated by the protocol\n* Informed Consent as documented by signature\n\nExclusion Criteria:\n\n* Contraindications to steroids\n* Revision endoprosthesis\n* Active steroid or immunosuppressive therapy in the last 30 days before the operation\n* Pregnant or breast-feeding women\n* Presence of other clinically significant concomitant disease states (ASA IV)\n* Uncontrolled diabetes mellitus\n* Contraindications to NSAIDs\n* Chronic systemic diseases as immunodeficiency, autoimmune disease (Systemic Lupus Erythematosus, SLE), gout, rheumatic arthritis\n* Known or suspected non-compliance, drug or alcohol abuse\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant.\n* Participation in another study with investigational drug within the 30 days preceding and during the present study\n* Previous enrolment into the current study\n* Enrolment of the investigator, his/her family members, employees and other dependent persons.", "eligibility_sha256": "c07b5c86934bbda1f85ed73ab07014887b6fe7ae9f272ff96e45e398adc8f167", "enrollment": 110, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)" ], "last_update_posted": "2026-03-05", "lead_sponsor": "Ente Ospedaliero Cantonale, Bellinzona", "masking": null, "maximum_age": "90 Years", "minimum_age": "50 Years", "nct_id": "NCT05023369", "official_title": "Periarticular Administration of Dexamethasone to Improve Post-operative Pain, Function, Nausea, Hospitalization Length, and Risk of Complications in Patients Undergoing Hip Arthroplasty - A Randomized Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "2198078ba53ad89544b9d60bb1134ff6d99ec8b957cf4f750ec9a6b64fe23b64", "source_url": "https://clinicaltrials.gov/study/NCT05023369", "start_date": "2021-12-10", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture", "completion_date": "2027-01-31", "conditions": [ "Femoral Neck Fractures", "Prosthetic Infection" ], "countries": [ "Sweden" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age \u226560 years\n* Diagnosis: displaced femoral neck fracture type AO 31-B2 or B3/Garden type 3 or 4\n* Eligible for HA according to local guidelines and routines\n\nExclusion Criteria:\n\n* Previous inclusion of contralateral hip in the present study\n* Pathological or stress fracture of the femoral neck, or fracture adjacent to a previous ipsilateral hip implant\n* Unavailability of both interventions for a study participant (e.g., sensitivity to any of the components in the bone cement)\n* Patients that have actively marked their hospital charts with an added privacy notice", "eligibility_sha256": "ac9eaa3bb824d68bfbfa3b37cd5f42d8a30d3a3f815061a292f3ef0db6c6472e", "enrollment": 7000, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "COMBINATION_PRODUCT" ], "interventions": [ "antibiotic loaded bone cement (gentamicin+clindamycin) COPAL G+C (Heraeus).", "antibiotic loaded bone cement (gentamicin) Paladins R+G (Heraeus) or Refobacin (Biomet)." ], "last_update_posted": "2026-03-10", "lead_sponsor": "Ume\u00e5 University", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT05164081", "official_title": "DAICY Trial - Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture: A Register-based Cluster-randomized Cross-over Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ce918316addae2acc4d2600f02b6f4b70310d21d81e4ed36786fc2fcec6e18cb", "source_url": "https://clinicaltrials.gov/study/NCT05164081", "start_date": "2022-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Study to Evaluate the Safety and Efficacy of OR3O\u2122 Dual Mobility System vs. Conventional Single Bearing Design Total Hip System", "completion_date": "2023-11-03", "conditions": [ "Degenerative Hip Joint Disease", "Rheumatoid Arthritis (RA)", "Femoral Neck Fractures", "Avascular Necrosis of Femoral Head", "Osteoarthritis (OA)", "Hip Dislocation", "Hip Fractures" ], "countries": [ "China" ], "curation_reason": "General primary-total-hip device trial with mixed indications and no fracture-specific randomized cohort.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 1032, "evidence_id": "578112c6d27ed5a5", "matched_rule": "\\binformed consent\\b", "quote": "* Subject provides written informed consent for study participation using an Ethical Committee (EC) approved consent form before any study procedures are performed, including pre-operative data review and/or collection of data on electronic Case Report Forms (eCRFs).", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 765 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [ { "effect": "restrictive", "end": 1988, "evidence_id": "90cd7ebb74e168df", "matched_rule": "\\blife expectancy\\b", "quote": "* Subject has life expectancy of less than 2 years.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 1937 } ], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "restrictive" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 2476, "evidence_id": "0ea202f43ffc9c2c", "matched_rule": "\\bgait\\b", "quote": "* Subject has neuromuscular dysfunctions (paralysis, myolysis and abductor muscle weakness) which will cause unstable hip joint or abnormal gait after surgery.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 2317 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "41b38d17b3274d04", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Subject is a suitable candidate for implanting the OR3O\u2122 Dual Mobility System or single-bearing design Total Hip System in primary total hip replacement in the Investigator's judgement.\n* Subject is skeletally mature in the Investigator's judgement.\n* Subject is 18 - 80 years old (inclusive).\n* Subject is receiving total hip replacement for the first time on the affected hip.\n* Subject has any of the following conditions:\n\n * Advanced degeneration of the hip joint as a result of degenerative, post-traumatic, or rheumatoid arthritis(RA);\n * Fracture or avascular necrosis of the femoral head;\n * All forms of osteoarthritis(OA);\n * Patients with hips at risk of dislocation;\n * Femoral neck fracture or proximal hip joint fracture.\n* Subject provides written informed consent for study participation using an Ethical Committee (EC) approved consent form before any study procedures are performed, including pre-operative data review and/or collection of data on electronic Case Report Forms (eCRFs).\n* Subject is willing and able to participate in required follow-up visits and is able to complete study activities.\n* Subjects with preoperative HHS \u2264 79 (fair or worse category).\n\nExclusion Criteria:\n\n* Subject has conditions that would eliminate or tend to eliminate adequate implant support or prevent the use of an appropriately-sized implant, e.g.:\n\n * blood supply limitations;\n * insufficient quantity or quality of bone support, e.g., osteoporosis, metabolic disorders which may impair bone formation, radioactive bone disease, tumor around hip joint, and osteomalacia;\n * infections or other conditions which may lead to increased bone resorption.\n* Subject has dysplasia of hip joint with CROWE Grade III, IV.\n* Subject has weak constitution or failing to endure the surgery due to other diseases of the body.\n* Subject has bodily disease(s) that may interfere with THA survival or outcome.\n* Subject has life expectancy of less than 2 years.\n* Subject has mental or neurological conditions which impair the subject's ability or willingness to restrict activities that may put the affected limb at risk.\n* Subject has physical conditions or activities which tend to place extreme loads on implants, e.g., Charcot joints, muscle deficiencies, multiple joint disabilities.\n* Subject has neuromuscular dysfunctions (paralysis, myolysis and abductor muscle weakness) which will cause unstable hip joint or abnormal gait after surgery.\n* Subject has a mental or neurological condition that would pre-empt their ability or willingness to participate in the study including mental illness, mental retardation, drug or alcohol abuse.\n* Subject has an active infection - systemic or at the site of intended surgery.\n* Subject has a Body Mass Index \u2265 40.0 kg/m\u00b2.\n* Subject has a known allergy to any component of the devices used in the study.\n* Subject is pregnant or breast feeding.\n* Subject is entered in another investigational drug, biologic, or device study within 30 days of active study participation.\n* Subjects that are expected with poor compliance.\n* Subjects with complications of other diseases are limited to participate in the research, not able to comply with the follow-up or have impact on scientific integrity.\n* Subjects with preoperative HHS \u2265 80 (good to excellent category).\n* Subject has other diseases or conditions that investigator considers not appropriate to participate in the study.", "eligibility_sha256": "660a20c3ae78db4a8a177582fff8007ddff167e179704ad065c44d74a3adf5e2", "enrollment": 24, "enrollment_type": "ACTUAL", "has_results": true, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "OR3O\u2122 - Dual Mobility System", "Conventional" ], "last_update_posted": "2025-05-21", "lead_sponsor": "Smith & Nephew Medical (Shanghai) Ltd", "masking": null, "maximum_age": "80 Years", "minimum_age": "18 Years", "nct_id": "NCT04941729", "official_title": "A Prospective, Multi-center, Randomized, Controlled Study to Evaluate the Safety and Efficacy of the OR3O\u2122 Dual Mobility System Versus Conventional Single Bearing Design Total Hip System in Primary Total Hip Arthroplasty (THA) Procedures.", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "TERMINATED", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "e644c3049d16fa8af654064e0fee384ad2bff5d30f3efdbb84cb72d0e4b157fc", "source_url": "https://clinicaltrials.gov/study/NCT04941729", "start_date": "2022-06-24", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery", "completion_date": "2022-09-01", "conditions": [ "Hip Surgery", "Femoral Neck Fractures" ], "countries": [ "Turkey (T\u00fcrkiye)" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 117, "evidence_id": "62b3df24b255ac55", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* American Society of Anesthesiologists (ASA) physical status I, II, or III", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 42 }, { "effect": "restrictive", "end": 466, "evidence_id": "6a42459894534cfe", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* American Society of Anesthesiologists (ASA) physical status IV or higher", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 392 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "6cfec2b6fbc59ab6", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age 18 to 80 years\n* American Society of Anesthesiologists (ASA) physical status I, II, or III\n* Patients diagnosed with hip fracture requiring surgical intervention\n* Patients diagnosed with proximal femur fracture requiring surgical intervention\n\nExclusion Criteria:\n\n* Known allergy to local anesthetic agents\n* Patients younger than 18 years or older than 80 years\n* American Society of Anesthesiologists (ASA) physical status IV or higher\n* Lumbar skeletal deformity or history of previous lumbar spine surgery\n* Contraindications to regional anesthesia (e.g., coagulopathy, infection at the injection site, severe hypovolemia, patient refusal)\n* Pregnancy", "eligibility_sha256": "b43be7e68b313f500f8d4b2c451d645ed498e615f5a649a79c8cc99bc7c6aa78", "enrollment": 66, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Ultrasound-Guided Lumbar Erector Spinae Plane Block (L4)", "Spinal Anesthesia (L4-L5)" ], "last_update_posted": "2026-04-15", "lead_sponsor": "Gaziantep City Hospital", "masking": null, "maximum_age": "80 Years", "minimum_age": "18 Years", "nct_id": "NCT07427082", "official_title": "Comparison of Efficacy and Safety Between Ultrasound-Guided L4 Level Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "82483ccba3046e2692e3868c9379d6e0bee9f6393c6cc61eba294945cdf4e89e", "source_url": "https://clinicaltrials.gov/study/NCT07427082", "start_date": "2022-07-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "PENG vs FICB for Hip Fracture in ED Patients", "completion_date": "2026-06-01", "conditions": [ "Femoral Neck Fractures", "Intertrochanteric Fractures" ], "countries": [ "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Proximal femur fracture\n\nExclusion Criteria:\n\n* refusal to consent\n* hemodynamic instability\n* allergy to local anesthetics\n* severe injury with instability\n* severe medical conditions with instability", "eligibility_sha256": "c583c1c06a4a108e45db0097fc4f783e1277d84c21064ff1581d991caed98f90", "enrollment": 50, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "PENG", "FICB" ], "last_update_posted": "2026-06-03", "lead_sponsor": "University of Virginia", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT05505604", "official_title": "Comparison of Pericapsular Nerve Group Block (PENG) Versus Fascia Iliaca Compartment Block (FICB) for Hip Fracture Analgesia in Emergency Department Patients", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "e906f905171cda16e039189cbddd136e30b7acf86b626173c126ae2e89a25d55", "source_url": "https://clinicaltrials.gov/study/NCT05505604", "start_date": "2022-09-30", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial", "completion_date": "2023-12-31", "conditions": [ "Post Operative Pain" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 139, "evidence_id": "67923cd3e5c254f3", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA status I-III", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 121 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "b6e0602cb405211f", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 80 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age group (18-80)\n* Undergoing elective/emergency femur fracture repair under sub-arachnoid block\n* ASA status I-III\n\nExclusion Criteria:\n\n* Participation in any other trial\n* Known hypersensitivity to study medications\n* Seizure disorder\n* Coagulation disorder\n* Infection over injection site\n* Hemodynamic Instability\n* Concurrent medications use that is contraindicated with study medications", "eligibility_sha256": "4e0f545794cdbb5c788ec2247065ff6f61c4b769477bdfa643ac4dce198f594d", "enrollment": 60, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Dexamethasone", "Dexmedetomidine" ], "last_update_posted": "2022-08-02", "lead_sponsor": "Aga Khan University Hospital, Pakistan", "masking": null, "maximum_age": "80 Years", "minimum_age": "18 Years", "nct_id": "NCT05484648", "official_title": "Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "0452b3a79535df9dbf891587c3326af4367ef8936ed68ca650800c19c5a306ea", "source_url": "https://clinicaltrials.gov/study/NCT05484648", "start_date": "2023-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Regional Anesthesia by PENG-Block in Emergency Department", "completion_date": "2023-12-25", "conditions": [ "Hip Fractures" ], "countries": [ "France" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n1. Adult patients (\u226518 years old) admitted to the emergency department for a hip fracture\n2. Pain assessed by VAS/NRS \u2265 3 when the clinical suspicion of hip fracture is confirmed by the emergency physician\n3. Patients capable of expressing his/her consent prior to participation in the study\n4. Affiliated to or beneficiary of a social security regimen\n\nExclusion Criteria:\n\n1. Patients for who it is impossible to collect the pain assessment scale\n2. Patients with known or suspected bleeding disorders :\n\n * Personal and family history of bleeding symptoms (spontaneous or induced)\n * Clinical signs suggesting a haemostasis disorder\n * Patient on anticoagulant at a curative dose with a very high risk of bleeding (labile International Normalized Ratio (INR), mechanical valve, acute kidney failure and treatment with direct oral anticoagulants)\n * Inherited bleeding disorder (Hemophilia A, Hemophilia B, Von Willebrand disease, Fibrinogen deficiency, Factor XII deficiency)\n * Pathologies that may interfere with hemostasis: advanced liver disease, decompensated hematological disease, collagen diseases such as Ehlers-Danlos disease\n3. Patients in whom it is impossible to perform the PENG-Block: Body Mass Index (BMI) \\> 40, adenopathy or infection at the puncture site, allergy to the anesthetics used\n4. Pregnant, parturient or breastfeeding women\n5. Patients under judicial protection or judicial safeguard\n6. Any other reason which, in the opinion of the investigator, could interfere with the evaluation of the study objectives", "eligibility_sha256": "403c21222d19f7ec065f4a266f9cd7c0dc3f71bb1e14b6d9008b950fb3c591d0", "enrollment": 36, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "COMBINATION_PRODUCT" ], "interventions": [ "PENG Block", "Multimodal analgesia" ], "last_update_posted": "2025-12-05", "lead_sponsor": "Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT05673486", "official_title": "Analgesic Efficacy of Regional Anesthesia by PENG-Block in Patients Diagnosed With Hip Fractures in the Emergency Department: an Open-label Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "7666add763470c89ee9e4fcec3745c440411d6af0653e6147bae3b901281f71c", "source_url": "https://clinicaltrials.gov/study/NCT05673486", "start_date": "2023-03-31", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures", "completion_date": "2025-12-30", "conditions": [ "Proximal Femoral Fractures" ], "countries": [ "Italy" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 401, "evidence_id": "b85842483e5dd712", "matched_rule": "\\binformed consent\\b", "quote": "* Informed Consent: Patients must provide signed informed consent to participate in the study", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 308 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "bbd0c28256716a34", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 100 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients must be older than 65 years\n* Fracture Type: The study includes patients with medial femoral neck fractures classified as AO type B1, B2, and B3, indicating specific types of hip fractures.\n* Surgical Indication: Patients should have an indication for prosthetic hip surgery.\n* Informed Consent: Patients must provide signed informed consent to participate in the study\n\nExclusion Criteria:\n\n* Fracture Type: Exclusion of patients with trochanteric region fractures and femoral head fractures (AO classification types A and C), periprosthetic fractures, patients with multiple traumas or multiple fractures.\n* Blood Test Anomalies: Patients with pre-operative blood test anomalies, such as ionic disorders and hemoglobin levels lower than 8 g/dL.\n* Renal Insufficiency: Patients with renal insufficiency.\n* Active Infections: Exclusion of patients with active infections or suspected/confirmed hypersensitivity or allergy to gentamicin, history of toxicity or reaction to aminoglycosides.", "eligibility_sha256": "15d631c60ed9e6cb8c2ece7e494c15dab388226101fab10832e6331834cb1570", "enrollment": 450, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG", "OTHER" ], "interventions": [ "Antibiotic loaded", "Placebo" ], "last_update_posted": "2024-01-11", "lead_sponsor": "Universit\u00e0 Vita-Salute San Raffaele", "masking": null, "maximum_age": "100 Years", "minimum_age": "65 Years", "nct_id": "NCT06200402", "official_title": "Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures: A Prospective, Randomized, Single-Center, Blinded Study", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ac54d7a2121be0c22a350e4618355367a6df0a6501b945c19472d489ecefd9d4", "source_url": "https://clinicaltrials.gov/study/NCT06200402", "start_date": "2023-07-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Improvement of Function After Hip Fracture in Geriatric Rehabilitation Unit Via Augmented Reality Device \"SELFIT\"", "completion_date": "2024-07", "conditions": [ "Hip Fractures" ], "countries": [ "Israel" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 509, "evidence_id": "6fa54ab4ee5df1a1", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Patients with cognitive decline following dementia or delirium", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 445 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 93, "evidence_id": "8efe388ed9516964", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Ability to walk independently or under supervision before the fracture", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 }, { "effect": "mentioned", "end": 232, "evidence_id": "6d4d6b3083d34500", "matched_rule": "\\bweight[- ]bearing\\b", "quote": "* Patients with full weight bearing on the operated leg according to the instructions of an orthopedic surgeon (FWB - Full Weight Bearing)", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 94 }, { "effect": "restrictive", "end": 343, "evidence_id": "9be6ccde82a2ac69", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Patients who are able to walk with an assistive device FIM 3 and above (FIM Functional independence measure)", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 233 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Ability to walk independently or under supervision before the fracture\n* Patients with full weight bearing on the operated leg according to the instructions of an orthopedic surgeon (FWB - Full Weight Bearing)\n* Patients who are able to walk with an assistive device FIM 3 and above (FIM Functional independence measure)\n* Mental competence after a comprehensive assessment by a Geriatric Specialist\n\nExclusion Criteria:\n\n* Patients with cognitive decline following dementia or delirium\n* Patients with complications after surgery - infection or bleeding in the surgical area\n* Patients with previous neurological injury or current CNS disease.\n* Patients with a previous lower limb fracture in the last 5 years.", "eligibility_sha256": "4f3623206888958ba4fc4e8a6a0ebee82402e1f62e3b010a13a6f72857b7644f", "enrollment": 50, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE", "OTHER" ], "interventions": [ "Selfit Device group", "Control Group" ], "last_update_posted": "2023-09-08", "lead_sponsor": "Meir Medical Center", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT06029361", "official_title": "Improving Function and Mobility in Geriatric Patients After a Femoral Neck Fracture Who Are Undergoing Inpatient Rehabilitation Using an Augmented Reality Practice System - SELFIT", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "7f737839a8b09c3bda036400db5523038cf43ea1807924ed9dabc2f209bd5623", "source_url": "https://clinicaltrials.gov/study/NCT06029361", "start_date": "2023-08-08", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Postoperative Pain Relieve for Patients Undergoing Surgical Treatment of Femoral Fracture", "completion_date": "2025-07-29", "conditions": [ "Proximal Femur Fracture" ], "countries": [ "Czechia" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 46, "evidence_id": "c0380fcc7371649d", "matched_rule": "\\binformed consent\\b", "quote": "* signed informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 192, "evidence_id": "becc611ed79c8275", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* The American Society of Anesthesiologists (ASA) classification I to III", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 119 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "8893a751604c523b", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* signed informed consent\n* 60 to 90 years of age\n* surgical treatment of proximal femur fracture\n* The American Society of Anesthesiologists (ASA) classification I to III\n* spinal anesthesia used for the operation\n\nExclusion Criteria:\n\n* general anesthesia used for the operation\n* allergy to opioids\n* high risk of respiratory depression", "eligibility_sha256": "baea11b399b572af2d81c25920ab35f37c6a5a6e1a9d95a5e2daa026630af1a4", "enrollment": 82, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Intrathecal morphine administration", "Parenteral administration of analgesics" ], "last_update_posted": "2025-11-25", "lead_sponsor": "University Hospital Ostrava", "masking": null, "maximum_age": "90 Years", "minimum_age": "60 Years", "nct_id": "NCT05920642", "official_title": "Risk-benefit Analysis of Intrathecal Morphine Administration to Patients Undergoing Surgical Treatment of Proximal Femoral Fracture (Monocentric, Single-blinded, Randomized Clinical Study Compared to Standard Treatment)", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "126a42797e3672d0dd03fc860dda124e46aee123e999c2d0cb0c43e9943c491c", "source_url": "https://clinicaltrials.gov/study/NCT05920642", "start_date": "2023-09-04", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparison of Unilateral Spinal Anesthesia and Nerve Block in Hip Fractures", "completion_date": "2024-12-15", "conditions": [ "Femur Neck Fracture", "Spinal Anesthesia", "Lumbar Plexus Nerve Block" ], "countries": [ "Turkey (T\u00fcrkiye)" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 222, "evidence_id": "192614d9d1f617af", "matched_rule": "\\binformed consent\\b", "quote": "* Provided informed consent to participate in the study.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 166 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 118, "evidence_id": "f824cf02792038f5", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* American Society of Anesthesiologists (ASA) classification I-IV.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 52 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "a9e28c4b7499ab3b", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age between 18 and 90 years.\n* American Society of Anesthesiologists (ASA) classification I-IV.\n* Scheduled for femoral neck fracture surgery.\n* Provided informed consent to participate in the study.\n\nExclusion Criteria:\n\n* History of allergy to local anesthetics.\n* Presence of coagulopathy or bleeding disorders.\n* Mental health disorders impairing consent or cooperation.\n* Allergy to medications used in the study protocol.\n* Presence of infection at the block site.\n* Body mass index (BMI) \\> 30.\n* Preoperative or intraoperative conversion to general anesthesia.\n* Pregnant patients.\n* Severe spinal deformities preventing regional anesthesia application.\n* Refusal to participate in the study.", "eligibility_sha256": "48b40b7707f74c229c2463169c51c3534295d08805cd03261c3d2e5ddd540215", "enrollment": 50, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Hipobaric Unilateral Spinal Anesthesia Group", "Lumbar Plexus Block (LP-SP)" ], "last_update_posted": "2025-12-09", "lead_sponsor": "Bursa Yuksek Ihtisas Training and Research Hospital", "masking": null, "maximum_age": "90 Years", "minimum_age": "18 Years", "nct_id": "NCT07272226", "official_title": "Comparison of the Effectiveness of Lumbar Plexus Block and Hypobaric Unilateral Spinal Anesthesia in Patients Undergoing Femoral Neck Fracture Surgery", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ba7e6fd21bb32a5dcbcf13f8846a92eebf530738c5a719d3bf4cb7d9b9d5410a", "source_url": "https://clinicaltrials.gov/study/NCT07272226", "start_date": "2023-09-15", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Lumbar Plexus Block Application in Ultrasound-guided Shamrock Method", "completion_date": "2024-02-13", "conditions": [ "Femoral Neck Fractures", "Lumbosacral Plexus", "Nerve Block" ], "countries": [ "Turkey (T\u00fcrkiye)" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 107, "evidence_id": "ca61d467462f8ebb", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA (American Society of Anaesthesiologist) Score I-III risk class", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 39 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "88bee0ca420328e6", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* 18-90 years old\n* ASA (American Society of Anaesthesiologist) Score I-III risk class\n* Patients who will undergo femoral neck fracture operation.\n\nExclusion Criteria:\n\n* Local Anaesthetic Allergy\n* With Bleeding Diathesis Disorder\n* Mental Disorders\n* Allergic to the medicines used\n* Previous Cerebrovascular Disease\n* Body Mass Index above 30", "eligibility_sha256": "e429c0c4134b1890370444feba56477094e69a3413108939ca0c082ce7a44d53", "enrollment": 40, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "in-plane needle guidance", "out-of-plane needle guidance" ], "last_update_posted": "2023-10-18", "lead_sponsor": "Bursa Yuksek Ihtisas Training and Research Hospital", "masking": null, "maximum_age": "90 Years", "minimum_age": "18 Years", "nct_id": "NCT06088368", "official_title": "Investigation of the Efficacy of Different Types of Lumbar Plexus Block Applied With Ultrasound-guided Shamrock Method", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "dd6141098d37b83887654ded3e3b22256b152cb4f13fba28203ab41bf9ed0462", "source_url": "https://clinicaltrials.gov/study/NCT06088368", "start_date": "2023-10-20", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Opioid-Free Pain Treatment in Trauma Patients", "completion_date": "2026-10", "conditions": [ "Femoral Neck Fractures", "Intertrochanteric Fractures", "Femoral Shaft Fracture", "Distal Femur Fracture", "Patella Fracture", "Tibial Shaft Fracture with or Without Associated Fibula Fracture", "Ankle Fracture (bimalleolar Equivalent, Bimalleolar, or Trimalleolar)", "Tibial Pilon Fracture", "Talar Head, Neck, Body, or Process Fractures", "Calcaneus Fractures", "Lisfranc Injuries", "Isolated or Multiple Metatarsal Fractures", "Phalanx Fractures of the Foot, Single or Multiple", "Clavicle Fractures", "Proximal Humerus Fractures", "Humeral Shaft Fractures", "Distal Humerus Fractures (intra or Extra-articular)", "Olecranon Fractures", "Radial Head or Neck Fractures", "Elbow Fractures Involving a Combination of Fractures of the Radius and Uln", "Forearm Fractures (both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft)", "Distal Radius Fractures" ], "countries": [ "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 393, "evidence_id": "b50d228386a8e440", "matched_rule": "\\binformed consent\\b", "quote": "* Patients that are unable to provide informed consent due to sustaining a head injury or incoherence from narcotics given to them post-injury", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 251 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patient is over the age of 18 years old\n* Underwent surgical treatment for the injuries of interest (stated elsewhere) by an Orthopedic Traumatology Attending Physician at the University of Kansas Hospital\n\nExclusion Criteria:\n\n* Patients that are unable to provide informed consent due to sustaining a head injury or incoherence from narcotics given to them post-injury\n* Chronic opioid use\n* Under the age of 18 years old\n* Undergoing revision surgery\n* Did not undergo surgical fixation\n* Pregnant/nursing women\n* Vulnerable populations as defined by the University of Kansas Medical Center IRB\n* Did not experience one of the following fractures listed in D.1. above.\n* Patients with CKD and/or cirrhosis will be excluded from the opioid-free pain block (block 2) and will only qualify for the standard of care opioid group (Block 1)", "eligibility_sha256": "b1b03a458cc02a174aabc3e59e7c8387d642bd433a64ba2398617fc46eae308a", "enrollment": 250, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "Opioid-free pain treatment" ], "last_update_posted": "2024-10-26", "lead_sponsor": "University of Kansas Medical Center", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT06078371", "official_title": "Peri-operative Opioid-free Analgesic Protocol for Orthopedic Trauma Patients", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "6ce82d1a68e776b9553e173e8d8f1c9bfe4666c5a3a87e174a74b1d9c79ee3ba", "source_url": "https://clinicaltrials.gov/study/NCT06078371", "start_date": "2023-11-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparison of Regional Anaesthesia Methods for Femoral Neck Fracture Surgery", "completion_date": "2025-04-13", "conditions": [ "Femoral Neck Fractures", "Regional Anesthesia" ], "countries": [ "Turkey (T\u00fcrkiye)" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 403, "evidence_id": "f8a80ade85e29406", "matched_rule": "\\bconsent to participate\\b", "quote": "* Patients who did not consent to participate in the study", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 345 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 117, "evidence_id": "df5a46ef64354176", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA (American Society of Anesthesiologists) score between I and IV", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 49 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "92f4edb13ad59b10", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* \\>60 years and \\<90 years\n* ASA (American Society of Anesthesiologists) score between I and IV\n* Patients who will undergo femoral neck fracture surgery\n\nExclusion Criteria:\n\n* Previous local anesthetic allergy\n* Those with bleeding diathesis disorder\n* Having a mental disorder\n* Those who are allergic to the drugs used\n* Patients who did not consent to participate in the study\n* Presence of infection in the block area\n* Body mass index \\>30\n* Preoperative or intraoperative general anesthesia\n* Patients for whom consent cannot be obtained\n* Pregnant patients", "eligibility_sha256": "e94dd77909eeada27b531baa44329f661b4a13b7d9f747cbfa54e2739f23f95c", "enrollment": 115, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "hypobaric spinal anaesthesia", "lumbar plexus block", "hyperbaric spinal anesthesia" ], "last_update_posted": "2026-08-07", "lead_sponsor": "Bursa Yuksek Ihtisas Training and Research Hospital", "masking": null, "maximum_age": "90 Years", "minimum_age": "60 Years", "nct_id": "NCT06224439", "official_title": "Comparison of the Effectiveness of Lumbar Plexus Block and Unilateral Spinal Anaesthesia in Patients Undergoing Femoral Neck Fracture Surgery", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "1ec521697c2c7966e3a1a1957910867d93808231211ba1c0b3c95223c6200617", "source_url": "https://clinicaltrials.gov/study/NCT06224439", "start_date": "2024-01-25", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Fixation of Fracture Neck of Femur in Children", "completion_date": "2026-03", "conditions": [ "Fracture Neck of Femur" ], "countries": [ "Egypt" ], "curation_reason": "Exclusively pediatric population, outside the demo's explicit adult scope.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "a058667f58a1225c", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 14 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* clinical diagnosis of fracture neck of femur\n* children with age less than 14 years old\n\nExclusion Criteria:\n\n* pathological fracture\n* patients with cerebral palsy\n* Associated ipsilateral femoral shaft fracture\n* comminuted fractures\n* old fracture ( \\> 2 weeks)", "eligibility_sha256": "9044d8bdbcd1460591c57602a749edf8bda8e172f244996b0ab661f8c0e3b8ab", "enrollment": 42, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Cannulated screws vs wagner's technique" ], "last_update_posted": "2024-02-20", "lead_sponsor": "Assiut University", "masking": null, "maximum_age": "14 Years", "minimum_age": "1 Year", "nct_id": "NCT06267885", "official_title": "Fixation of Fracture Neck of Femur in Children by Cannulated Screws VS Wagner's Technique.", "operative_candidate": true, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "excluded_screen_candidate", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ff298639505fa21a959cf032873345c1fc7bfd2eb894a1f0c5dca5b208735d61", "source_url": "https://clinicaltrials.gov/study/NCT06267885", "start_date": "2024-03", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Incidence of Cut-out Using Intramedullary Nails With Double Cephalic Screw vs. Unique in Pertrochanteric Fractures", "completion_date": "2026-04-01", "conditions": [ "Proximal Femoral Fractures" ], "countries": [ "Spain" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "accommodating", "end": 311, "evidence_id": "46e038cf4921a782", "matched_rule": "\\binformed consent\\b", "quote": "* Signing of written informed consent according to current legislation before collecting any information, either by the patient or by the legal representative or by people linked by family ties.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 117 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "accommodating" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients with proximal femur fracture (OTA/AO 31-A1, A2 and A3) requiring surgical treatment.\n* Signing of written informed consent according to current legislation before collecting any information, either by the patient or by the legal representative or by people linked by family ties.\n\nExclusion Criteria:\n\n* Presence of other fractures in the ipsilateral femur that condition the surgical treatment of the pertrochanteric femur fracture.\n* Subcapital fracture of the proximal femur.\n* Subtrochanteric fracture of the proximal femur.\n* Pathological fracture.", "eligibility_sha256": "073d63eb5d55cb8456b5aae64c931ac2c9c0632b20faef27fffe3912ce7edeae", "enrollment": 200, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Gamma 3 Nail (Stryker)", "Chimaera Nail (Orthofix)" ], "last_update_posted": "2024-03-05", "lead_sponsor": "Puerta de Hierro University Hospital", "masking": null, "maximum_age": null, "minimum_age": "70 Years", "nct_id": "NCT06293495", "official_title": "Comparison of the Incidence of Cut-out Between Intramedullary Nails With Double Cephalic Screw vs. Unique in Pertrochanteric Fractures: a Prospective Randomized Clinical Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": false }, "overall_status": "UNKNOWN", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4aea48a7225ed2f3910db41097c87feda45c09606185c30a4583bc0dec846c78", "source_url": "https://clinicaltrials.gov/study/NCT06293495", "start_date": "2024-03-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture", "completion_date": "2026-01-07", "conditions": [ "Hip Fracture", "Analgesia Post Fracture" ], "countries": [ "Ireland" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [ { "effect": "mentioned", "end": 39, "evidence_id": "65871c1a042d5345", "matched_rule": "\\bEnglish[- ]speaking\\b", "quote": "* English-speaking", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "mentioned" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* English-speaking\n* over the age of 18 years\n* hemiarthroplasty for fractured neck of femur\n* able to provide written consent.\n\nExclusion Criteria:\n\n* under 50kg body weight.\n* unable to provide consent due to incapacity\n* pregnant women\n* vulnerable adults under state guardianship\n* Patients with pre-existing chronic pain disorders or with a history of long-term opioid use\n* those with contraindications to a peripheral nerve block such as local site infection, allergy to local anaesthetic or those who are coagulopathic", "eligibility_sha256": "e96650f8d4d3191a54267649d7539cb8a495a003114daff96f876aa3a2b58ec9", "enrollment": 150, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "continuous infusion of levobupivacaine", "Programmed Intermittent Bolus of Levobupivacaine" ], "last_update_posted": "2025-07-01", "lead_sponsor": "University College Cork", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT07046052", "official_title": "A Double Blind Randomised Controlled Trial Comparing Continuous Infusion vs. Programmed Intermittent Bolus Via a Pericapsular Nerve Group (PENG) Catheter for Post Operative Fractured Neck of Femur Analgesia", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "3f41fb7a5cc58a267b40e972ad99e4d498f04b7a1e5d988812536add4ab24219", "source_url": "https://clinicaltrials.gov/study/NCT07046052", "start_date": "2024-03-28", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Femoral Nerve Block, Periarticular Nerve Group (PENG) Block, and Preoperative IV Fentanyl", "completion_date": "2025-03-10", "conditions": [ "Postoperative Pain" ], "countries": [ "Egypt" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "823c6a797521d0fb", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 69 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* The included patient should be between 55 to 69 years\n\nExclusion Criteria:\n\n* known allergies to local anesthetics", "eligibility_sha256": "ef66ad0ecdeea68a471888d7c8d284b31867f3deda7db79cb62baa55ca1552e8", "enrollment": 210, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Femoral nerve block with0.25% bupivacaine guided by ultrasound.", "PENG block with0.25% bupivacaine guided by ultrasound.", "Preoperative IV fentanyl 100microgram" ], "last_update_posted": "2025-03-13", "lead_sponsor": "Aswan University Hospital", "masking": null, "maximum_age": "69 Years", "minimum_age": "55 Years", "nct_id": "NCT06537323", "official_title": "Comparative Analysis of Educational Interventions and Anesthetic Techniques for Enhanced Spinal Anesthesia Quality in Fractured Neck of Femur: Femoral Nerve Block, Periarticular Nerve Group (PENG) Block, and Preoperative IV Fentanyl", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "65b44f60af7bfd05d3f8a5bfcd583c4c228d9189d599bacb1214d10ab02698c8", "source_url": "https://clinicaltrials.gov/study/NCT06537323", "start_date": "2024-06-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Lateral Decubitus vs Traction in the Supine Position in Proximal Femoral Nailing. Is There a Huge Difference?", "completion_date": "2025-07-30", "conditions": [ "Unstable Intertrochanteric Fracture" ], "countries": [ "Egypt" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Skeletally mature patients\n* Unstable intertrochanteric fracture ( AO/OTA type 31A2 \\& 31A3 )\n\nExclusion Criteria:\n\n* Patients unfit for surgery\n* Revision cases\n* Patients with multiple or pathological, neglected or open fractures.", "eligibility_sha256": "29b450c10a505293ac8e5bed0bf2a9180898c208d20b6e019181c6b17f69a5cc", "enrollment": 77, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "lateral decubitus postion during proximal femoral nailing for unstable intertrochnateric femur fractures", "Proximal femoral nailing for unstable intertrochnateric femur fractures in supine psoition using traction table" ], "last_update_posted": "2026-02-13", "lead_sponsor": "Ain Shams University", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT07410338", "official_title": "Proximal Femoral Nailing in Unstable Intertrochanteric Fractures: Lateral Decubitus Position Versus Supine Position on Traction Table.", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "57e80aa9d7abc452032677bbd105a667fb3e9ef30e2266777b5e3df1d1dffbd5", "source_url": "https://clinicaltrials.gov/study/NCT07410338", "start_date": "2024-06-30", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Efficacy and Safety of Topical Tranexamic Acid (TXA) Administration Cementless Bipolar Hemiarthroplasty for Femoral Neck Fracture - a Randomized Controlled Trial", "completion_date": "2027-06-30", "conditions": [ "Femoral Neck Fracture" ], "countries": [ "Thailand" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 209, "evidence_id": "6c0dd0de8362c136", "matched_rule": "\\binformed consent\\b", "quote": "* Informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 191 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Elderly patients (age \\> 60 years)\n* Femoral neck fractures from low energy mechanism\n* Household ambulator\n* Undergoing cementless bipolar hemiarthroplasty at KCMH\n* Informed consent\n\nExclusion Criteria:\n\n* Allergy to TXA\n* History of VTE\n* History of hip surgery, pathological fracture, hip infection\n* Congenital or acquired coagulopathy\n* Hb \\< 10 g/dL or Platelet \\< 140,000", "eligibility_sha256": "d470846a37fa451c841845206a6c45f92468ec6df91a5e56b62b3ce35126f439", "enrollment": 75, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Retrograde Intraarticular Injection via Drain Tube", "Topical Soaking of Tranexamic Acid", "Placebo Comparator: Standard procedure (placebo)" ], "last_update_posted": "2026-08-05", "lead_sponsor": "King Chulalongkorn Memorial Hospital", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT06289478", "official_title": "Efficacy and Safety of Retrograde Intraarticular Injection Via Drain Tube, Topical Soaking of Tranexamic Acid (TXA), or Placebo in Elderly Patients With Femoral Neck Fractures Undergoing Bipolar Hemiarthroplasty", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5d313b4f7ee5af8e850c2ccf1fca104bffe18c654e739aff008936de2a8af9cf", "source_url": "https://clinicaltrials.gov/study/NCT06289478", "start_date": "2024-07-03", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)", "completion_date": "2028-06-15", "conditions": [ "Hip Fractures", "Femoral Neck Fractures", "Intertrochanteric Fractures", "Subtrochanteric Fractures" ], "countries": [ "United States" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion:\n\nAge 50 and older Planned surgery to treat a hip fracture\n\nExclusion:\n\nContraindication to spinal anesthesia: current anticoagulant therapy or coagulopathy Contraindication to spinal anesthesia: critical aortic stenosis Contraindication to spinal anesthesia: skin infection over the lumbar spine", "eligibility_sha256": "d135c8dc9c71949c18fc77e6d344e91ee23d1538e64cdeabbdac1b675f197d30", "enrollment": 1881, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "BEHAVIORAL" ], "interventions": [ "My Anesthesia Choice-HF Model" ], "last_update_posted": "2026-03-12", "lead_sponsor": "University of Pennsylvania", "masking": null, "maximum_age": null, "minimum_age": "50 Years", "nct_id": "NCT06438640", "official_title": "Implementation and Evaluation of a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4d11c59bbb2ed68686434be6b18c86a306678609c0fa4ce7e464aec31be845d0", "source_url": "https://clinicaltrials.gov/study/NCT06438640", "start_date": "2024-08-15", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Is Two-on-one Instruction in Virtual Reality Simulation-based Training of Operating Fractures of the Hip for Medical Students as Effective as One-on-one Instruction", "completion_date": "2027-02-15", "conditions": [ "Learning Curves and Outcomes of Simulation-based Training" ], "countries": [ "Denmark" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* PGY 1 and 2 doctors working in an orthopeadic department\n\nExclusion Criteria:\n\n* More than 10 osteosynthesis of proximal femoral fractures performed as the primary surgeon.\n* Failure to achieve mastery within the 4-month follow-up window.s", "eligibility_sha256": "02712491142cca06c720ead78b62c656cac5c668274a844a48e5155030d83be2", "enrollment": 62, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "BEHAVIORAL" ], "interventions": [ "Dyad instruction" ], "last_update_posted": "2026-02-11", "lead_sponsor": "Copenhagen Academy for Medical Education and Simulation", "masking": null, "maximum_age": null, "minimum_age": null, "nct_id": "NCT06612619", "official_title": "Dyad Versus Single Instruction for Simulation-based Training in Proximal Femoral Fracture Osteosynthesis: a Non-inferiority Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ff74157f6b4ac02b6ba3d9b32bfcede17c353b0fae887bd021d7bc77c6d3324c", "source_url": "https://clinicaltrials.gov/study/NCT06612619", "start_date": "2024-10-09", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)", "completion_date": "2026-07-01", "conditions": [ "Femoral Neck Fractures", "Femur Head Necrosis", "Hip Fractures" ], "countries": [ "China" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 71, "evidence_id": "8502055a942aaa20", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* American Society of Anesthesiologists(ASA) I\\~II", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 }, { "effect": "restrictive", "end": 217, "evidence_id": "73e720ee977f1228", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* Presence of severe systemic diseases or ASA grade III or higher", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 152 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "1fb7f23509489484", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 60 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* American Society of Anesthesiologists(ASA) I\\~II\n* Normal coagulation\n* Clinical diagnosis of hip fracture\n\nExclusion Criteria:\n\n* Presence of severe systemic diseases or ASA grade III or higher\n* Allergy to amide local anesthetics", "eligibility_sha256": "119357558c42584dc02d20fabae4370f1f67f7b0994d3e665b4e1b572ce83769", "enrollment": 60, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DRUG" ], "interventions": [ "Liposomal bupivacaine plus bupivacaine", "Ropivacaine" ], "last_update_posted": "2026-03-13", "lead_sponsor": "Huazhong University of Science and Technology", "masking": null, "maximum_age": "60 Years", "minimum_age": "18 Years", "nct_id": "NCT06565910", "official_title": "Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for PENG Block on Post Operative Pain Management in Patients Undergoing Hip Arthroplasty: a Prospective, Randomized, Single Blind, Active Controlled Study", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "46d1cee378c67d7e3b51f7976f829a80aa13f8d14d82a51985c5e83c3c68191c", "source_url": "https://clinicaltrials.gov/study/NCT06565910", "start_date": "2024-12-04", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Motion Graphic Training for Scrub Nurses in Hip Surgery", "completion_date": "2025-07-22", "conditions": [ "Proximal Femoral Fracture", "Dinamic Hip Surgery" ], "countries": [ "Iran" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 242, "evidence_id": "ee8680339a364ae2", "matched_rule": "\\binformed consent\\b", "quote": "* Willingness to participate and provide informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 185 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\nUndergraduate operating room technology student in the 6th or 8th semester\n\n* Completion of the theoretical course in orthopedic operating room technology and care\n* Willingness to participate and provide informed consent\n\nExclusion Criteria:\n\nWithdrawal or unwillingness to continue participation at any stage\n\n* Previous clinical experience in orthopedics that could affect the results\n* Absenteeism or insufficient presence during the internship", "eligibility_sha256": "d536ecd29a4c0bbe05bb3a5932640d9f4c2cee58478a3ec8316d817408588120", "enrollment": 30, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "OTHER" ], "interventions": [ "Motion Graphic Video Training", "Routine Clinical Training" ], "last_update_posted": "2026-07-14", "lead_sponsor": "Arak University of Medical Sciences", "masking": null, "maximum_age": null, "minimum_age": null, "nct_id": "NCT07701564", "official_title": "Motion Graphic Video-Based Training and Its Effect on Scrub Nurse Performance During Dynamic Hip Screw Surgery in Iran: A Pilot Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "c2d463c5fc0edaa5439a8f7f8ee3ecce1fdd25136c8b52c1c649c2e56c83c038", "source_url": "https://clinicaltrials.gov/study/NCT07701564", "start_date": "2024-12-21", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Delayed Supine Position Post-Spinal Compared With Immediate Supine Position in Geriatric Patients", "completion_date": "2026-01-01", "conditions": [ "we Study the Effect of Keeping the Patient Supine 2 Minutes After Spinal Anesthesia in Geriatric Groups" ], "countries": [ "Oman" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "restrictive", "end": 390, "evidence_id": "f9e32663be48f2dc", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA 4.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 382 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria: Geriatric patients (aged 65 years and above) scheduled for surgical fixation of fracture neck of femur under spinal anesthesia were eligible for inclusion\n\n\\-\n\nExclusion Criteria:\n\n* Contraindications to spinal anesthesia (e.g., coagulopathy, local infection, etc.).\n* Haemodynamic instability or baseline systolic BP \\< 90 mmHg.\n* Allergy to study medications.\n* ASA 4.\n* Morbidly obese patients (BMI\\>40).", "eligibility_sha256": "823e3a3e264d27345720f0f4ce50fe025b5954a72579a6ff0e67eb8c9279548b", "enrollment": 90, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "2 minutes setting post spinal anesthesia", "immediate supine position" ], "last_update_posted": "2026-04-09", "lead_sponsor": "Sohar Hospital", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT07520695", "official_title": "Impact of Two Minutes Delayed Supine Position Post-Spinal Compared With Immediate Supine Position in Geriatric Patients Undergoing Repair of Fracture Neck of Femur: A Randomized Controlled Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "7dfa3d6387c50649885ea1bbbc78a76358ed4c3d264130fc9d532eb29c089423", "source_url": "https://clinicaltrials.gov/study/NCT07520695", "start_date": "2025-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparative Effects of Closed Kinetic Chain Exercises and Mobilization Exercises in Elderly Females With NFF", "completion_date": "2026-02-20", "conditions": [ "Neck of Femur Fracture" ], "countries": [ "Pakistan" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "silent" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [ { "effect": "restrictive", "end": 371, "evidence_id": "55a67a51a5a28d98", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Ability to walk normally or with crutches", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 328 }, { "effect": "restrictive", "end": 424, "evidence_id": "e195fca7a7e7959d", "matched_rule": "\\bwalk(?:ing|ed|s)?\\b", "quote": "* Patients walk without any assistance before injury", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 372 }, { "effect": "restrictive", "end": 672, "evidence_id": "aa15ab3582c92e36", "matched_rule": "\\bbedridden\\b", "quote": "* Bedridden patient before fracture", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 637 } ], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "restrictive" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Diagnosed by Orthopedic Surgeon with neck of femur fracture by x ray findings\n* Patients undergone surgical treatment for neck of femur fracture within one year.\n* Patients administer in groups after 12 weeks of post-operative period\n* X-ray reexamination with no fracture or dislocation before treatment\n* Ability to walk normally or with crutches\n* Patients walk without any assistance before injury\n* Un-displaced neck of femur fracture according to Garden Classification\n* Operated on using internal fixation\n* Only females were included\n* Aged 65 years or older\n\nExclusion Criteria:\n\n* Bilateral hip fracture\n* Bedridden patient before fracture\n* Patient who have undergone any previous surgery of lower limb\n* Neurological Condition", "eligibility_sha256": "0ced49e7e6dacfa52d33e87c92e7afb7c4ad8d61a5825c8d2cf23fc6119a2c69", "enrollment": 44, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "COMBINATION_PRODUCT" ], "interventions": [ "Mobilizations Exercises", "Closed Kinetic Chain Exercises" ], "last_update_posted": "2025-03-30", "lead_sponsor": "Superior University", "masking": null, "maximum_age": null, "minimum_age": "65 Years", "nct_id": "NCT06901843", "official_title": "Comparative Effects of Closed Kinetic Chain Exercises and Mobilization Exercises in Elderly Females With Neck of Femur Fracture", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "ACTIVE_NOT_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "FEMALE", "source_sha256": "c6f0770325ff2730169008e9d10ba03216efc3469c715607b6b5c9ccfde45b00", "source_url": "https://clinicaltrials.gov/study/NCT06901843", "start_date": "2025-03-20", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Ultrasound-Guided PENG Block vs Femoral Nerve Block for Analgesia Before Spinal Anesthesia in Hip Fracture Surgery", "completion_date": "2026-05-30", "conditions": [ "Proximal Femur Fracture", "Hip Fracture", "Pain Management", "Spinal Anesthesia" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 701, "evidence_id": "c6ce506858feac20", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Cognitive impairment or inability to comprehend Visual Analog Scale (VAS)", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 626 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "mentioned", "end": 298, "evidence_id": "e018d520320c2d8f", "matched_rule": "\\binformed consent\\b", "quote": "* Provided written informed consent", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 263 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "mentioned" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 200, "evidence_id": "47358d0b80705ed7", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* Classified as American Society of Anesthesiologists (ASA) physical status I, II, or III", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 111 }, { "effect": "restrictive", "end": 519, "evidence_id": "543f13d47c1e7e50", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* Severe cardiopulmonary disease \\[American Society of Anesthesiologists (ASA) \u2265 IV\\]", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 434 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Age \u2265 18 years\n* Scheduled for proximal femur fracture fixation under spinal anesthesia\n* Classified as American Society of Anesthesiologists (ASA) physical status I, II, or III\n* Ability to understand and use the Visual Analog Scale (VAS)\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Coagulopathy\n* Local infection at the injection site\n* Known allergy to local anesthetics or magnesium sulfate\n* Severe cardiopulmonary disease \\[American Society of Anesthesiologists (ASA) \u2265 IV\\]\n* Preexisting diabetic or other neuropathies\n* Chronic opioid use\n* Contraindication to spinal anesthesia\n* Cognitive impairment or inability to comprehend Visual Analog Scale (VAS)", "eligibility_sha256": "7d8963546cba659d6e753f7d43f1e59641abf418008c350b182f52d51d0a861b", "enrollment": 60, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Pericapsular Nerve Group (PENG) Block", "Femoral Nerve Block (FNB)" ], "last_update_posted": "2025-05-25", "lead_sponsor": "Ain Shams University", "masking": null, "maximum_age": null, "minimum_age": "18 Years", "nct_id": "NCT06989047", "official_title": "Comparative Study of Preoperative Ultrasound-Guided Pericapsular Nerve Group Block and Femoral Nerve Block for Analgesia Before Spinal Anesthesia in Proximal Femur Fracture Fixation", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "NOT_YET_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "4762438e1ddd56bd3b772f0a8bc8eafb4a6a5466d9d46f9b66fd452a3121a7a2", "source_url": "https://clinicaltrials.gov/study/NCT06989047", "start_date": "2025-05-30", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures", "completion_date": "2026-03-31", "conditions": [ "Fractures, Hip", "Femoral Neck Fractures", "Intertrochanteric Fractures", "Subtrochanteric Fractures", "Aged", "Frail Older Adults", "Elderly" ], "countries": [ "Croatia" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 233, "evidence_id": "8ac9fedf635687e8", "matched_rule": "\\bdementia\\b", "quote": "* dementia and acute psychosis patients", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 194 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* both sexes\n* 60 years old and older\n* diagnosed with a hip fracture resulting from low-energy trauma\n* scheduled surgery.\n\nExclusion Criteria:\n\n* polytraumatized patients\n* dementia and acute psychosis patients\n* patients for whom spinal anesthesia is contraindicated\n* patients with severe renal failure\n* patients for whom intravenous administration of tranexamic acid is contraindicated\n* patients with proven allergy and contraindications to dexamethasone, non-steroidal anti-rheumatic drugs, opioid analgesics, magnesium sulfate.", "eligibility_sha256": "3a4426b78b103bafd8e97efb6d9a4368ddac181918d59f565510d28910068867", "enrollment": 256, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "PENG and LFCN peripheral nerve blocks with spinal anesthesia", "FN and LFCN peripheral nerve blocks with spinal anesthesia", "FIC peripheral nerve block with spinal anesthesia", "Fentanyl (IV) with spinal anesthesia" ], "last_update_posted": "2025-08-19", "lead_sponsor": "University Hospital of Split", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT07130006", "official_title": "Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures: a Factorial Randomized Clinical Trial", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "NOT_YET_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "ec48e72430b1a11378a27f19c6dd61413cd1dcb35c27e9f8d149280bdad08a05", "source_url": "https://clinicaltrials.gov/study/NCT07130006", "start_date": "2025-08-30", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Effects of Individualized Physical Therapy and Group Physical Therapy on Functional Outcomes in Patients With Femoral Neck Fracture in Gaza Strip", "completion_date": "2025-10-21", "conditions": [ "Orthopaedic Disorders", "Neck of Femur Fracture" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 359, "evidence_id": "bf40d510e713fa0e", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Presence of severe cognitive impairment (e.g., advanced dementia).", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 291 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [ { "effect": "restrictive", "end": 564, "evidence_id": "4a42397ec63cd93e", "matched_rule": "\\binformed consent\\b", "quote": "* Not willing to provide informed consent.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 522 } ], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "restrictive" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "5a04205f88581989", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 65 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients Male and female aged 50 years or older.\n* Diagnosed with unilateral femoral neck fracture and underwent surgical treatment.\n\nExclusion Criteria:\n\n* Patients with bilateral fractures or multiple trauma injuries.\n* Patients with pathological related fractures.\n* Presence of severe cognitive impairment (e.g., advanced dementia).\n* Severe neurological disorders (e.g., stroke, Parkinson's disease) that affect mobility.\n* Unstable cardiovascular conditions that limit exercise participation.\n* Not willing to provide informed consent.\n* Unable to participate in Physical Therapy with or without assistance", "eligibility_sha256": "25e4c93a058a611270747ab5c271660d8f62e9d52f4d9c4b0421f241515d1c73", "enrollment": 40, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "BEHAVIORAL", "OTHER" ], "interventions": [ "physical therapy and exercise", "group physical therapy vs individualized physical therapy", "Group Physical therapy" ], "last_update_posted": "2025-09-11", "lead_sponsor": "Al-Azhar University - Gaza", "masking": null, "maximum_age": "65 Years", "minimum_age": "50 Years", "nct_id": "NCT07168070", "official_title": "Effects of Individualized Physical Therapy and Group Physical Therapy on Functional Outcomes in Patients With Femoral Neck Fracture in Gaza Strip", "operative_candidate": false, "operative_screen": { "device_or_procedure": false, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": false }, "overall_status": "NOT_YET_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "5a2e8e14f86d3434b58e1595720a9bb339005191f7280462307af6a51d6593d9", "source_url": "https://clinicaltrials.gov/study/NCT07168070", "start_date": "2025-09-22", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Comparison Of Preoperative Ultrasound Guided Fascia Iliaca Block Versus Femoral Nerve Block for Proximal Femur Fractures Before Positioning for Spinal Anaesthesia", "completion_date": "2026-06-30", "conditions": [ "Proximal Femur Fractures", "Nerve Block Assessment" ], "countries": [ "Pakistan" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 184, "evidence_id": "3ab6a21c4e6422b2", "matched_rule": "\\bdementia\\b", "quote": "* Patients with history of neurological disease (Alzheimer, dementia),", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 114 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 91, "evidence_id": "64575de0d8a16b92", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* ASA I\\&II status patients coming for proximal femur fracture surgery", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 }, { "effect": "restrictive", "end": 471, "evidence_id": "ee877c867991f815", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* Patients with ASA III and IV status and patients with Known allergy to the study drug were excluded from study.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 358 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "restrictive" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "575795291c370786", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 70 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* ASA I\\&II status patients coming for proximal femur fracture surgery\n\nExclusion Criteria:\n\n* Patients with history of neurological disease (Alzheimer, dementia),\n* Patients with known contraindication to regional anaesthesia (e.g., signs of infection at site of block, coagulation abnormality i.e. INR \\>1.55, platelet count \\<80,000)\n* Patients with ASA III and IV status and patients with Known allergy to the study drug were excluded from study.", "eligibility_sha256": "a66d7253cb6f911856cf6a93dc952940a728c51898a4f26af3a4eef64b79ef05", "enrollment": 84, "enrollment_type": "ACTUAL", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Femoral Nerve Block", "Fascia Iliaca Nerve Block" ], "last_update_posted": "2026-07-21", "lead_sponsor": "Sahara Medical College Narowal Pakistan", "masking": null, "maximum_age": "70 Years", "minimum_age": "20 Years", "nct_id": "NCT07716358", "official_title": "Comparison Of Preoperative Ultrasound Guided Fascia Iliaca Block Versus Femoral Nerve Block for Proximal Femur Fractures Before Positioning for Spinal Anaesthesia", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": false, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "COMPLETED", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "d5df01208c6f0bd9ef7ff9974ccb1593156a5a62e32ca7ec5d33877f36924be0", "source_url": "https://clinicaltrials.gov/study/NCT07716358", "start_date": "2026-01-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia", "completion_date": "2027-08-01", "conditions": [ "Hip Arthroplasty", "Hip Fracture Surgeries", "Femoral Neck Fractures", "Postoperative Pain" ], "countries": [ "Egypt" ], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "restrictive", "end": 763, "evidence_id": "b652026f92fc2890", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* Cognitive impairment preventing pain scoring.", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 716 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [ { "effect": "mentioned", "end": 267, "evidence_id": "60a97a448fb46f07", "matched_rule": "\\bASA(?: class| classification| score)?\\b", "quote": "* Patients with ages from 50 to 90 years of either gender, with diagnosis of intracapsular neck of femur fracture scheduled for elective hip hemiarthroplasty \u2022 Patients with an American Society of Anesthesiologists (ASA) physical status I to III.", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 21 } ], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "mentioned" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [ { "effect": "restrictive", "end": null, "evidence_id": "bcd54b667c7b9270", "matched_rule": "structured maximumAge is present", "quote": "Maximum age: 90 Years", "section": "structured", "source_path": "protocolSection.eligibilityModule.maximumAge", "start": null } ], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "restrictive" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Patients with ages from 50 to 90 years of either gender, with diagnosis of intracapsular neck of femur fracture scheduled for elective hip hemiarthroplasty \u2022 Patients with an American Society of Anesthesiologists (ASA) physical status I to III.\n\nExclusion Criteria:\n\n* \u2022 Patient refusal.\n\n * Allergy to local anesthetics and patient with infection at the injection site of block\n * Patient with contraindication to spinal anesthesia.\n * Coagulopathy as INR\u22651.5 or platelets \u226480\\*103 / microliter)\n * Patients with body mass index\\>35 kg / m2\n * Patients with peripheral neuropathy or diabetic neuropathy\n * Patients receiving opioids for chronic analgesic therapy (cancer, addiction).\n * Cognitive impairment preventing pain scoring.\n * Chronic renal failure requiring dose modification.\n * Bilateral hip fracture or previous ipsilateral hip surgery", "eligibility_sha256": "a49538d939b6150ae9aa46728fe487284db1cf63deb1bd1c051263aa76b72f33", "enrollment": 80, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "PROCEDURE" ], "interventions": [ "Sacral erector spinae plane block", "PENG block" ], "last_update_posted": "2026-03-03", "lead_sponsor": "Fayoum University Hospital", "masking": null, "maximum_age": "90 Years", "minimum_age": "50 Years", "nct_id": "NCT07442721", "official_title": "Sacral Erector Spinae Plane Block Versus Pericapsular Nerve Group Block For Analgesia In Hip Hemi Arthroplasty: A Randomized Comparative Study", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": true, "perioperative_title_exclusion": true }, "overall_status": "RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "9d97883c73118ed2ffb26fb11f7296594bbc153f496fecef898aa9b1bce207ab", "source_url": "https://clinicaltrials.gov/study/NCT07442721", "start_date": "2026-02-01", "study_type": "INTERVENTIONAL" }, { "allocation": "RANDOMIZED", "brief_title": "How TENS Affects Pain, Medication Use, and Muscle Function in Older Adults With Hip Fractures", "completion_date": "2027-01-28", "conditions": [ "Hip Fractures", "Femoral Neck Fractures", "Intertrochanteric Femur Fracture" ], "countries": [], "curation_reason": "Retained in the complete query universe but not selected for the default candidate view.", "domains": { "cognition": { "domain_id": "cognition", "evidence": [ { "effect": "mentioned", "end": 196, "evidence_id": "e87ba29542e7e547", "matched_rule": "\\bmini[- ]mental\\b", "quote": "* Mini-Mental State Examination (MMSE) score \u2265 20", "section": "inclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 147 }, { "effect": "restrictive", "end": 505, "evidence_id": "f65303bc3180dfe4", "matched_rule": "\\bcognit(?:ion|ive|ively)?\\b", "quote": "* History of neurological or cognitive impairment that may interfere with understanding of the assessments", "section": "exclusion", "source_path": "protocolSection.eligibilityModule.eligibilityCriteria", "start": 399 } ], "label": "Cognition", "question": "Does the eligibility text mention cognitive impairment, dementia, delirium, capacity, or a cognitive test?", "state": "restrictive" }, "consent_support": { "domain_id": "consent_support", "evidence": [], "label": "Consent pathway", "question": "Does the record state how consent is handled, including proxy or representative pathways?", "state": "silent" }, "health_status": { "domain_id": "health_status", "evidence": [], "label": "Health and frailty", "question": "Does eligibility depend on frailty, ASA class, severe comorbidity, or clinical fitness?", "state": "silent" }, "language": { "domain_id": "language", "evidence": [], "label": "Language", "question": "Does eligibility depend on a named language or ability to speak, read, or write?", "state": "silent" }, "life_expectancy": { "domain_id": "life_expectancy", "evidence": [], "label": "Life expectancy", "question": "Does eligibility depend on expected survival, terminal illness, or palliative status?", "state": "silent" }, "mobility": { "domain_id": "mobility", "evidence": [], "label": "Mobility and function", "question": "Does eligibility depend on walking, gait, weight-bearing, mobility aids, or pre-fracture function?", "state": "silent" }, "residence": { "domain_id": "residence", "evidence": [], "label": "Residence", "question": "Does the eligibility text mention nursing-home, long-term-care, institutional, or residential-care status?", "state": "silent" }, "upper_age_cap": { "domain_id": "upper_age_cap", "evidence": [], "label": "Upper-age cap", "question": "Does the structured eligibility record specify a maximum age?", "state": "silent" } }, "eligibility_criteria": "Inclusion Criteria:\n\n* Older adults (male and female) diagnosed with hip fracture\n* Age \u2265 60 years\n* Admitted to the hospital inpatient unit (HPS)\n* Mini-Mental State Examination (MMSE) score \u2265 20\n\nExclusion Criteria:\n\n* Conditions contraindicating electrical stimulation, such as presence of a pacemaker, significant sensory loss in the lower limbs, or skin lesions at the electrode placement site\n* History of neurological or cognitive impairment that may interfere with understanding of the assessments\n* Previous treatment with neuromuscular electrical stimulation (NMES) in the lower limb within the last 3 months", "eligibility_sha256": "c4107a2c9265d9a72521a50783c39ce1af877887b9aa4cab01d84ea91075f6d5", "enrollment": 32, "enrollment_type": "ESTIMATED", "has_results": false, "healthy_volunteers": null, "intervention_types": [ "DEVICE" ], "interventions": [ "Active Transcutaneous Electrical Nerve Stimulation (TENS)", "Sham Transcutaneous Electrical Nerve Stimulation (Sham TENS)" ], "last_update_posted": "2026-05-08", "lead_sponsor": "University of the Sinos Valley", "masking": null, "maximum_age": null, "minimum_age": "60 Years", "nct_id": "NCT07567339", "official_title": "Effects of Transcutaneous Electrical Nerve Stimulation (TENS) on Pain and Analgesic Use and the Association of Clinical and Psychosocial Factors With Muscle Function in Older Adults With Hip Fracture", "operative_candidate": false, "operative_screen": { "device_or_procedure": true, "femoral_neck_identity": true, "operative_comparison_terms": false, "perioperative_title_exclusion": true }, "overall_status": "NOT_YET_RECRUITING", "primary_candidate": false, "primary_purpose": null, "record_role": "registry_universe_only", "retrieved_at": "2026-08-14T05:55:35Z", "sex": "ALL", "source_sha256": "bf5fefa78a91047e3cc85edad180907c2d9577bdc8a8b7c5ecbc9c09b7ebe2ee", "source_url": "https://clinicaltrials.gov/study/NCT07567339", "start_date": "2026-05-22", "study_type": "INTERVENTIONAL" } ], "trials_sha256": "1ec3869281a9d06891935acda38d3050b2f9d6c912b012b607b0932de7c546ad" }